SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP002537
Component protein type	TssI
T6SS ID (Type)	T6SS00256 (Type i1)
Strain	Yersinia pseudotuberculosis YPIII
Replicon	chromosome
Sequence	Protein sequence (741 a.a.); Nucleotide sequence (2223 bp)
Reference	[1] Zhang W, Xu S, Li J, et al. Modulation of a thermoregulated type VI secretion system by AHL-dependent quorum sensing in Yersinia pseudotuberculosis. Arch Microbiol. 2011 May;193(5):351-63. doi: 10.1007/s00203-011-0680-2. Epub 2011 Feb 5. PMID: 21298257 [2] Zhang W, Wang Y, Song Y, et al. A type VI secretion system regulated by OmpR in Yersinia pseudotuberculosis functions to maintain intracellular pH homeostasis. Environ Microbiol. 2013 Feb;15(2):557-69. doi: 10.1111/1462-2920.12005. Epub 2012 Oct 24. PMID: 23094603

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	YPK_RS02010
Coordinate (Strand)	439588..441810 (+)
NCBI ID	WP_012303457.1
RefSeq	NC_010465
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
Phage_GPD	PF05954.13	1.3e-82	134..431
Phage_base_V	PF04717.14	5.9e-14	489..555

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-740	MFAHDKANNNKAADKTGTVTPTHIVSPEAAPTVSGAQMTEIAGGIGDAVGGTAGKRINQAAEVAKTALDAKAKVLDGGVTPLNLAAGGAGAGLPDSVAAALTRLVKQPSGLQFTLTAAGLPPQTFAVVDFTLSEMLSSPFVLNVGLASADPAVDFAAVLDEDATLFIWREGVLQRSITGMVASFEQGDTGFHQTRYSMVIRPALWRTSLRRNARIFQQASVEEIITTLLKENGINDFAFGFRHPHPVREFCVQYQESDFDFIQRLTAEEGIFYYFEFSAGKNTVVYADDVGSLPKGASLPYNPNVAAQAQELSITTFTRSAQVRPAMVQLKDYTFKNPNWAAAFSEQSGELQNQRPDYEHFDFPGRFKDAQHGQDFTRYRLDALRNDANLGQGASNDFTLQPGQLFSLYNHPRSDLNHAWQLLGIQHSGKQMQALEQASGDQGTVLFNHFSFIPHTQTWRPTPLAKPAMDGPQIAMVVGPPGEEIYCDEYGRIRLQFLWDRYGQSNDNSSCWIRVTQPWAGQGWGMLAIPRIGQEVVVDFLHGDPDQPIVTGRTYHANNIPPGSLPASKTQMAFRSKTHKGEGYNEMRFEDAKGGEGLFMHAQKDMTTMVLNDRKTDVTQDHSEHIGQDQSVTVVRNQSNTIQNDRRVEVTRDQQTEVGNDYQLVVKGEKKEFVTKIRYTEVHEDETLTVTKSIKIHAKQGDISISTPNAGITITHDGAIILQGKYIRLAADMIDLNPEE

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9490	-	-

Protein sequence: 741 a.a.

						>T6CP002537 NC_010465:439588-441810 [Yersinia pseudotuberculosis YPIII] [TssI]
MFAHDKANNNKAADKTGTVTPTHIVSPEAAPTVSGAQMTEIAGGIGDAVGGTAGKRINQAAEVAKTALDAKAKVLDGGVT
PLNLAAGGAGAGLPDSVAAALTRLVKQPSGLQFTLTAAGLPPQTFAVVDFTLSEMLSSPFVLNVGLASADPAVDFAAVLD
EDATLFIWREGVLQRSITGMVASFEQGDTGFHQTRYSMVIRPALWRTSLRRNARIFQQASVEEIITTLLKENGINDFAFG
FRHPHPVREFCVQYQESDFDFIQRLTAEEGIFYYFEFSAGKNTVVYADDVGSLPKGASLPYNPNVAAQAQELSITTFTRS
AQVRPAMVQLKDYTFKNPNWAAAFSEQSGELQNQRPDYEHFDFPGRFKDAQHGQDFTRYRLDALRNDANLGQGASNDFTL
QPGQLFSLYNHPRSDLNHAWQLLGIQHSGKQMQALEQASGDQGTVLFNHFSFIPHTQTWRPTPLAKPAMDGPQIAMVVGP
PGEEIYCDEYGRIRLQFLWDRYGQSNDNSSCWIRVTQPWAGQGWGMLAIPRIGQEVVVDFLHGDPDQPIVTGRTYHANNI
PPGSLPASKTQMAFRSKTHKGEGYNEMRFEDAKGGEGLFMHAQKDMTTMVLNDRKTDVTQDHSEHIGQDQSVTVVRNQSN
TIQNDRRVEVTRDQQTEVGNDYQLVVKGEKKEFVTKIRYTEVHEDETLTVTKSIKIHAKQGDISISTPNAGITITHDGAI
ILQGKYIRLAADMIDLNPEE*					

Nucleotide sequence: 2223 bp

						>T6CP002537 NC_010465:439588-441810 [Yersinia pseudotuberculosis YPIII] [TssI]
ATGTTTGCTCATGATAAAGCTAATAATAATAAAGCCGCGGACAAGACCGGCACGGTGACGCCGACCCATATCGTCTCGCC
GGAGGCCGCCCCAACCGTGAGTGGCGCTCAGATGACCGAGATAGCCGGGGGGATCGGGGATGCGGTGGGCGGCACTGCCG
GTAAGCGCATCAATCAGGCCGCCGAGGTGGCTAAAACTGCCCTGGATGCCAAGGCAAAAGTACTGGACGGCGGCGTCACG
CCGCTGAATCTGGCCGCGGGCGGGGCCGGGGCGGGATTGCCGGACAGCGTGGCGGCGGCGCTTACCCGCCTGGTCAAACA
GCCCTCAGGCCTGCAATTTACCCTGACGGCGGCCGGTTTACCGCCCCAGACCTTTGCGGTGGTGGATTTCACCCTGAGCG
AGATGCTCTCCTCGCCGTTTGTGCTCAATGTCGGGCTGGCGAGTGCCGATCCGGCGGTGGATTTTGCGGCGGTATTGGAT
GAAGACGCCACGCTGTTTATCTGGCGAGAAGGGGTACTGCAACGCAGCATCACCGGCATGGTCGCCAGCTTTGAACAGGG
TGATACCGGTTTTCATCAGACCCGCTACAGCATGGTGATCCGCCCGGCGCTGTGGCGCACCAGCCTGCGGCGCAATGCCC
GCATCTTCCAGCAGGCCTCGGTGGAAGAGATCATCACCACCCTGCTGAAAGAGAACGGCATCAACGATTTTGCTTTTGGT
TTTCGCCACCCGCACCCGGTGCGCGAGTTCTGCGTGCAATATCAGGAGTCCGATTTTGATTTTATCCAGCGCCTGACGGC
AGAAGAGGGGATTTTCTACTACTTCGAGTTCAGCGCCGGGAAAAATACCGTGGTGTATGCCGATGATGTTGGCTCCCTGC
CGAAAGGCGCGTCACTGCCCTATAACCCGAATGTGGCGGCGCAGGCGCAGGAACTGAGTATCACCACCTTCACCCGCAGT
GCGCAGGTGCGCCCGGCGATGGTGCAACTGAAAGACTACACCTTTAAAAACCCGAACTGGGCCGCGGCCTTCAGCGAACA
GTCGGGAGAACTGCAAAACCAGCGACCGGACTACGAGCATTTTGATTTTCCGGGGCGCTTCAAAGATGCCCAGCACGGGC
AGGATTTTACCCGCTACCGGCTGGACGCACTGCGCAATGACGCCAATCTGGGGCAGGGGGCGAGCAATGATTTTACCCTC
CAGCCGGGGCAGTTGTTCAGCCTGTACAACCACCCACGTAGTGACCTGAACCACGCCTGGCAGTTGCTCGGTATTCAGCA
CAGCGGCAAACAGATGCAGGCGCTGGAGCAGGCATCTGGCGATCAGGGCACGGTGCTGTTCAACCACTTCAGTTTTATTC
CGCACACCCAGACCTGGCGGCCGACGCCGTTGGCTAAACCGGCGATGGACGGCCCGCAGATCGCCATGGTGGTGGGGCCA
CCGGGGGAAGAGATTTACTGCGACGAATACGGCCGTATCCGCCTGCAATTTTTATGGGATCGCTACGGGCAGAGCAATGA
CAACAGCTCCTGCTGGATCCGGGTAACCCAGCCGTGGGCGGGCCAGGGCTGGGGCATGCTGGCCATTCCGCGTATTGGCC
AGGAAGTGGTGGTGGATTTTCTGCACGGCGATCCGGATCAACCGATTGTCACGGGGCGGACCTATCACGCCAACAACATC
CCGCCGGGGTCGTTACCGGCCAGTAAAACCCAGATGGCGTTCCGCTCAAAAACCCACAAAGGGGAAGGCTACAACGAAAT
GCGCTTCGAGGATGCCAAAGGCGGCGAAGGGCTGTTTATGCATGCGCAGAAAGATATGACGACCATGGTGCTGAATGATC
GCAAAACCGATGTGACTCAGGACCATTCAGAGCACATTGGGCAAGACCAGTCCGTGACGGTTGTGCGTAACCAAAGTAAT
ACGATCCAAAATGATCGCCGGGTGGAGGTGACTCGCGATCAACAAACCGAAGTGGGCAATGATTACCAGCTAGTGGTGAA
AGGTGAAAAGAAAGAGTTTGTGACGAAAATTCGTTACACCGAAGTGCATGAAGACGAAACGCTCACGGTGACGAAAAGTA
TTAAAATCCATGCCAAACAAGGTGATATCAGCATATCAACCCCGAATGCCGGAATTACGATCACCCATGACGGTGCCATT
ATTCTGCAAGGGAAATACATTCGTTTAGCGGCCGATATGATCGATCTTAATCCAGAGGAGTAG					