Detailed information of component protein


Summary

Component ID T6CP003510
Component protein type TssI
T6SS ID (Type) T6SS00345 experimental (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (829 a.a.); Nucleotide sequence (2487 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KP1_RS15775
Coordinate (Strand) 3208236..3210722 (-)
NCBI ID WP_014907360.1
RefSeq NC_012731
Uniprot ID A0A652PZ83_9ENTR, A0A331XVI4_KLEPN, A0A3F3BDZ1_KLEPN
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Phage_GPD PF05954.13 2.1e-66 35..355
DUF2345 PF10106.11 1.9e-52 610..758
T6SS_Vgr PF13296.8 7e-32 492..593
Phage_base_V PF04717.14 5.4e-07 405..472
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-828 MDTSSIITGTTLNRYQLDIPSCTASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPAMLTMGGGALQQLADCKRVHGVVTAFRRISSSEDQSKYQITLEPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFYLKQHYPRREQINQYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALMFDKTLPVNSPSGMSDSGAESIWGLSITHNVVEANVTTRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIDPQTETANFYARLDHERFLAHQTLITAISTAAWLAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKANDIYAWQDASGLYRVKFDPDRDEKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDPVTEKNSTRNVIRTPTNNKLRMEDKRGEEHIKLSTEYGGKTQLNLGHNVNAQRELRGEGAELRTDKWVSIRGGAGVFISADKQPSAGDRMLAMEEAIAQLENALGIAKSLASAAESAQALPSDTGNQQTLNDALKELAQPGIVLNAPQGVSISSPQAVRLSSGSASVGIVSQQNTDISALKRFTVAAGEAVSLLARKAGMKLFAAKGKIEIQAQDDALEATAKKDITVTSVEGRVEITAAEELVVNCAGAYIRLSGGNIELGCPGNILLKSANVQKMGAADYDANKPELPVGFSEFFTAKDEESGEILPFTRYRITTGEGKVFEGRTDAEGKTVAVYTALPDALHIELL


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9860 - -


  Protein sequence: 829 a.a.    

>T6CP003510 NC_012731:c3210722-3208236 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssI]
MDTSSIITGTTLNRYQLDIPSCTASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPAMLTMGGGALQQLADCK
RVHGVVTAFRRISSSEDQSKYQITLEPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFYLKQHYPRREQIN
QYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALMFDKTLPVNSPSGMSDSGAESIWGLSITHNVVEANVT
TRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIDPQTETANFYARLDHERFLAHQTLITAISTAAW
LAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKAND
IYAWQDASGLYRVKFDPDRDEKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDP
VTEKNSTRNVIRTPTNNKLRMEDKRGEEHIKLSTEYGGKTQLNLGHNVNAQRELRGEGAELRTDKWVSIRGGAGVFISAD
KQPSAGDRMLAMEEAIAQLENALGIAKSLASAAESAQALPSDTGNQQTLNDALKELAQPGIVLNAPQGVSISSPQAVRLS
SGSASVGIVSQQNTDISALKRFTVAAGEAVSLLARKAGMKLFAAKGKIEIQAQDDALEATAKKDITVTSVEGRVEITAAE
ELVVNCAGAYIRLSGGNIELGCPGNILLKSANVQKMGAADYDANKPELPVGFSEFFTAKDEESGEILPFTRYRITTGEGK
VFEGRTDAEGKTVAVYTALPDALHIELL*

  Nucleotide sequence: 2487 bp    

>T6CP003510 NC_012731:c3210722-3208236 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssI]
ATGGATACCTCTTCAATAATTACCGGCACCACCCTTAACCGTTACCAGCTGGATATTCCTTCATGTACCGCATCGCTGGA
TGTGGAAGAATTCAGTGGGGCAGAAAAACTGAGTGAACTTTATTATTACACTATTACGTTTACCAGCGCAGAGAAAAATA
TTGATGCCGCACAGCTCCTGAGCAAACCCGCCATGCTGACGATGGGCGGCGGCGCACTGCAGCAGCTGGCGGACTGCAAA
CGCGTCCATGGCGTGGTGACTGCCTTCCGGCGTATCAGCAGTTCAGAAGATCAGTCGAAATATCAGATAACCCTCGAACC
CTTCCTCTCCTTACTGGATAAACAGTTTCGCAGCCACCGTTTTTTCGTGAATAAATCGGTGCCGGAGGTGGTGGAGCAGG
TATTGCAGGAACATCACCTGCATGACTGGGAGTATGAGTTTTATCTCAAGCAACACTATCCACGGCGCGAGCAAATTAAT
CAGTATCAGGAGAGCGACCTGGCATTTATCCAGCGCCTGCTGGCAGAGGTGGGGATATTTTATTTCTTCACCCTGCAGGA
AGAGGCGCAGAGCGAAGTGGTTCACTTCGCCGACGCGCAGCGGGCGCTGATGTTCGATAAGACACTTCCTGTAAACAGCC
CGTCCGGGATGAGCGACAGCGGTGCGGAATCGATATGGGGTCTGAGCATCACCCACAACGTCGTAGAGGCGAACGTTACT
ACCCGGGATTATAACCCCCGCGATGCGCAGAGCGTTCTCCAGTCGGCAACAGCGGATATGACCCGGGGAAATGGTGAAGG
CATCACTTACGGTGAGGTATACCACTATAAGCTTCGCCACCGGGAGCGTGGCGATAAAATCGACCCGCAGACGGAGACCG
CCAACTTCTATGCCCGCCTCGACCATGAGCGTTTTCTGGCTCACCAGACGCTTATTACCGCGATCAGTACTGCAGCCTGG
CTGGCGCCGGCCCAGGTGCTGACCGTTACCGACAGCCTGCCGTCGACCCTGCCTGCGCCCGTACAGGATCCGCTGTTAAT
CACCGGCACCGGTTTTACCGCCAGCCGCCGGGAGGCGCTGCGGGTGTCCCTGCTGGCGGTGCCCTACAGCGAAACATTGT
GCTGGCGTCCGCCGCTGCTGCCGCGCCCGAAGGTGACTGGCACCATGACGGCGCGGGTGACCAGCGCGAAAGCGAATGAT
ATCTACGCCTGGCAGGATGCGTCCGGCCTGTACCGGGTGAAATTTGACCCTGACAGAGATGAGAAAGGGCAGGGGCAGGA
AAGCATGCCGGTGCGTCTCGCCAAACCCTACGGCGGCGACGTGTACGGCTTTCACTTCCCGCTGATCCAGGGCACGGAGG
TGGCGATTGCTTTCCACGAAGGCGACCCTGACCGGCCGTATATTGCGCATGCGCTGCACGACTCGCGGCATGTCGATCCT
GTGACGGAGAAAAACAGCACCCGCAATGTGATTCGTACTCCGACCAACAATAAGCTGCGAATGGAGGATAAGCGCGGCGA
GGAGCATATCAAGCTCAGCACCGAGTACGGCGGCAAGACGCAGTTGAACCTGGGGCATAACGTGAATGCGCAGAGGGAGT
TGCGGGGCGAGGGTGCGGAACTGCGTACGGATAAATGGGTGAGCATCCGGGGCGGTGCGGGAGTGTTTATCAGTGCGGAT
AAACAGCCTTCGGCAGGCGACAGGATGCTGGCAATGGAGGAGGCGATTGCGCAGCTTGAAAATGCCCTGGGTATTGCGAA
AAGCCTGGCGTCGGCAGCGGAATCGGCTCAGGCCCTGCCATCGGATACCGGCAACCAGCAGACGCTGAACGATGCGCTGA
AAGAGCTGGCGCAGCCGGGGATAGTGCTGAATGCGCCGCAGGGCGTGAGCATCAGCAGTCCGCAGGCGGTACGGTTGTCT
TCGGGTAGCGCCAGCGTGGGGATTGTGTCACAGCAGAATACGGACATTAGTGCGCTGAAACGTTTTACGGTGGCGGCGGG
AGAAGCCGTCAGCCTGCTGGCGCGAAAGGCGGGGATGAAGCTGTTTGCGGCGAAGGGAAAGATTGAAATCCAGGCGCAGG
ATGATGCGCTGGAGGCGACGGCGAAAAAGGATATCACCGTGACCAGCGTGGAAGGGCGAGTGGAAATCACGGCGGCGGAG
GAACTGGTGGTGAATTGTGCGGGAGCGTATATCAGGCTAAGTGGTGGCAATATCGAGCTGGGCTGCCCTGGGAATATTCT
GCTGAAATCGGCCAATGTGCAGAAAATGGGCGCAGCTGATTATGATGCAAACAAACCTGAGCTTCCCGTCGGTTTCAGTG
AGTTTTTTACTGCAAAAGATGAAGAGTCCGGGGAGATTTTACCTTTTACCCGGTACAGGATAACAACCGGTGAAGGTAAA
GTATTTGAAGGCAGGACCGATGCGGAAGGTAAAACTGTTGCAGTTTATACTGCCCTGCCTGATGCCCTGCATATAGAATT
ACTTTAA