Detailed information of component protein


Summary

Component ID T6CP005801
Component protein type TssH
T6SS ID (Type) T6SS00548 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (885 a.a.); Nucleotide sequence (2655 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_23030
Coordinate (Strand) 2332818..2335472 (+)
NCBI ID YP_005226603.1
RefSeq NC_016845
Uniprot ID A0A0H3GSF4_KLEPH
KEGG ID kpm:KPHS_23030
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
AAA_2 PF07724.16 2.9e-38 610..775
AAA_lid_9 PF17871.3 1.4e-30 378..468
ClpB_D2-small PF10431.11 3.3e-12 784..855
AAA PF00004.31 1.5e-09 238..350
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-884 MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSVRHRPQLSDHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRSLLDAQSDERPPAQQEAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGQIDPVFGRDMEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALRIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHITDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPQPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLAAIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEISDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVPLSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTETALALADALFGGEKALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREIDFRNTVILMTANLGSDLLMQLLDEQPQASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQRLACHYGITTTLSESLFAALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGTISDE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8846 - -


  Protein sequence: 885 a.a.    

>T6CP005801 NC_016845:2332818-2335472 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssH]
MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSV
RHRPQLSDHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRSLLDAQSDERPPAQQ
EAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGQIDPVFGRDMEIRQMVDILSRRRKNNPILV
GEPGVGKTALVEGLALRIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIG
AGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHI
TDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPQPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLA
AIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEISDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVP
LSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTETALALADALFGGEK
ALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREI
DFRNTVILMTANLGSDLLMQLLDEQPQASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQR
LACHYGITTTLSESLFAALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGT
ISDE*

  Nucleotide sequence: 2655 bp    

>T6CP005801 NC_016845:2332818-2335472 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssH]
ATGGAAAATCCAGCCAGCCTGTTACGCCGTCTTAATCCCTGCTGTGCCCGCGCAATGGAGGGGGCGGCCTCCCTGTGCCA
GACCCGGGCGCATGCCGAGATCCTGCCCGAGCACTGGCTGCTCAAGCTGCTGGAACAGGGGGAAGGCGATCTGACGGTGC
TGGCGCGGCGCTATGAATGGGATATGGATGCGCTGTGGCAGGATCTGCTGAGCTGGCTGGATAAACAGCCGCGCTCGGTA
CGTCATCGTCCCCAGCTCTCTGACCATACCCTGAGGCTGATGCAGGAGGCCTGGCTGATTGCCTCTCTCAGCGGCGAAGC
GCAGATCCGCAGTGTTCACCTGCTGATGGCGCTGGTTGAAAAACAGAATCTGATCCAGTGCGATGGCCTGTGGCCGCTGT
TAACGCTGGGCCAGCGTCAGCTGGAACGCCTGCGCTCCTTGCTGGATGCCCAGTCCGACGAACGTCCGCCAGCGCAGCAG
GAAGCGGCGCTGGCGCAGCCCCATGGCGGGGACGTGGAATTTGTGGGGCGTCCTGCGGGCAGCGAACTGAATGCGGATGG
GCTCAACCCGGCGCTGCAGAACGCGCTGGACAAATTCACTCTCGACGTCACCGCCAAAGCCAGAGACGGCCAGATTGACC
CGGTGTTCGGACGCGACATGGAAATCCGCCAGATGGTGGATATTCTCTCCCGTCGGCGAAAAAACAACCCGATCCTCGTC
GGTGAGCCGGGCGTGGGCAAGACCGCTCTGGTGGAAGGCCTGGCGCTGCGCATTGCCGAAGGCAACGTCCCCGACGCGCT
GAAGCCAGTGTCGGTGCGCACCCTTGACCTCGGTCTGCTGCAGGCCGGCGCCGGGGTCAAAGGCGAGTTCGAGCAGCGGC
TGAAAAATATCATTGAGGCGGTACAGCAGTCGCCTTCGCCGGTGCTGCTGTTTATCGACGAGGCGCACACGATCATCGGC
GCGGGTAATCAGGCGGGCGGCGCGGATGCCGCCAACCTGCTGAAGCCGGCGCTGGCCCGGGGCGAACTGCGGACCATCGC
CGCCACCACCTGGAGTGAATACAAGCAGTACTTCGAGCGCGACGCCGCGCTGGAGCGCCGCTTTCAGATGGTCAAGGTGG
ATGAGCCGGACGACGACACCGCCTGCCTGATGCTGCGCGGCCTGAAGTCCCGCTATGCCGACCACCACGGCGTGCATATC
ACCGATGATGCGGTGCGCGCCGCCGTGACGCTGTCACGACGCTATCTCACCGGTCGCCAGCTGCCGGACAAGGCAGTGGA
TTTACTCGACACCGCTTCCGCCCGCCTGCGTATGAGTTTGGATACCGTGCCTCAGCCGCTGACCCGCATGAAGGCGCAGC
TCACCGCGCTGGCGATGGAGAAGCAGGCGCTGCTGGAAGATATTGCGCTGGGCAACAGCGCCCGCGGCGATCGGCTGGCG
GCCATTGAGCAGGAGGAGATCCGCCTTATTCTGGCGCTGGATACCCTTGAAACTCAGTATGGTCAGGAGCTGCAGCTGAC
GGAAGCGCTGCTCGCCTGCCGCCGCGATATCTCCCGCCAGGCGGAAATTAGCGATCTACAAACCGCGCTTATCGCCGTCC
AGCAGGGCAATCCGCTGCTCGGGCTGGACGTCGACGTCCGCACCGTGGCGACGGTGATTGCCGACTGGACCGGCGTGCCG
CTCTCCTCGCTAATGAAAGATGAGCAGACGGAGCTTCTGAGTCTGGAAGAGAGTCTCGGCAAACGGGTGGTTGGCCAGGA
GGCGGCCCTGAGCGCTATTGCCCGGCGCCTGCGCGCCGCGAAAACCGGCCTGACGCCGGAGAACGGTCCGCAAGGGGTGT
TCCTGCTGGTCGGGCCGAGCGGCACCGGCAAAACGGAAACGGCGCTCGCCCTGGCCGATGCGCTGTTCGGCGGCGAGAAA
GCGCTGATCACCATCAATCTCTCCGAGTACCAGGAGCCGCACACCGTCAGCCAGCTGAAGGGTTCTCCGCCGGGCTACGT
CGGCTACGGCCAGGGCGGGATCCTGACCGAGGCGGTGCGCAAACGCCCCTACAGCGTGGTGCTGCTCGATGAGGTGGAAA
AGGCCCATCGCGATGTGATGAACCTGTTCTACCAGGTCTTCGACCGGGGGGTAATGCGCGACGGCGAGGGGCGTGAAATC
GACTTTCGCAACACCGTGATCCTGATGACCGCCAACCTCGGTAGCGACCTCCTGATGCAGCTGCTGGATGAACAGCCGCA
GGCCAGCGAATCAGACCTGCACGAGCTGCTGCGCCCGGTGCTGCGCGGCCACTTCCAGCCGGCGCTGCTGGCCCGCTTCC
AGACGGTGATTTACCGTCCGCTGCCGGCGGGAGCGCTGCGCGCCATTGTCGGCATGAAGCTCGGGCAGGTAAGTCAGCGT
CTGGCTTGCCATTACGGAATCACCACCACCCTCAGCGAGAGCCTGTTCGCCGCGCTAACCGAGGCCTGCCTGCTGCCGGA
TACCGGCGCCCGCAACGTCGACAGTCTGCTGAATCAGCAGATCCTGCCGGCGCTGAGTCAGCAGCTATTGAGCCATATGG
CGGCGGGGCAGAAACCGCGCCAGGTGACGCTGGGGTATCACGAAGAGGAAGGCGTCGTGATGGCGTTTGACGAGGGGACA
ATATCCGATGAGTAG