Detailed information of component protein


Summary

Component ID T6CP005800
Component protein type TssK
T6SS ID (Type) T6SS00548 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (448 a.a.); Nucleotide sequence (1344 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_22990
Coordinate (Strand) 2328325..2329668 (+)
NCBI ID YP_005226599.1
RefSeq NC_016845
Uniprot ID A0A0H3GRZ0_KLEPH
KEGG ID kpm:KPHS_22990
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_VasE PF05936.14 2.4e-134 19..444
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-447 MMKTERPLWGRGIMVSPQHFQQQAAYAAWTAEVIARMGLNHPWGVVEATFEPEMLKLGRLQAHRLQVRFQDGTMIDTDNADALPSALSLDGAPGEAVIVLALPLMQANGGNCLKPEEVAERPVRFRQRWRDVRNQFGDDTRQIAVIQPELTLRFAHQDNSDYLTCPLVRLQRDSQGAWLIDETFLSPLLQIQGSRWLATQLEQLLVQLRARLTRLMAMRRESNERMADFAVADVSLFWLLNALNSAEPVLGYFLRYRQSPPERLYPELARLAGSLLTFSLTHQANAVPIYQHDQLNAVFPPLFDLLSDLLEASLPSRVVAIALEHDVRLHFWQARLHDARLREGADYYLSVRSSVPVAQLQEQFPRQCKVGSPDHVKAIVNSSRTGVPLTPLRHVPAAIPLRLENQYFSLDVSHPLATEMLQSGTCMFYVPGMLGEPELELFAVLRT


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9605 - -


  Protein sequence: 448 a.a.    

>T6CP005800 NC_016845:2328325-2329668 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssK]
MMKTERPLWGRGIMVSPQHFQQQAAYAAWTAEVIARMGLNHPWGVVEATFEPEMLKLGRLQAHRLQVRFQDGTMIDTDNA
DALPSALSLDGAPGEAVIVLALPLMQANGGNCLKPEEVAERPVRFRQRWRDVRNQFGDDTRQIAVIQPELTLRFAHQDNS
DYLTCPLVRLQRDSQGAWLIDETFLSPLLQIQGSRWLATQLEQLLVQLRARLTRLMAMRRESNERMADFAVADVSLFWLL
NALNSAEPVLGYFLRYRQSPPERLYPELARLAGSLLTFSLTHQANAVPIYQHDQLNAVFPPLFDLLSDLLEASLPSRVVA
IALEHDVRLHFWQARLHDARLREGADYYLSVRSSVPVAQLQEQFPRQCKVGSPDHVKAIVNSSRTGVPLTPLRHVPAAIP
LRLENQYFSLDVSHPLATEMLQSGTCMFYVPGMLGEPELELFAVLRT*

  Nucleotide sequence: 1344 bp    

>T6CP005800 NC_016845:2328325-2329668 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssK]
ATGATGAAAACGGAACGTCCGTTGTGGGGCCGGGGCATTATGGTGTCGCCTCAGCATTTTCAACAGCAGGCTGCGTATGC
AGCCTGGACTGCGGAAGTGATTGCCCGGATGGGTCTTAACCACCCCTGGGGAGTGGTTGAGGCGACCTTCGAACCAGAGA
TGCTCAAACTGGGCCGCCTGCAGGCTCACAGGCTGCAGGTCCGGTTCCAGGATGGCACGATGATTGATACGGACAATGCC
GATGCGCTGCCGTCCGCGCTGTCGCTGGACGGCGCGCCCGGCGAGGCGGTGATCGTGCTGGCGCTGCCCCTGATGCAGGC
GAATGGCGGCAACTGTCTGAAGCCGGAGGAGGTTGCCGAAAGGCCGGTGCGCTTCCGGCAGCGCTGGCGCGATGTCCGTA
ACCAGTTTGGGGATGATACCCGGCAGATTGCCGTCATACAGCCGGAGCTGACCCTCCGCTTCGCCCACCAGGACAACAGC
GATTACCTGACCTGTCCGCTTGTTCGCCTGCAGCGGGACTCGCAGGGGGCCTGGCTTATCGACGAGACGTTTCTCTCGCC
GCTGCTGCAGATCCAGGGCAGCCGCTGGCTGGCGACGCAGCTTGAACAGCTGCTCGTCCAGCTCCGGGCTCGTCTGACGC
GCCTGATGGCCATGCGTCGCGAAAGCAATGAACGGATGGCTGATTTTGCCGTAGCCGATGTCTCTCTGTTCTGGTTGCTG
AATGCGCTGAACAGCGCCGAACCGGTGCTGGGGTACTTTCTGCGTTACCGGCAAAGCCCGCCGGAACGCCTCTACCCGGA
GCTGGCGCGCCTGGCTGGTAGCCTGCTGACCTTTTCGCTCACCCATCAGGCGAATGCCGTCCCGATCTATCAGCATGACC
AGCTGAACGCGGTTTTTCCGCCGCTGTTTGATTTACTGAGCGACCTGCTGGAGGCGAGCCTGCCATCGCGGGTGGTGGCG
ATTGCCCTGGAGCATGATGTCCGGCTGCACTTCTGGCAGGCGCGTCTGCACGATGCCCGGCTGCGGGAAGGGGCTGATTA
CTACCTGTCGGTTCGTTCGTCGGTACCGGTCGCCCAACTGCAGGAGCAGTTTCCGCGCCAGTGCAAAGTGGGCAGTCCGG
ATCATGTCAAAGCCATCGTCAACTCCTCGCGGACAGGGGTGCCCCTCACGCCATTGCGTCATGTGCCGGCGGCGATCCCG
CTGCGTCTGGAAAATCAGTATTTCAGCCTCGATGTGTCCCACCCTCTGGCAACGGAAATGCTGCAGAGCGGCACCTGTAT
GTTTTACGTCCCGGGGATGCTCGGTGAGCCTGAACTTGAACTTTTTGCGGTACTACGAACGTGA