Detailed information of component protein


Summary

Component ID T6CP003502
Component protein type TssM
T6SS ID (Type) T6SS00344 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (1152 a.a.); Nucleotide sequence (3456 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KP1_RS11295
Coordinate (Strand) 2318471..2321926 (+)
NCBI ID WP_049127998.1
RefSeq NC_012731
Uniprot ID UPI0006589734
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 7.2e-61 426..743
IcmF_C PF06744.14 1.3e-21 1002..1106
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-11 VKLLLAPKTTE
Transmembrane helix 12-34 GRYLSVVFILFLLLAAMTFIVWK
Outside 35-48 HPDMAGLEGDSQQQ
Transmembrane helix 49-71 NYWLIGGCCITGCIFIMLVMLLW
Inside 72-377 TARSAGKKEFEALLDVTRGDDNKRKDESENISVSPAVVMCARIRDHLRTRIGIHWRRKVRLLLVTGDEAAIEQLVPGLRQQHWLEGNRTVLIYGGSLASEPDREKYIALRKLRRGRPLDGIVRVMPSSLTLTPQISESDLHGLEKISELLGYAAPVWLWKLCDSEWPQADRAVQAVGVSFPLRATEDDVARQLAQMLPTLREQGMRQIAEETRHDFLLRLGQQLIDGGIAQWRWQLAPWLTASRQRLALRGLMFSLPEPRTVDPYQEADTSPVGQPHLLTLPATWLGIVDDCRRLRGHHVGMAWER
Transmembrane helix 378-400 GLACGLLAILGLWAAGLLLSFAL
Outside 401-1151 NYSQIASVAGKARDLVAHPSVSDYQLTALHALRNEAGRLVHDGQKGAPWYRRFGLDHHQQLLNAVLPWYGVANHRLIRDPANAALQQALNALVNSAPNSDQRAKLAKPGYDQLKAWLMMARPDKADGAFFAQTMKTVQPTRMGISTGLWQSLAPDLWAFYLSLLPERPEWKIIPDAQRVSQSRQVLLQQLGRRNAESTLYENMLKSVRRNFADVSLEDMTSGTDARRLFTTDEVVPGMFTRQAWEGGIQQAIDKAASSRREEIDWVLSDSRKTVSTDLSPEALKARLTRRYFTDFAGSWLNFLNSLRLNPATNIADVTDQLTLISDVRQSPLIALMNTLAWQGQAGQQREGLSDSLIKSAKDLVGGKDKPVIDQSAAGPQGPLDDTFGPLLQLMGKNTGSNVMSADSTLSLQTYLTRITRVRLRLQQVANASDPQVMMQTLAQTVFQGKSVDLTDTQQYGSLISASLGEEWSGFGNTLFVQPLTQAWETVLLPSAASLNDKWRRSVVANWHTAFDGRFPFAASKSDASLPMLAEFVRKDSGRIERFLTTELNGVLHKEGSQWVPDKVNSHGLVFNPAFLRAIDQLSQLSDILFTDGSQGISFELQARPAPEVVETQLTIDGQKLRYFNQMADWQTFRWPGETYKPGTLLTWTTVNAGTRLFGDYSGTWGFIRWLEQGKRHPLDRSQWMMSFSAPDGRTLQWVLRSQLGSGPLALLALRGLTLPDQIFTVDAAESAQALTTGVGNSDMDEME


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9873 - -


  Protein sequence: 1152 a.a.    

>T6CP003502 NC_012731:2318471-2321926 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssM]
VKLLLAPKTTEGRYLSVVFILFLLLAAMTFIVWKHPDMAGLEGDSQQQNYWLIGGCCITGCIFIMLVMLLWTARSAGKKE
FEALLDVTRGDDNKRKDESENISVSPAVVMCARIRDHLRTRIGIHWRRKVRLLLVTGDEAAIEQLVPGLRQQHWLEGNRT
VLIYGGSLASEPDREKYIALRKLRRGRPLDGIVRVMPSSLTLTPQISESDLHGLEKISELLGYAAPVWLWKLCDSEWPQA
DRAVQAVGVSFPLRATEDDVARQLAQMLPTLREQGMRQIAEETRHDFLLRLGQQLIDGGIAQWRWQLAPWLTASRQRLAL
RGLMFSLPEPRTVDPYQEADTSPVGQPHLLTLPATWLGIVDDCRRLRGHHVGMAWERGLACGLLAILGLWAAGLLLSFAL
NYSQIASVAGKARDLVAHPSVSDYQLTALHALRNEAGRLVHDGQKGAPWYRRFGLDHHQQLLNAVLPWYGVANHRLIRDP
ANAALQQALNALVNSAPNSDQRAKLAKPGYDQLKAWLMMARPDKADGAFFAQTMKTVQPTRMGISTGLWQSLAPDLWAFY
LSLLPERPEWKIIPDAQRVSQSRQVLLQQLGRRNAESTLYENMLKSVRRNFADVSLEDMTSGTDARRLFTTDEVVPGMFT
RQAWEGGIQQAIDKAASSRREEIDWVLSDSRKTVSTDLSPEALKARLTRRYFTDFAGSWLNFLNSLRLNPATNIADVTDQ
LTLISDVRQSPLIALMNTLAWQGQAGQQREGLSDSLIKSAKDLVGGKDKPVIDQSAAGPQGPLDDTFGPLLQLMGKNTGS
NVMSADSTLSLQTYLTRITRVRLRLQQVANASDPQVMMQTLAQTVFQGKSVDLTDTQQYGSLISASLGEEWSGFGNTLFV
QPLTQAWETVLLPSAASLNDKWRRSVVANWHTAFDGRFPFAASKSDASLPMLAEFVRKDSGRIERFLTTELNGVLHKEGS
QWVPDKVNSHGLVFNPAFLRAIDQLSQLSDILFTDGSQGISFELQARPAPEVVETQLTIDGQKLRYFNQMADWQTFRWPG
ETYKPGTLLTWTTVNAGTRLFGDYSGTWGFIRWLEQGKRHPLDRSQWMMSFSAPDGRTLQWVLRSQLGSGPLALLALRGL
TLPDQIFTVDAAESAQALTTGVGNSDMDEME*

  Nucleotide sequence: 3456 bp    

>T6CP003502 NC_012731:2318471-2321926 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssM]
GTGAAGTTACTTTTAGCACCGAAAACTACGGAAGGTCGCTATCTTTCAGTCGTATTCATTCTCTTTTTACTCTTGGCTGC
AATGACATTTATCGTCTGGAAACATCCTGACATGGCCGGACTTGAGGGCGATAGTCAGCAGCAGAATTACTGGCTTATTG
GTGGGTGCTGCATTACCGGATGTATCTTTATCATGTTAGTTATGCTCCTGTGGACAGCTCGCAGTGCCGGTAAAAAGGAG
TTTGAGGCGCTCCTGGATGTCACTCGTGGTGATGACAATAAGAGAAAAGATGAGAGTGAAAACATCTCTGTTTCTCCAGC
AGTGGTGATGTGTGCCAGGATTCGTGACCATCTGCGAACCCGAATTGGAATTCACTGGCGGCGCAAAGTCCGCCTGCTTT
TAGTCACCGGCGACGAGGCGGCAATCGAACAACTGGTGCCTGGCCTGCGTCAGCAGCACTGGCTTGAAGGCAACCGCACC
GTGCTGATTTACGGCGGCAGCCTTGCATCGGAGCCTGACCGAGAAAAATACATCGCGCTGCGCAAGCTGCGCCGTGGCCG
TCCTCTGGACGGAATTGTGCGGGTGATGCCGTCGTCTCTCACCCTGACGCCGCAGATAAGCGAGAGCGACCTGCACGGGC
TGGAAAAAATCAGCGAACTGCTGGGCTATGCCGCCCCGGTCTGGTTGTGGAAACTATGCGATAGTGAGTGGCCGCAGGCT
GACCGCGCGGTGCAGGCGGTAGGGGTTAGCTTCCCGTTGCGCGCTACCGAGGACGATGTCGCCCGTCAGCTTGCGCAGAT
GCTGCCCACGCTGCGGGAGCAGGGGATGCGCCAGATCGCGGAGGAGACCCGCCACGACTTTCTGCTGCGTCTGGGACAGC
AGCTTATCGACGGGGGGATCGCGCAATGGCGCTGGCAGCTGGCGCCGTGGCTGACCGCCTCGCGGCAGCGGCTTGCGCTG
CGAGGCCTGATGTTTAGCCTGCCAGAGCCTCGTACCGTAGATCCGTATCAGGAGGCGGATACCTCGCCTGTGGGCCAGCC
TCATCTCCTGACGCTGCCCGCCACCTGGCTGGGGATCGTCGATGACTGCCGCCGTTTACGCGGGCATCACGTGGGAATGG
CGTGGGAGCGGGGCCTGGCGTGCGGTCTGCTGGCCATCCTCGGCCTGTGGGCGGCGGGACTGCTGCTCTCCTTTGCCCTC
AATTACAGTCAGATTGCTTCGGTAGCGGGAAAAGCCCGCGACCTGGTGGCCCACCCCTCCGTTTCTGACTATCAACTGAC
GGCCCTCCATGCCCTGCGCAATGAGGCCGGCCGTCTCGTGCACGATGGGCAGAAGGGGGCGCCCTGGTATCGGCGCTTTG
GTCTGGACCATCATCAGCAACTATTAAACGCCGTCCTACCCTGGTACGGTGTGGCAAATCATCGCCTGATACGTGACCCG
GCCAATGCCGCGTTGCAGCAGGCGCTCAACGCGCTGGTCAACTCCGCCCCCAATAGCGACCAACGAGCCAAGCTGGCGAA
ACCGGGCTATGACCAGCTGAAAGCCTGGCTGATGATGGCTCGTCCGGATAAAGCCGATGGCGCATTTTTTGCGCAGACCA
TGAAAACGGTCCAGCCGACGCGAATGGGGATCTCGACCGGTCTGTGGCAAAGTCTGGCGCCGGATTTGTGGGCCTTTTAT
CTCTCCCTGCTGCCCGAGCGGCCAGAGTGGAAGATCATCCCGGATGCGCAACGGGTGAGTCAGAGCCGTCAGGTTCTGTT
GCAGCAGCTAGGTCGCCGCAATGCCGAAAGCACCTTATATGAGAACATGCTCAAATCCGTGCGTCGTAATTTTGCCGATG
TATCGCTGGAAGACATGACCAGTGGCACCGATGCGCGCCGGCTGTTTACCACCGATGAAGTGGTCCCGGGGATGTTTACC
CGCCAGGCATGGGAAGGCGGCATTCAGCAGGCCATTGATAAGGCAGCCAGCTCGCGCCGGGAGGAAATCGACTGGGTGCT
GAGCGATTCGCGCAAAACGGTGTCGACAGACCTGTCGCCGGAGGCGCTGAAAGCGCGTCTGACCCGACGCTACTTCACCG
ATTTCGCCGGCAGCTGGCTGAATTTTCTCAACAGTCTGCGACTTAATCCGGCGACCAATATCGCCGATGTTACCGACCAG
CTCACGCTGATTAGCGATGTCCGCCAGTCGCCGCTGATTGCCCTGATGAATACCCTTGCCTGGCAGGGGCAGGCGGGGCA
ACAAAGGGAGGGGCTGTCGGACAGCCTTATTAAATCGGCCAAAGATCTGGTGGGCGGGAAAGACAAGCCGGTCATCGACC
AGTCGGCAGCCGGCCCGCAGGGGCCTCTGGATGACACGTTCGGCCCACTGCTCCAGCTGATGGGGAAAAACACGGGCAGC
AACGTCATGTCGGCCGATAGCACCCTGAGCCTGCAAACCTATCTGACCCGTATCACCCGCGTGCGCCTGCGCCTGCAGCA
GGTTGCGAATGCTTCCGATCCGCAGGTGATGATGCAGACCCTGGCGCAGACCGTCTTCCAGGGGAAAAGCGTCGACCTGA
CCGACACGCAACAGTACGGTAGCCTGATTTCGGCAAGCCTTGGCGAAGAGTGGAGTGGCTTCGGTAATACTCTGTTTGTG
CAGCCGCTGACTCAGGCCTGGGAAACCGTGCTTCTGCCGTCGGCGGCCAGTCTGAATGATAAATGGCGCCGCTCGGTGGT
CGCCAACTGGCACACCGCCTTTGACGGACGCTTTCCGTTTGCCGCCAGCAAAAGCGACGCCTCCCTGCCGATGCTGGCTG
AGTTTGTGCGCAAAGACAGCGGGCGAATCGAACGTTTTCTCACGACGGAGCTGAACGGTGTCCTGCATAAAGAAGGTAGT
CAGTGGGTGCCGGATAAGGTCAACAGTCACGGCCTGGTCTTTAATCCGGCCTTTCTGCGCGCGATCGACCAGCTAAGCCA
GCTGTCCGACATTCTTTTCACCGACGGCAGCCAGGGGATCAGCTTTGAGTTACAGGCCAGGCCTGCCCCGGAGGTTGTCG
AGACACAGCTGACGATAGACGGCCAAAAGCTGCGCTATTTCAATCAGATGGCCGACTGGCAGACTTTCCGCTGGCCGGGG
GAGACGTATAAACCCGGCACTCTGCTGACCTGGACCACCGTCAATGCGGGAACGCGTCTGTTCGGTGACTACAGCGGTAC
CTGGGGCTTTATTCGCTGGCTGGAGCAGGGTAAACGCCATCCGCTGGATCGCAGCCAGTGGATGATGAGCTTCTCCGCTC
CGGATGGCCGCACCCTGCAGTGGGTATTGCGCTCCCAGCTTGGGAGTGGCCCGCTGGCGCTTCTGGCGCTGCGCGGATTG
ACCCTGCCGGATCAGATTTTCACTGTCGATGCGGCTGAGAGCGCACAGGCCCTGACGACGGGGGTAGGGAATAGTGACAT
GGATGAGATGGAATAA