Detailed information of component protein


Summary

Component ID T6CP005799
Component protein type TssC
T6SS ID (Type) T6SS00548 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (515 a.a.); Nucleotide sequence (1545 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_22980
Coordinate (Strand) 2326771..2328315 (+)
NCBI ID YP_005226598.1
RefSeq NC_016845
Uniprot ID A0A0H3GSE9_KLEPH
KEGG ID kpm:KPHS_22980
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
VipB PF05943.14 1.7e-118 89..389
VipB_2 PF18945.2 2.1e-39 399..509
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-514 MSVTTENAPVQGQTTLQENRAGEGVYASLFEKINLTPASRLGDINDFLDDAALSEAPAAERLTAAMQVFMERIRQSGQRVEKLDKTLIDHHIAELDFQISRQLDAVMHHQEFQQVESLWRGLKQLVDNTDYRQNVKTEILDVAKDDLRQDFEDAPELIQSGMYWHTYTAEYDTPGGEPIGSVISAYEFDASPQDVALLRNISRVSAAAHMPFIGAVGPAFFLKETMEEVAAIKDIGNYFDRAEYIRWKAFRETDDARYIGLVMPRVLGRLPYGPDTVPVRSFNYVEQVKGPDHEKYLWTSAAFSFASNMVKSFVNNGWCVQIRGPQAGGAVKDLPIHLYDLGTGNQVKIPSEVMIPETREFEFASLGFIPLSYYKNRDYACFFSANSAQKPALYDTADATANSRINARLPYIFLLSRIAHYLKMIQRENIGTTKDRRLLELELNTWVRSLVTEMTDPGDELQASHPLRDASVVVEDIEDNPGFFRVKLYAVPHFQVEGMDVNLSLVSQMPKAKA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9876 - -


  Protein sequence: 515 a.a.    

>T6CP005799 NC_016845:2326771-2328315 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssC]
MSVTTENAPVQGQTTLQENRAGEGVYASLFEKINLTPASRLGDINDFLDDAALSEAPAAERLTAAMQVFMERIRQSGQRV
EKLDKTLIDHHIAELDFQISRQLDAVMHHQEFQQVESLWRGLKQLVDNTDYRQNVKTEILDVAKDDLRQDFEDAPELIQS
GMYWHTYTAEYDTPGGEPIGSVISAYEFDASPQDVALLRNISRVSAAAHMPFIGAVGPAFFLKETMEEVAAIKDIGNYFD
RAEYIRWKAFRETDDARYIGLVMPRVLGRLPYGPDTVPVRSFNYVEQVKGPDHEKYLWTSAAFSFASNMVKSFVNNGWCV
QIRGPQAGGAVKDLPIHLYDLGTGNQVKIPSEVMIPETREFEFASLGFIPLSYYKNRDYACFFSANSAQKPALYDTADAT
ANSRINARLPYIFLLSRIAHYLKMIQRENIGTTKDRRLLELELNTWVRSLVTEMTDPGDELQASHPLRDASVVVEDIEDN
PGFFRVKLYAVPHFQVEGMDVNLSLVSQMPKAKA*

  Nucleotide sequence: 1545 bp    

>T6CP005799 NC_016845:2326771-2328315 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssC]
ATGTCTGTTACCACAGAAAACGCCCCTGTTCAGGGGCAAACCACGCTGCAGGAAAACAGGGCGGGCGAGGGCGTTTACGC
CTCGCTGTTTGAAAAAATTAATCTCACCCCGGCGTCTCGCCTCGGGGATATCAACGACTTTCTGGACGATGCCGCGCTCT
CCGAGGCGCCGGCGGCGGAACGTCTCACCGCGGCGATGCAGGTGTTTATGGAACGCATCCGCCAGTCCGGCCAGCGGGTG
GAAAAGCTCGACAAAACGCTGATCGATCACCATATCGCCGAGCTGGATTTCCAGATAAGCCGTCAGCTGGACGCGGTGAT
GCACCATCAGGAGTTTCAGCAGGTCGAATCCCTGTGGCGCGGCCTCAAACAGCTGGTGGACAACACCGACTATCGGCAGA
ACGTCAAAACGGAGATCCTCGACGTCGCCAAAGACGATCTGCGCCAGGACTTTGAGGACGCGCCGGAGCTTATCCAGAGC
GGCATGTACTGGCACACCTATACCGCGGAGTATGACACTCCCGGCGGCGAGCCGATCGGCTCGGTGATCTCGGCCTATGA
GTTCGACGCCAGCCCGCAGGATGTGGCGCTGCTGCGCAATATCTCCCGCGTCTCTGCGGCCGCCCATATGCCGTTTATCG
GCGCCGTCGGCCCGGCCTTCTTCCTGAAAGAGACCATGGAAGAGGTGGCTGCCATTAAGGATATCGGCAACTACTTCGAT
CGTGCGGAATATATCCGCTGGAAGGCGTTTCGCGAAACTGACGATGCCCGCTACATCGGCCTGGTGATGCCGCGCGTGCT
GGGTCGTCTGCCGTACGGTCCGGACACCGTGCCGGTGCGCAGCTTCAACTATGTCGAGCAGGTGAAGGGCCCGGATCACG
AAAAATATCTCTGGACCAGCGCGGCGTTCTCCTTCGCATCTAATATGGTGAAGAGCTTTGTTAACAACGGCTGGTGCGTG
CAAATTCGCGGTCCGCAGGCGGGCGGCGCGGTGAAAGATTTGCCTATCCATCTGTACGATCTGGGCACCGGCAACCAGGT
GAAGATCCCTTCCGAGGTGATGATCCCGGAAACGCGGGAGTTTGAGTTCGCCAGCCTGGGCTTTATCCCGCTGTCGTACT
ACAAAAATCGCGATTACGCCTGCTTCTTCTCGGCCAACTCCGCGCAGAAACCGGCGCTGTACGATACCGCCGACGCCACC
GCCAACAGCCGTATCAACGCGCGTCTGCCTTACATCTTCCTGCTGTCGCGCATCGCGCACTACCTGAAGATGATCCAGCG
CGAAAATATCGGCACCACCAAGGACCGGCGTCTGCTGGAGCTGGAGCTGAACACCTGGGTGCGGAGCCTGGTGACCGAAA
TGACCGACCCCGGCGACGAGCTGCAGGCCTCCCATCCGCTGCGCGATGCCAGCGTGGTGGTGGAAGATATCGAGGATAAC
CCGGGCTTCTTCCGCGTGAAGCTGTACGCGGTGCCGCACTTCCAGGTCGAGGGGATGGACGTCAATCTGTCGCTGGTTAG
CCAGATGCCAAAGGCGAAGGCGTAG