Detailed information of component protein


Summary

Component ID T6CP003509
Component protein type TssM
T6SS ID (Type) T6SS00345 experimental (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (1137 a.a.); Nucleotide sequence (3411 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KP1_RS15715
Coordinate (Strand) 3195777..3199187 (-)
NCBI ID WP_041937785.1
RefSeq NC_012731
Uniprot ID UPI0005A541EB
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 2e-68 416..732
IcmF_C PF06744.14 1.2e-19 988..1094
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-6 MNIPGN
Transmembrane helix 7-29 GLGRFGLAGLTLAGMAAIWWGIT
Outside 30-43 RYGGMLNINTRGEQ
Transmembrane helix 44-63 VLAFVQVCLALVFVFYLPAM
Inside 64-367 SRRVKESLYRRQSQQDSVLPGEEGRVALTPPHHITVGEIRQTLRYQYGRAWSRKVRILLIIGSVRDVEQLTPKLTQELWQEDQGTLLLWGGDPGAAVDNAWFTALRKLRYRPADGMVWVTSGFDGVLTTMKRTKPRLTPDEMDSVSHSLKLRFEALGWKLPLYVWSLYEGGNEKNGRITQPVGCLLPAGCTPQIVAEQFTALASLLIEQGIQQICGQPQHNFLLALADQLTRKPETVTEPLSVLLNPYRPQPLAGVVFSEASVEAGRSVRHHWGRDNRWETIPDSVLWLPAGLRPRKQGVNWMR
Transmembrane helix 368-390 GMSVAAAALMLLWAASMTVSFIA
Outside 391-1136 NRHLVAIAQEQVQQASAGKQPLAVRLHALSALQKTLSQLEYRSQHGAPWYLRAGLSQNDDLLAALFPRYGERAQPLLRDAAAHHLEEQLTAFVQLPPDSPLREKMTKTAYGQLKQYLMLTRPEKMDAAWFATTLMQDWPQRSGIADAVWQGSGPSLLAFYAASLASHPQWRLPVDDGLVSQVRTRLIRQMGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQAVQPAIEKVVAERRDEMDWVLSDTKQTAAQSTLPEALRARLAERYFADFSGAWLDFLNSLRWQRAATLSDAIDQLTLMADVRQSPLVALMNTLRVQGRTGQTGEAIADSLVKSARQLFNRDNPPVIDQRSGARGPLDATFGPVLALLDNRDGGTPTSRLSLQTFLTRVTQVRLRLQQVTNATDPQAMTRLLAQTVFQGKAVDLTETRDYGSLVAAGLGQEWSGFGQTLFVRPMEQAWQQVLTPAAESLNAQWRSAVVEDWNSAFGGRYPFKNTSSEVSLPLLAKYLDSETGRIARFLQTRLNGVLHKEGSRWMADSINAQGLTFNPAFLEAMNTLSHLSDVAFANGEAGLHFALRPGTADGVMQTELVIDSQKLVYMNQMPVWRRFSWPADTEAPGASLSWVSTRAGTRQYGDFPGAWGWIRLLDKAVVSAYPGTSSSWSLSWKAPDGLLLNYTLRTEAGEGPLALLALRNFTLPETIFSVRASAERVPLTDDIPGEEGY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9919 - -


  Protein sequence: 1137 a.a.    

>T6CP003509 NC_012731:c3199187-3195777 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssM]
MNIPGNGLGRFGLAGLTLAGMAAIWWGITRYGGMLNINTRGEQVLAFVQVCLALVFVFYLPAMSRRVKESLYRRQSQQDS
VLPGEEGRVALTPPHHITVGEIRQTLRYQYGRAWSRKVRILLIIGSVRDVEQLTPKLTQELWQEDQGTLLLWGGDPGAAV
DNAWFTALRKLRYRPADGMVWVTSGFDGVLTTMKRTKPRLTPDEMDSVSHSLKLRFEALGWKLPLYVWSLYEGGNEKNGR
ITQPVGCLLPAGCTPQIVAEQFTALASLLIEQGIQQICGQPQHNFLLALADQLTRKPETVTEPLSVLLNPYRPQPLAGVV
FSEASVEAGRSVRHHWGRDNRWETIPDSVLWLPAGLRPRKQGVNWMRGMSVAAAALMLLWAASMTVSFIANRHLVAIAQE
QVQQASAGKQPLAVRLHALSALQKTLSQLEYRSQHGAPWYLRAGLSQNDDLLAALFPRYGERAQPLLRDAAAHHLEEQLT
AFVQLPPDSPLREKMTKTAYGQLKQYLMLTRPEKMDAAWFATTLMQDWPQRSGIADAVWQGSGPSLLAFYAASLASHPQW
RLPVDDGLVSQVRTRLIRQMGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQAVQP
AIEKVVAERRDEMDWVLSDTKQTAAQSTLPEALRARLAERYFADFSGAWLDFLNSLRWQRAATLSDAIDQLTLMADVRQS
PLVALMNTLRVQGRTGQTGEAIADSLVKSARQLFNRDNPPVIDQRSGARGPLDATFGPVLALLDNRDGGTPTSRLSLQTF
LTRVTQVRLRLQQVTNATDPQAMTRLLAQTVFQGKAVDLTETRDYGSLVAAGLGQEWSGFGQTLFVRPMEQAWQQVLTPA
AESLNAQWRSAVVEDWNSAFGGRYPFKNTSSEVSLPLLAKYLDSETGRIARFLQTRLNGVLHKEGSRWMADSINAQGLTF
NPAFLEAMNTLSHLSDVAFANGEAGLHFALRPGTADGVMQTELVIDSQKLVYMNQMPVWRRFSWPADTEAPGASLSWVST
RAGTRQYGDFPGAWGWIRLLDKAVVSAYPGTSSSWSLSWKAPDGLLLNYTLRTEAGEGPLALLALRNFTLPETIFSVRAS
AERVPLTDDIPGEEGY*

  Nucleotide sequence: 3411 bp    

>T6CP003509 NC_012731:c3199187-3195777 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssM]
ATGAATATACCGGGTAATGGCCTGGGCCGGTTTGGCCTGGCCGGGCTTACGTTGGCCGGGATGGCTGCAATATGGTGGGG
GATCACCCGCTATGGCGGCATGCTGAATATCAATACGCGGGGCGAGCAGGTACTGGCGTTTGTCCAGGTCTGTCTGGCGT
TGGTATTTGTTTTTTACCTTCCTGCAATGTCCCGCCGTGTGAAGGAGAGTTTATATCGCCGGCAGTCGCAGCAGGACAGC
GTCTTACCCGGCGAAGAAGGGCGCGTGGCGCTGACACCTCCCCATCATATTACGGTGGGGGAAATTCGCCAGACTCTACG
CTATCAGTATGGACGCGCCTGGTCCCGCAAAGTCCGTATTCTGCTGATAATTGGCTCAGTCAGAGACGTAGAACAACTGA
CCCCAAAGCTCACGCAGGAACTCTGGCAGGAAGATCAGGGTACATTATTGCTGTGGGGTGGAGACCCTGGGGCAGCGGTA
GATAACGCCTGGTTCACAGCGCTGCGTAAACTGCGTTATCGCCCGGCTGATGGTATGGTGTGGGTAACATCGGGCTTTGA
CGGCGTTTTGACAACGATGAAAAGAACGAAGCCCAGGCTCACGCCAGATGAAATGGACAGTGTGTCTCACTCTCTAAAGC
TACGCTTCGAAGCTCTTGGCTGGAAACTACCCCTATACGTCTGGTCGCTGTATGAGGGGGGCAACGAAAAAAATGGACGT
ATCACTCAGCCTGTGGGCTGCCTGTTACCTGCAGGTTGTACGCCGCAAATAGTTGCCGAACAGTTCACTGCCCTGGCGTC
GTTACTGATAGAGCAGGGCATCCAGCAGATATGCGGGCAACCACAGCACAATTTTTTACTCGCGCTGGCCGATCAGTTGA
CCCGTAAACCGGAAACGGTGACGGAGCCGTTATCGGTATTGCTTAATCCTTACCGCCCGCAGCCGCTGGCCGGGGTGGTA
TTTAGTGAGGCGTCAGTAGAGGCTGGTCGCAGTGTCCGTCATCACTGGGGACGGGATAACCGCTGGGAAACGATACCAGA
CTCAGTGCTGTGGTTGCCAGCCGGTCTACGTCCGCGCAAACAGGGAGTCAACTGGATGCGTGGGATGAGCGTGGCCGCCG
CCGCCCTGATGTTACTCTGGGCCGCCTCAATGACAGTCTCTTTTATCGCCAACCGCCACCTGGTGGCGATCGCACAGGAG
CAGGTGCAGCAGGCCTCGGCGGGAAAACAGCCGCTGGCCGTACGCCTGCATGCGCTCTCCGCGTTACAGAAAACGCTTTC
TCAACTGGAATACCGCTCGCAGCACGGAGCGCCGTGGTACCTCCGCGCAGGCCTCAGTCAGAACGATGACCTGCTGGCGG
CGCTGTTCCCGCGCTACGGAGAGAGGGCGCAGCCGCTGCTGCGCGATGCGGCGGCGCATCATCTGGAAGAGCAGCTCACC
GCTTTCGTGCAGCTGCCGCCGGACAGCCCACTGCGTGAGAAGATGACGAAGACCGCTTACGGACAACTGAAACAATATCT
GATGTTGACCCGCCCGGAAAAAATGGACGCCGCGTGGTTCGCCACTACGCTAATGCAGGACTGGCCGCAGCGCTCAGGCA
TCGCCGACGCCGTCTGGCAGGGCAGCGGCCCTTCGCTGCTGGCATTTTATGCCGCCAGTCTGGCGTCGCATCCGCAGTGG
CGTCTGCCTGTCGATGACGGTCTGGTCAGCCAGGTGCGCACACGGTTAATTCGACAGATGGGCCAGCGCAACAGTGAGTC
CACGCTTTACCAGAAGATGCTCGCGCAGGTGGCGAATCAGTATGCCGATATGCGCCTGGCGGATATGACTGCCGACACCG
ATGCTTCGCGTCTGTTCAGCACTGATGAGGTGGTGCCGGGAATGTTTACCCGTCAGGCCTGGGAGCAGGCCGTGCAGCCG
GCCATTGAGAAAGTGGTCGCGGAACGCCGCGATGAAATGGACTGGGTGCTGAGTGATACGAAGCAGACTGCCGCGCAGTC
GACGTTGCCGGAAGCTCTGCGAGCCAGGCTGGCGGAGCGTTATTTCGCTGATTTTAGCGGCGCCTGGCTGGATTTCCTCA
ACAGTCTGCGCTGGCAGCGCGCGGCAACCCTCTCCGATGCTATCGACCAGCTGACCCTGATGGCCGATGTGCGCCAGTCG
CCGCTGGTGGCGCTGATGAACACCCTGCGCGTGCAGGGGCGAACCGGCCAGACCGGGGAAGCCATCGCCGATTCGCTGGT
CAAATCGGCCAGGCAGCTGTTCAACCGTGACAACCCGCCCGTCATCGATCAACGGTCCGGCGCGCGCGGTCCTCTGGATG
CCACCTTCGGGCCCGTACTGGCGCTGCTGGACAATCGCGACGGCGGGACACCCACCAGCCGTCTTAGCCTGCAGACCTTC
CTGACCCGCGTCACCCAGGTGCGTCTGCGCCTGCAGCAGGTCACCAACGCCACCGATCCGCAGGCGATGACCCGGTTGCT
TGCGCAGACGGTATTCCAGGGCAAGGCCGTGGATTTAACCGAAACGCGCGACTACGGCAGCCTGGTGGCGGCGGGGCTGG
GCCAGGAGTGGAGTGGATTTGGGCAAACGCTGTTTGTTCGCCCAATGGAACAGGCCTGGCAGCAGGTGCTGACCCCGGCG
GCGGAAAGCCTCAACGCCCAGTGGCGCAGCGCGGTGGTGGAGGACTGGAATAGCGCTTTTGGCGGTCGCTACCCCTTTAA
AAATACCAGCAGTGAAGTCTCTCTGCCGCTGCTGGCAAAATACCTCGACAGCGAGACCGGGCGCATCGCCCGCTTTCTGC
AGACCCGGCTGAACGGCGTGCTGCATAAAGAGGGGAGCCGCTGGATGGCGGACAGTATCAATGCTCAGGGGCTGACGTTT
AACCCGGCCTTTCTGGAGGCGATGAATACCCTGAGCCATCTCTCCGACGTCGCGTTCGCCAACGGCGAAGCGGGATTGCA
TTTTGCGCTTCGCCCCGGCACGGCGGACGGCGTGATGCAGACGGAGCTGGTCATCGACAGTCAGAAACTTGTCTATATGA
ACCAGATGCCGGTCTGGCGGCGGTTCAGCTGGCCCGCTGACACCGAAGCGCCGGGCGCCAGTCTGAGCTGGGTCAGTACC
CGGGCGGGCACCCGCCAGTATGGCGATTTCCCGGGCGCCTGGGGGTGGATCCGTCTGCTGGATAAGGCGGTGGTCAGCGC
TTATCCCGGAACGAGCAGCAGCTGGAGCCTGAGCTGGAAAGCGCCGGATGGTCTGTTGCTGAACTACACGCTGCGTACCG
AGGCGGGGGAAGGACCGCTGGCGCTGCTGGCGCTGCGAAACTTTACGCTACCGGAGACGATATTCAGCGTGCGCGCGTCT
GCTGAACGTGTTCCGCTGACCGACGATATACCCGGCGAAGAGGGATACTGA