SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP003063
Component protein type	TssB
T6SS ID (Type)	T6SS00301 (Type i3)
Strain	Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853
Replicon	chromosome
Sequence	Protein sequence (181 a.a.); Nucleotide sequence (543 bp)
Reference	[1] Blondel CJ, Jiménez JC, Contreras I, et al. Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 2009 Aug 4;10:354. doi: 10.1186/1471-2164-10-354. PMID: 19653904 [2] Pezoa D, Blondel CJ, Silva CA, et al. Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts. Vet Res. 2014 Jan 9;45:2. doi: 10.1186/1297-9716-45-2. PMID: 24405577

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	SED_RS01830
Coordinate (Strand)	314723..315265 (+)
NCBI ID	WP_000996817.1
RefSeq	NC_011205
Uniprot ID	A0A3Z2NTP6_SALEN, A0A606UHN8_SALTM, A0A7U1KS07_SALET, A0A0H3ND31_SALTS, A0A3Z3GFK8_SALET, A0A4P9T0F1_SALET, A0A5I4KMM1_SALET, A0A3U8PAI7_SALBE, A0A0M0PTI9_SALER, A0A5W1RH43_SALET, A0A2T8QKQ0_SALET, A0A3T2WCQ2_SALET, A0A6C6ZZQ9_SALDC, A0A315GLS2_SALET, A0A6C7I6R3_SALTD, A0A6Y0YUC8_SALET, A0A0F6AX74_SALT1, A0A3U7NHJ4_SALET, A0A636DDZ3_SALET, A0A5R1YIV3_SALIN, A0A3V6BQG0_SALTH, A0A4U1FYX3_SALET, H9L4I8_SALTM, E8XIT7_SALT4, A0A5H9CY08_SALDU, A0A3Z6P2N8_SALTU, Q93IS8_SALTY
KEGG ID	seb:STM474_0284, sev:STMMW_02731, seni:CY43_01370, sey:SL1344_0267, sed:SeD_A0296, stm:STM0273, seo:STM14_0320, sej:STMUK_0275
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_VipA	PF05591.14	5.2e-57	12..162

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-180	MAINNSAQKFIARNRAPRVQIEYDVEIYGSEKKIELPFVMAVLADLAGKPREELPPVTDRKFLDIDIDNFNERMKAIAPRVAFAVPNTLTGEGQLMVDITLENMDDFSPAQIARKVDALNQLLEARTQLANLQTYMDGKAGAENLVNKLLQDPTLLKTLANAPKSAATQQDVSADNESAE

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9970	-	-

Protein sequence: 181 a.a.

						>T6CP003063 NC_011205:314723-315265 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [TssB]
MAINNSAQKFIARNRAPRVQIEYDVEIYGSEKKIELPFVMAVLADLAGKPREELPPVTDRKFLDIDIDNFNERMKAIAPR
VAFAVPNTLTGEGQLMVDITLENMDDFSPAQIARKVDALNQLLEARTQLANLQTYMDGKAGAENLVNKLLQDPTLLKTLA
NAPKSAATQQDVSADNESAE*					

Nucleotide sequence: 543 bp

						>T6CP003063 NC_011205:314723-315265 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [TssB]
ATGGCTATCAACAATAGCGCGCAGAAATTCATCGCGCGCAACCGCGCGCCGCGCGTGCAGATTGAATATGACGTAGAGAT
TTACGGTTCCGAGAAAAAAATCGAGCTGCCGTTCGTGATGGCGGTGCTGGCCGATCTGGCCGGGAAACCGCGTGAAGAAC
TGCCGCCGGTGACGGATCGCAAATTCCTCGATATTGATATTGATAACTTCAATGAGCGCATGAAAGCCATTGCGCCGCGC
GTGGCGTTCGCTGTGCCGAATACGCTGACGGGTGAAGGTCAGTTGATGGTCGATATCACGCTGGAAAATATGGACGACTT
TTCGCCGGCACAGATTGCCCGCAAGGTGGACGCCCTGAACCAGTTACTGGAAGCCCGCACTCAACTGGCGAACCTCCAGA
CCTACATGGATGGCAAGGCCGGGGCGGAAAATCTGGTCAATAAACTGTTGCAGGACCCGACTCTGCTGAAAACGCTGGCG
AATGCGCCGAAATCGGCCGCTACCCAGCAAGATGTGTCAGCGGATAATGAATCAGCGGAATAA					