Detailed information of component protein


Summary

Component ID T6CP003500
Component protein type TssH
T6SS ID (Type) T6SS00344 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (885 a.a.); Nucleotide sequence (2655 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KP1_RS11250
Coordinate (Strand) 2305440..2308094 (+)
NCBI ID WP_015874721.1
RefSeq NC_012731
Uniprot ID A0A652Q198_9ENTR, A0A332IKV4_KLEPN, A0A3F3B5V2_KLEPN
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
AAA_2 PF07724.16 2.7e-38 610..775
AAA_lid_9 PF17871.3 1.3e-30 378..468
ClpB_D2-small PF10431.11 1.9e-12 784..855
AAA PF00004.31 5.2e-09 238..350
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-884 MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSVRHRPQLSHHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRPLLDAQSDERPPAQQEAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGLIDPVFGRDTEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALCIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHITDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPEPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLAAIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEISDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVPLSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTETALALADALFGGEKALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREIDFRNTVILMTANLGSDLLMQLLDEQPEASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQRLACHYGITTTLSESLFDALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGTISDE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8846 - -


  Protein sequence: 885 a.a.    

>T6CP003500 NC_012731:2305440-2308094 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssH]
MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSV
RHRPQLSHHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRPLLDAQSDERPPAQQ
EAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGLIDPVFGRDTEIRQMVDILSRRRKNNPILV
GEPGVGKTALVEGLALCIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIG
AGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHI
TDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPEPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLA
AIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEISDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVP
LSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTETALALADALFGGEK
ALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREI
DFRNTVILMTANLGSDLLMQLLDEQPEASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQR
LACHYGITTTLSESLFDALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGT
ISDE*

  Nucleotide sequence: 2655 bp    

>T6CP003500 NC_012731:2305440-2308094 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssH]
ATGGAAAATCCAGCCAGCCTGTTACGCCGTCTTAATCCCTGCTGTGCCCGCGCAATGGAGGGGGCGGCCTCCCTGTGCCA
GACCCGGGCGCATGCCGAGATCCTGCCCGAGCACTGGCTGCTCAAGCTGCTGGAACAGGGGGAAGGCGATCTGACGGTGC
TGGCGCGGCGCTATGAATGGGATATGGATGCGCTGTGGCAGGATCTGCTGAGCTGGCTGGATAAACAGCCGCGCTCGGTA
CGTCATCGTCCCCAGCTCTCTCACCATACCCTGAGGCTGATGCAGGAGGCCTGGCTGATTGCCTCTCTCAGCGGCGAAGC
GCAGATCCGCAGTGTTCACCTGCTGATGGCGCTGGTTGAAAAACAGAATCTGATCCAGTGCGATGGCCTGTGGCCGCTGT
TAACGCTGGGCCAGCGTCAGCTGGAACGCCTGCGCCCCTTGCTGGATGCCCAGTCCGACGAACGTCCGCCAGCGCAGCAG
GAAGCGGCGCTTGCGCAGCCCCATGGCGGGGACGTGGAATTTGTGGGGCGTCCCGCGGGCAGCGAACTGAATGCGGATGG
GCTCAACCCGGCGCTGCAGAACGCGCTGGACAAATTCACTCTCGACGTCACCGCCAAAGCCAGAGACGGCCTGATTGACC
CGGTGTTCGGACGTGACACGGAAATCCGCCAGATGGTGGATATTCTCTCCCGTCGACGTAAAAACAACCCGATCCTCGTC
GGTGAGCCGGGCGTGGGCAAGACCGCTCTGGTGGAAGGCCTGGCGCTGTGCATTGCCGAAGGCAACGTCCCCGACGCGCT
GAAGCCGGTGTCGGTGCGCACCCTCGACCTCGGTCTGCTGCAGGCCGGCGCCGGGGTCAAAGGCGAGTTCGAGCAGCGGC
TGAAAAATATCATTGAGGCGGTACAGCAGTCGCCTTCGCCGGTGCTGCTGTTTATCGACGAGGCGCACACGATCATCGGC
GCGGGTAATCAGGCGGGCGGCGCGGATGCCGCCAACCTGTTGAAGCCGGCTCTGGCCCGGGGCGAGCTGCGGACCATCGC
CGCCACCACCTGGAGTGAATACAAGCAGTACTTCGAGCGCGACGCCGCGCTGGAGCGCCGCTTTCAGATGGTCAAGGTGG
ATGAGCCGGACGACGACACCGCCTGCCTGATGCTGCGCGGCCTGAAGTCCCGCTATGCCGACCACCACGGCGTGCATATC
ACGGATGATGCGGTGCGCGCCGCCGTGACGCTGTCACGACGCTATCTCACCGGTCGCCAGCTGCCGGACAAGGCAGTGGA
TTTACTCGACACCGCTTCCGCCCGCCTGCGTATGAGTTTGGATACCGTGCCTGAGCCGCTGACCCGCATGAAGGCGCAGC
TCACCGCGCTGGCGATGGAGAAGCAGGCGCTGCTGGAAGATATTGCGCTGGGCAACAGCGCCCGCGGCGATCGGCTGGCG
GCCATTGAGCAGGAGGAGATCCGTCTTATTCTGGCGCTGGATACCCTTGAAACTCAGTATGGTCAGGAGCTGCAGCTGAC
GGAAGCGCTGCTCGCCTGCCGCCGCGATATCTCCCGCCAGGCGGAAATTAGCGATCTACAAACCGCGCTTATCGCCGTCC
AGCAGGGCAATCCGCTGCTCGGGCTGGACGTCGACGTCCGCACCGTGGCGACGGTGATTGCCGACTGGACCGGCGTGCCG
CTCTCCTCGCTAATGAAAGATGAGCAGACGGAGCTGCTGAGTCTGGAAGAGAGTCTCGGCAAACGGGTGGTTGGCCAGGA
GGCGGCCCTGAGCGCTATTGCCCGGCGCCTGCGCGCCGCGAAAACCGGCCTGACGCCGGAGAACGGTCCGCAAGGGGTGT
TCCTGCTGGTCGGGCCGAGCGGCACCGGCAAAACGGAAACGGCGCTCGCCCTGGCCGATGCGCTGTTCGGCGGCGAGAAA
GCGCTGATCACCATCAATCTCTCCGAGTACCAGGAGCCGCACACCGTCAGCCAGCTGAAGGGTTCTCCGCCCGGCTACGT
CGGCTACGGCCAGGGCGGGATCCTGACCGAGGCGGTGCGCAAACGCCCCTACAGCGTGGTGCTGCTCGATGAGGTGGAAA
AGGCCCATCGCGATGTGATGAACCTGTTCTACCAGGTCTTCGACCGGGGGGTAATGCGCGACGGCGAGGGGCGTGAAATC
GACTTTCGCAACACCGTGATCCTGATGACCGCCAACCTCGGAAGCGACCTCCTGATGCAGTTGCTGGATGAACAGCCGGA
GGCCAGCGAATCAGACCTGCACGAGCTGCTGCGCCCGGTGCTGCGCGGCCACTTCCAGCCGGCGCTGCTGGCCCGCTTCC
AGACGGTGATTTACCGTCCGCTGCCGGCGGGAGCGCTGCGCGCCATTGTCGGCATGAAGCTCGGGCAGGTAAGTCAGCGT
CTGGCTTGCCATTACGGAATCACCACCACCCTCAGCGAGAGCCTGTTCGACGCGCTGACCGAGGCCTGCCTGCTGCCGGA
TACCGGCGCCCGTAACGTCGACAGTCTGCTCAATCAGCAGATCCTGCCGGCACTGAGTCAGCAGCTATTGAGCCATATGG
CGGCGGGGCAGAAACCGCGCCAGGTGACGCTGGGGTATCACGAAGAGGAAGGCGTCGTGATGGCGTTTGACGAGGGGACA
ATATCCGATGAGTAG