SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP005064
Component protein type	TssD
T6SS ID (Type)	T6SS00069 (Type i3)
Strain	Burkholderia mallei ATCC 23344
Replicon	chromosome II
Sequence	Protein sequence (176 a.a.); Nucleotide sequence (528 bp)
Reference	[1] Schell MA, Ulrich RL, Ribot WJ, et al. Type VI secretion is a major virulence determinant in Burkholderia mallei. Mol Microbiol. 2007 Jun;64(6):1466-85. PMID: 17555434

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	BMA_RS18195
Coordinate (Strand)	436215..436742 (+)
NCBI ID	WP_004196178.1
RefSeq	NC_006349
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_HCP	PF05638.14	7.4e-38	9..150

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-175	MANALVDYFLQIDGVEGESTDQQYPGLIQIQSWQWAEENSGRWGFGSGGGAGKVEMKDFEFRMVSNKASPKLFLMCATGEHIQNAKLICRKSGKGQQEFLTISFASGLVSSFRTLGNMPISQLGHASGEVDGVLPTDQIRINFVQIEFEYREQRNDGTMGAVIKAGYDLKQNAPI

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9890	-	-

Protein sequence: 176 a.a.

						>T6CP005064 NC_006349:436215-436742 [Burkholderia mallei ATCC 23344] [TssD]
MANALVDYFLQIDGVEGESTDQQYPGLIQIQSWQWAEENSGRWGFGSGGGAGKVEMKDFEFRMVSNKASPKLFLMCATGE
HIQNAKLICRKSGKGQQEFLTISFASGLVSSFRTLGNMPISQLGHASGEVDGVLPTDQIRINFVQIEFEYREQRNDGTMG
AVIKAGYDLKQNAPI*					

Nucleotide sequence: 528 bp

						>T6CP005064 NC_006349:436215-436742 [Burkholderia mallei ATCC 23344] [TssD]
ATGGCAAATGCTTTGGTTGATTACTTCTTGCAGATCGATGGCGTCGAGGGTGAGTCGACCGATCAGCAATATCCCGGTCT
GATCCAGATCCAGAGCTGGCAGTGGGCGGAAGAGAACTCGGGCCGCTGGGGCTTCGGCAGCGGCGGCGGCGCGGGCAAGG
TCGAGATGAAGGACTTCGAGTTCCGCATGGTGTCGAACAAGGCGTCGCCGAAGCTGTTCCTGATGTGCGCGACGGGTGAG
CACATCCAGAATGCGAAGCTGATCTGCCGCAAGTCGGGCAAGGGCCAGCAGGAGTTCCTGACGATCTCGTTCGCGAGCGG
CCTCGTGTCGTCGTTCCGCACGCTCGGCAACATGCCGATCTCGCAGCTCGGTCACGCGAGCGGCGAAGTCGACGGCGTGC
TGCCGACGGATCAGATCCGCATCAACTTCGTCCAGATCGAGTTCGAGTACCGCGAGCAGCGCAACGACGGCACGATGGGC
GCCGTGATCAAGGCGGGCTACGACCTGAAGCAGAACGCGCCGATCTAA					