Detailed information of component protein


Summary

Component ID T6CP003501
Component protein type TssI
T6SS ID (Type) T6SS00344 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (900 a.a.); Nucleotide sequence (2700 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KP1_RS11255
Coordinate (Strand) 2308087..2310786 (+)
NCBI ID WP_041168969.1
RefSeq NC_012731
Uniprot ID A0A652Q1B0_9ENTR, A0A332MD09_KLEPN
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Phage_GPD PF05954.13 2.6e-59 34..354
DUF2345 PF10106.11 1.6e-47 613..752
T6SS_Vgr PF13296.8 5.4e-35 493..592
Phage_base_V PF04717.14 3.5e-09 407..474
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-899 MSSVKSLLFSHNHHLLSVKGCEAGLDVLAFEGDEALSQPFRYRIEFTSADHAISKEMMLMKAASLTLQAPVAQGFGINVQQPVRVIQGVVTGFERLSTSRDETHYALTLQPRLALLNRSHQNAIYQDQSVPQIVEKILRERHGLRGQDFLFSLTKTYPRREQVMQYGEDDLRFITRLLGEVGIWFRFTADTRLHIDVAEFCDSQQGYEKGLTLPSVPPSGQQSAGVDAVWEMACRHRVVEQQVSTRDYNYREATADMNAQVDVTRGETTTFGEAYHWGDNYLTAGNVHDRHPAPESGAFYARLRHERYLNGQTRMQATTSCPTLCPGQVLKVTGGEEVAGEFADGVLVTAMHSHARRDADFAVEFAGIPDSPDVGYRPEPGARPVMAGTLPARVTSTRENDTYGHIDKHGRYRVNMLFDRARWETGFESLWVRQSRPYAGDTYGLHLPLLAGTEVAIGFEDGNPDRPYIAGVLHDSAHGDHVTIRNDKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQLNLGHLVDAEKQPRGEGFELRTDSWGAIRAQKGIFISADGQVQAQGQVLDMEPAVSNLAEAREQMMSISGDAQKATANPADLQAQITLLEQQLTDLKKSVLLVSAPEGIALTSGEHLQVSAGHNLIATAGKNADVSVVKNLFIGVGSALSVFVRKLGIRLIANQGPVQMQAQNDLMALLARKEISIVSTEDEIKIIAKKKLTLNGGGSYIRLDANAIESATAGEYRTKAGYYGRQESASEKVKMPVFPVMEPGEHSLRFAFPGADSVSQSMNWLINQPYSISDSAGKILSTGTVDTSGRFPKIVLPESDTLNLIIGRETWSKEELSVSSTEDDSMEDFEDEAPDADLHLSEMGFEDDRTSALTESMISTLLSLTKDS


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9393 - -


  Protein sequence: 900 a.a.    

>T6CP003501 NC_012731:2308087-2310786 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssI]
MSSVKSLLFSHNHHLLSVKGCEAGLDVLAFEGDEALSQPFRYRIEFTSADHAISKEMMLMKAASLTLQAPVAQGFGINVQ
QPVRVIQGVVTGFERLSTSRDETHYALTLQPRLALLNRSHQNAIYQDQSVPQIVEKILRERHGLRGQDFLFSLTKTYPRR
EQVMQYGEDDLRFITRLLGEVGIWFRFTADTRLHIDVAEFCDSQQGYEKGLTLPSVPPSGQQSAGVDAVWEMACRHRVVE
QQVSTRDYNYREATADMNAQVDVTRGETTTFGEAYHWGDNYLTAGNVHDRHPAPESGAFYARLRHERYLNGQTRMQATTS
CPTLCPGQVLKVTGGEEVAGEFADGVLVTAMHSHARRDADFAVEFAGIPDSPDVGYRPEPGARPVMAGTLPARVTSTREN
DTYGHIDKHGRYRVNMLFDRARWETGFESLWVRQSRPYAGDTYGLHLPLLAGTEVAIGFEDGNPDRPYIAGVLHDSAHGD
HVTIRNDKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQLNLGHLVDAEKQPRGEGFELRTDSWGAIRAQKGIFISA
DGQVQAQGQVLDMEPAVSNLAEAREQMMSISGDAQKATANPADLQAQITLLEQQLTDLKKSVLLVSAPEGIALTSGEHLQ
VSAGHNLIATAGKNADVSVVKNLFIGVGSALSVFVRKLGIRLIANQGPVQMQAQNDLMALLARKEISIVSTEDEIKIIAK
KKLTLNGGGSYIRLDANAIESATAGEYRTKAGYYGRQESASEKVKMPVFPVMEPGEHSLRFAFPGADSVSQSMNWLINQP
YSISDSAGKILSTGTVDTSGRFPKIVLPESDTLNLIIGRETWSKEELSVSSTEDDSMEDFEDEAPDADLHLSEMGFEDDR
TSALTESMISTLLSLTKDS*

  Nucleotide sequence: 2700 bp    

>T6CP003501 NC_012731:2308087-2310786 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssI]
ATGAGTAGCGTGAAATCGTTGTTGTTCAGCCATAACCACCACCTGCTTTCGGTGAAGGGATGTGAAGCCGGGCTTGATGT
GCTGGCCTTCGAGGGCGATGAAGCCCTGAGCCAGCCGTTCCGCTACCGTATTGAATTCACCAGCGCAGACCATGCCATCA
GCAAAGAGATGATGCTGATGAAGGCAGCCTCCCTGACGCTGCAGGCGCCGGTGGCTCAGGGCTTCGGCATCAATGTTCAG
CAACCCGTGCGGGTGATCCAGGGCGTGGTGACGGGGTTTGAACGGCTCAGTACCTCCAGGGATGAAACGCACTACGCGCT
GACGCTTCAGCCGCGCCTGGCGCTGCTTAACCGCTCGCACCAGAACGCCATTTACCAGGACCAGTCCGTTCCGCAGATTG
TGGAAAAAATCCTCCGCGAGCGCCACGGCCTGCGCGGTCAGGATTTTCTGTTCTCGCTGACAAAAACGTATCCGCGACGC
GAGCAGGTGATGCAGTACGGCGAGGATGACCTGCGCTTTATCACCCGGCTGCTGGGTGAGGTGGGGATCTGGTTTCGGTT
TACCGCCGACACGCGGCTGCACATCGACGTCGCTGAGTTCTGCGACAGTCAGCAGGGCTATGAGAAGGGGCTGACGTTGC
CTTCGGTCCCGCCGTCAGGGCAGCAGTCGGCCGGGGTGGACGCGGTGTGGGAGATGGCATGTCGCCACCGCGTCGTGGAG
CAGCAGGTCAGTACCCGCGACTACAACTACCGCGAGGCGACGGCGGACATGAACGCGCAGGTGGATGTCACCCGCGGGGA
GACCACTACCTTTGGTGAGGCTTACCACTGGGGAGATAACTACCTGACCGCGGGGAATGTCCATGACCGCCATCCGGCGC
CGGAGTCCGGGGCGTTTTACGCCCGGCTTCGGCATGAGCGTTATCTTAACGGCCAGACCCGGATGCAGGCCACCACCAGC
TGCCCGACGCTCTGCCCGGGACAGGTGCTGAAGGTCACCGGCGGAGAGGAGGTGGCCGGGGAGTTTGCTGATGGCGTGCT
CGTCACGGCGATGCACAGCCACGCCCGGCGCGATGCCGACTTTGCGGTGGAGTTTGCCGGCATACCGGACAGCCCGGACG
TCGGCTACCGGCCTGAGCCCGGCGCGCGTCCGGTGATGGCCGGGACGCTGCCGGCCCGCGTGACCAGCACCCGGGAAAAC
GACACCTACGGGCATATCGACAAACACGGACGCTACCGGGTGAATATGCTGTTTGACCGGGCGCGCTGGGAAACCGGTTT
CGAGAGCCTGTGGGTCCGCCAGTCGCGGCCGTATGCCGGAGACACCTACGGCCTGCACCTGCCGCTGCTGGCCGGGACGG
AGGTGGCGATTGGCTTTGAGGATGGTAACCCTGACCGGCCGTATATCGCGGGCGTGCTGCACGACTCGGCGCACGGCGAC
CACGTCACCATCCGCAATGACAAACGTAACGTCCTGCGCACCCCGGCCAACAACAAAATCCGCCTCGACGATGAGCGCGG
AAAAGAGCATATCAAGGTCTCGACGGAGTACGGCGGTAAGAGCCAGCTGAACCTCGGCCATCTCGTGGATGCTGAAAAGC
AGCCGCGCGGCGAAGGCTTTGAGCTGAGAACCGACAGCTGGGGCGCTATCCGGGCACAGAAAGGGATATTTATCAGCGCG
GACGGACAGGTGCAGGCTCAGGGGCAGGTGCTGGATATGGAGCCGGCGGTCAGCAATCTGGCCGAAGCCCGGGAGCAGAT
GATGTCCATCTCCGGTGACGCGCAGAAGGCGACCGCGAACCCGGCCGATCTCCAGGCGCAAATTACCCTGCTGGAGCAGC
AGCTGACAGACCTCAAAAAATCGGTACTGCTGGTCAGCGCGCCGGAGGGGATAGCGCTGACCAGCGGGGAGCACCTGCAG
GTCTCAGCCGGGCATAACCTGATTGCCACAGCCGGAAAGAATGCAGACGTCAGCGTGGTGAAAAATCTGTTCATCGGGGT
GGGCAGTGCGCTGAGCGTGTTTGTGCGAAAGCTTGGGATCAGGCTGATAGCGAATCAGGGACCGGTACAGATGCAGGCGC
AGAATGACCTGATGGCGCTGCTTGCCCGGAAGGAAATCAGCATTGTCAGCACGGAGGATGAAATCAAAATCATCGCGAAG
AAGAAGCTGACCCTGAATGGTGGGGGGAGTTATATCAGACTTGATGCAAATGCGATTGAATCTGCTACTGCAGGCGAATA
TCGCACGAAAGCAGGATATTACGGGCGTCAGGAAAGCGCTTCTGAAAAAGTCAAAATGCCTGTATTTCCTGTAATGGAGC
CTGGAGAGCACAGTTTACGTTTTGCTTTTCCAGGTGCGGATAGTGTCAGCCAGAGTATGAACTGGCTGATAAATCAGCCG
TACAGTATTTCTGATAGCGCTGGAAAAATTCTGTCTACCGGAACAGTAGACACTTCAGGTCGTTTTCCCAAAATAGTACT
TCCTGAAAGCGATACATTAAATTTAATCATTGGCCGAGAAACTTGGAGTAAAGAGGAGCTTTCTGTCTCATCAACTGAAG
ACGACAGTATGGAGGATTTTGAGGATGAAGCACCTGATGCCGATCTTCATTTAAGTGAAATGGGTTTTGAAGATGATAGA
ACATCAGCATTGACTGAATCAATGATTTCAACTTTATTAAGTTTAACAAAGGATAGTTGA