Detailed information of component protein


Summary

Component ID T6CP002717
Component protein type TssM
T6SS ID (Type) T6SS00272 experimental (Type i1)
Strain Proteus mirabilis HI4320
Replicon chromosome
Sequence Protein sequence (1183 a.a.); Nucleotide sequence (3549 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) PMI_RS03620
Coordinate (Strand) 811475..815023 (-)
NCBI ID WP_004244610.1
RefSeq NC_010554
Uniprot ID B4ET48_PROMH, A0A1Z1SY45_PROMI
KEGG ID pmr:PMI0736
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 3.2e-68 515..827
IcmF-related_N PF14331.8 3e-60 214..463
IcmF_C PF06744.14 2.9e-18 1056..1158
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-25 MKLPVFSISNITSSVKKLFFADKSK
Transmembrane helix 26-48 IASFLLFLLALLPALLIIWIWWW
Outside 49-62 GPTFRYQDSIPFSE
Transmembrane helix 63-85 VTTRWLATVVIVLLVVSWIGLAT
Inside 86-458 WRRVKKLEALKLDVELAVVDPVRQDLDFQKRYLNYWKSQFIRHLNGHTKAVYLRPWYFVLGANQSGKHSLLKNTVNPLDIAPSDNIVNEQNIALNIQCLLTDNAVLFVPNGDLLTQPANQADKPQLYHRLWGDLLNWIKTNRPRQPMNGIVLTVDTLSLLTNSKEQNSQLLADLQMRIEEIRMTFNSRLPLYIVLTKLDLLRGFDSMYQSLDVQQRNEVLGVSFNQKAKSNWKKELNHFWSQWVGQMNSALPEMMLQRAEGNQRSDLFSFVRQIEGLQHSVCTLIDALLINNEQHNICLRGVYLTSALQIGQIDDVFSQTASEQYHLPTAPLTTWPINDSHPYFTTQLFSQVLFSEPNIAAENHYWVKKHRTR
Transmembrane helix 459-481 LLVTTAVSFVGLIAIWNGWSHYY
Outside 482-1182 DKNYRAGENVLNEVKAFRAIENNAQKDTDGSLQLPVLNPLREATLAYGNHRDKNVLFSDMGLYQGQKVGPQVEQVYLQLLTDRFLPAVMSGLLNELNSADKGSEDKLEILRIMRMLEDKSGRNNGMVEDFMADYWSQLFTGQREKQLQLKAHLRYALEHTDWKQEREKGFVSATKAFMPFAGPIKNAQAELSVLSLYQRVYQALRLKANQELSAPLNLQHQIGPSFNTVFTAIDDDKLEIPQFLTRSGLLNYFIRQNDKLVELTLLDAWVLNLTTNTQYSESDRKEIQRQISEQYLSDYTAQWRNAMSNLEIRQFDSIQDEITALEQIISGEQPLRRALQVLRDNTVIPTIDENLPLDEQKTLMAEPSYRLLTRLDREFTPQTEILVSNQGENLQNLNQKLNDLHRYLLGIQNSPVPGKAALKAVSMRLNDNNRDAIFELSQMAKTLPEPLNRWVDELSVQAWNVVQKEAIRYMEVEWNENVVKQYNTYIAGRYPFNPAAKQDVPLSEFERFFKPNGTLDSFYQQNLRLFVENNLVNDSDSQSLIRADVLAQIEIANRIRETFFNAQGNLEAQYAIEPLSLSGNKRRSILNLDGQLIDYAHSRSHVTHLVWPNSMRSNIESKLTLVPLSGDKSPRSISFSGPWAQMRLVDNAKLINIKSNSFDIRFTIDGGDMTYRVIVDESNNPFFGGLFTKFRLPETLY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9935 - -


  Protein sequence: 1183 a.a.    

>T6CP002717 NC_010554:c815023-811475 [Proteus mirabilis HI4320] [TssM]
MKLPVFSISNITSSVKKLFFADKSKIASFLLFLLALLPALLIIWIWWWGPTFRYQDSIPFSEVTTRWLATVVIVLLVVSW
IGLATWRRVKKLEALKLDVELAVVDPVRQDLDFQKRYLNYWKSQFIRHLNGHTKAVYLRPWYFVLGANQSGKHSLLKNTV
NPLDIAPSDNIVNEQNIALNIQCLLTDNAVLFVPNGDLLTQPANQADKPQLYHRLWGDLLNWIKTNRPRQPMNGIVLTVD
TLSLLTNSKEQNSQLLADLQMRIEEIRMTFNSRLPLYIVLTKLDLLRGFDSMYQSLDVQQRNEVLGVSFNQKAKSNWKKE
LNHFWSQWVGQMNSALPEMMLQRAEGNQRSDLFSFVRQIEGLQHSVCTLIDALLINNEQHNICLRGVYLTSALQIGQIDD
VFSQTASEQYHLPTAPLTTWPINDSHPYFTTQLFSQVLFSEPNIAAENHYWVKKHRTRLLVTTAVSFVGLIAIWNGWSHY
YDKNYRAGENVLNEVKAFRAIENNAQKDTDGSLQLPVLNPLREATLAYGNHRDKNVLFSDMGLYQGQKVGPQVEQVYLQL
LTDRFLPAVMSGLLNELNSADKGSEDKLEILRIMRMLEDKSGRNNGMVEDFMADYWSQLFTGQREKQLQLKAHLRYALEH
TDWKQEREKGFVSATKAFMPFAGPIKNAQAELSVLSLYQRVYQALRLKANQELSAPLNLQHQIGPSFNTVFTAIDDDKLE
IPQFLTRSGLLNYFIRQNDKLVELTLLDAWVLNLTTNTQYSESDRKEIQRQISEQYLSDYTAQWRNAMSNLEIRQFDSIQ
DEITALEQIISGEQPLRRALQVLRDNTVIPTIDENLPLDEQKTLMAEPSYRLLTRLDREFTPQTEILVSNQGENLQNLNQ
KLNDLHRYLLGIQNSPVPGKAALKAVSMRLNDNNRDAIFELSQMAKTLPEPLNRWVDELSVQAWNVVQKEAIRYMEVEWN
ENVVKQYNTYIAGRYPFNPAAKQDVPLSEFERFFKPNGTLDSFYQQNLRLFVENNLVNDSDSQSLIRADVLAQIEIANRI
RETFFNAQGNLEAQYAIEPLSLSGNKRRSILNLDGQLIDYAHSRSHVTHLVWPNSMRSNIESKLTLVPLSGDKSPRSISF
SGPWAQMRLVDNAKLINIKSNSFDIRFTIDGGDMTYRVIVDESNNPFFGGLFTKFRLPETLY*

  Nucleotide sequence: 3549 bp    

>T6CP002717 NC_010554:c815023-811475 [Proteus mirabilis HI4320] [TssM]
ATGAAATTACCGGTTTTCTCCATTTCAAACATTACGAGTTCGGTAAAAAAACTCTTTTTTGCTGATAAATCTAAAATTGC
CTCCTTTTTGCTATTTTTATTGGCATTACTTCCCGCTTTGCTCATTATTTGGATCTGGTGGTGGGGGCCAACATTTCGTT
ATCAAGATTCCATACCGTTTAGCGAGGTCACCACACGTTGGTTAGCAACCGTCGTTATTGTATTGCTTGTTGTGAGTTGG
ATTGGTCTAGCAACATGGCGTCGAGTTAAAAAATTGGAAGCATTAAAACTTGATGTCGAATTGGCTGTAGTTGATCCGGT
AAGACAAGATCTTGATTTTCAAAAACGTTATTTAAACTATTGGAAATCACAATTTATTCGCCACTTAAATGGTCATACTA
AAGCGGTTTATTTACGCCCTTGGTATTTTGTTTTAGGTGCTAACCAAAGTGGAAAGCATAGCTTATTAAAAAATACGGTA
AACCCATTAGATATTGCGCCTAGCGACAATATTGTTAACGAACAAAATATTGCATTAAATATTCAATGTCTATTAACCGA
CAATGCTGTACTTTTTGTCCCTAATGGTGATCTATTAACCCAGCCGGCAAATCAGGCTGATAAACCTCAACTTTATCACC
GTTTGTGGGGCGATTTACTCAATTGGATCAAAACTAATCGCCCAAGACAACCAATGAATGGCATCGTCTTAACTGTCGAT
ACCCTATCGTTATTAACCAATAGTAAGGAGCAAAATAGTCAGCTACTTGCTGATTTACAAATGCGTATTGAAGAAATACG
CATGACATTTAATAGTCGCTTGCCTTTATATATCGTCTTAACCAAGCTAGATCTATTACGTGGTTTTGACTCAATGTATC
AATCATTAGATGTTCAACAACGTAATGAAGTACTAGGTGTTTCTTTCAACCAGAAAGCAAAAAGTAATTGGAAAAAGGAA
TTAAATCATTTTTGGTCACAATGGGTAGGCCAAATGAACAGCGCATTACCAGAAATGATGCTACAAAGAGCAGAAGGTAA
CCAGCGTAGTGATCTATTTAGTTTCGTGCGCCAAATTGAAGGGTTACAACATTCTGTATGCACATTAATTGATGCATTGC
TCATCAATAATGAGCAACATAATATCTGTTTAAGAGGGGTTTATTTAACTTCTGCATTGCAAATCGGTCAAATCGATGAT
GTGTTTAGCCAAACAGCGTCCGAACAATATCATTTACCGACAGCACCTCTTACTACATGGCCAATTAATGATAGCCACCC
TTATTTTACTACCCAATTATTTAGTCAAGTGCTATTTAGTGAGCCTAATATTGCAGCAGAAAACCATTATTGGGTTAAAA
AACATCGGACTCGCCTATTAGTCACCACTGCTGTTAGCTTTGTCGGCTTAATCGCAATTTGGAATGGTTGGAGCCACTAT
TACGACAAAAACTATCGTGCTGGAGAAAACGTTCTTAATGAGGTAAAAGCATTCCGTGCTATTGAGAACAATGCTCAGAA
AGATACTGATGGTAGCCTACAATTACCGGTGCTCAATCCATTACGTGAAGCAACCTTAGCTTATGGTAATCATCGTGATA
AAAATGTGCTCTTTTCTGATATGGGTCTTTACCAAGGTCAAAAAGTTGGCCCACAAGTTGAACAAGTCTATTTACAACTA
CTCACCGATCGTTTTTTACCTGCGGTTATGTCTGGGTTGTTAAATGAACTTAACAGTGCCGACAAAGGAAGTGAAGATAA
GTTAGAGATATTGCGTATTATGCGCATGTTAGAAGATAAAAGTGGCCGTAATAATGGCATGGTAGAAGATTTTATGGCCG
ATTATTGGAGCCAACTGTTCACTGGTCAACGTGAAAAACAACTGCAACTAAAAGCCCATTTGCGCTATGCCCTTGAGCAC
ACAGATTGGAAACAAGAGCGTGAAAAAGGATTTGTTTCAGCCACTAAAGCCTTTATGCCTTTTGCTGGACCTATAAAAAA
TGCACAAGCAGAGTTAAGTGTATTGTCACTTTATCAGCGTGTATATCAAGCCTTACGCTTAAAGGCTAATCAAGAGCTTT
CAGCGCCTTTAAATTTACAACATCAAATTGGCCCAAGTTTTAATACGGTCTTTACGGCTATTGATGATGATAAATTAGAA
ATTCCACAATTCTTAACGCGCTCAGGGTTATTAAACTATTTTATCCGCCAAAATGATAAATTGGTCGAGCTAACATTACT
TGATGCTTGGGTTCTTAATCTAACCACCAACACACAATATAGTGAAAGTGATCGTAAAGAAATTCAGCGTCAAATCAGTG
AACAATATCTTAGTGACTATACGGCTCAATGGCGTAATGCCATGAGCAATTTAGAAATTCGTCAATTTGATTCAATACAA
GATGAAATTACCGCTCTTGAGCAAATTATTAGTGGTGAACAACCATTACGCCGAGCATTACAAGTTCTACGTGATAACAC
GGTTATTCCAACTATTGATGAAAATTTACCACTTGATGAACAAAAAACACTGATGGCTGAGCCATCTTACCGTTTATTAA
CCCGCTTAGATCGCGAATTTACTCCTCAAACTGAGATATTAGTCAGTAACCAAGGGGAAAATTTACAGAATCTGAATCAA
AAACTAAATGACTTACATCGTTACCTATTGGGGATCCAAAACTCTCCAGTGCCGGGGAAAGCGGCGCTTAAAGCAGTTTC
GATGCGCTTAAACGATAATAATCGCGACGCTATTTTTGAGCTATCACAAATGGCGAAAACATTACCAGAGCCGCTTAACC
GCTGGGTCGATGAGTTATCAGTGCAAGCATGGAATGTGGTCCAAAAAGAAGCTATTCGTTATATGGAAGTAGAATGGAAT
GAAAATGTTGTCAAACAATACAATACTTATATTGCCGGTCGCTATCCATTTAACCCAGCAGCTAAACAAGATGTTCCTTT
AAGTGAATTTGAACGTTTCTTCAAACCAAATGGAACATTAGATAGCTTCTATCAACAAAATCTGCGTTTATTCGTTGAGA
ATAACTTAGTTAACGATAGTGATAGCCAATCATTGATCCGCGCTGATGTATTAGCACAAATTGAAATAGCCAATCGTATT
AGAGAAACCTTCTTTAATGCCCAAGGTAATTTAGAAGCACAATATGCTATTGAGCCACTGTCATTAAGTGGTAATAAGCG
TCGTAGCATCTTAAATCTTGATGGACAATTGATTGATTACGCTCATAGTCGCAGCCATGTGACACACTTGGTATGGCCAA
ACTCAATGCGTTCCAATATTGAAAGTAAACTGACTTTAGTGCCTCTTTCCGGTGATAAATCGCCACGTTCAATCAGTTTC
TCTGGGCCATGGGCACAAATGCGATTAGTTGATAATGCAAAACTCATCAATATCAAATCTAACTCATTCGATATTCGCTT
CACAATCGACGGTGGTGATATGACTTATCGAGTTATAGTTGATGAATCTAATAATCCTTTCTTCGGTGGATTATTCACAA
AATTCCGTTTACCTGAAACGCTTTATTAA