Detailed information of component protein


Summary

Component ID T6CP002536
Component protein type TssM
T6SS ID (Type) T6SS00256 insolico (Type i1)
Strain Yersinia pseudotuberculosis YPIII
Replicon chromosome
Sequence Protein sequence (1178 a.a.); Nucleotide sequence (3534 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) YPK_RS02000
Coordinate (Strand) 434601..438134 (+)
NCBI ID WP_012104359.1
RefSeq NC_010465
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 1.3e-76 508..821
IcmF-related_N PF14331.8 2.5e-70 203..452
IcmF_C PF06744.14 3.1e-22 1050..1154
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-19 MKLPFFIRIAKPAIPRLKA
Transmembrane helix 20-39 SIPVVLALMACAALIWVWIY
Outside 40-53 GPEWQLGENYPFET
Transmembrane helix 54-76 LLSRWLVTAVFVLVAVCWLSLKV
Inside 77-452 MRRVQHLEKLQLQTKIQLDDPVSADIEQQNHYLNGWKHQLQRHLNTPEYLYHLPWYMVIGARNSGKSTLIKEGYKLTEISASERLHVEGAADLRVRCWLGEQAVIIDPAGVLIEQPTTPIAGKASLNSRLWQSLLSWLIEQRQRQPLNGIILTVDLHQMMTANKAQRETYVADIHQRLQEIRLSLHSQVPLYVVFTKMDLLYGFEAMYQSLDKAEREAVLGVTFSLNAADPDVWRTELKQFWQQWVAQLNGAMPDMMLNSVDAGQRSQLFSFTRQMQGLHDYVVQLLEGILYRGEHAQPLLRGVYLTSAQQRGQMDDIFTQSAAVQYHLAPQAFPTWPVSDTTPYFTKALFNQVLLAEPNLAGENGIWLQKTRKRM
Transmembrane helix 453-470 FIFSGVGALAALTLWGYW
Outside 471-1177 HYYHQLNYRAGEEVLTQAKTFLSIPPPEGDDRYGNLQLPLLNPIRDATLAYGNYHERSPFLADMGLYQGNNIGPYVESTYLQLLQQRFVPALMSGLLEQLNAAPKGSEEKLEILRVMRMLEDGSGRNAALVEQYMSHRWSQQFNGQRELQEQLSSHLNYALKHTDWHGARESGDQYAIKSFVPYLSPIQSAQQELSKLSIYQRVYQNLRIKAQDALPPALDLRDQIGASFDDIFVSGNDRLLVIPQFLTRSGLQSYFIKQNDQLVDLTVMDSWVLNLTKNVEYSEADRKEIHRQVTEQYLGDYTATWRAAMNNLSVSDFEGLPQAISAIEQVISGEQPFRRALQTLSDNTRLPVISDLIPAKEQQELLQKPDYLLLTRINREFSPETAVLVENGDKGSVIQSVYQKLTELHRYLLAIQNSPAPGKAALKAVQLRLDQNNSDPIFEVQQLAKNLPEPLNRWVGELAEQAWRVVMMEAIQSLEVEWNETVIKQYQTYLAGRYPFDPHAKQDVPLSEFERFFGPKGTLDAFYQQNLKPFVENNLTGGSDGELLIRPDVLQQLAQARKIRDTFFSAQNGLGTQFAIEPVLLSGNKRRSVLNLDGQLLDYAHGRSGVVHLVWPNSMRAGVESKLTLVPDESGKSPRTLSFSGPWAQLRLINAGELTNVGTNSFDVRFKVDGGEMTYRIFVDESDNPFAGGLFSKFSLPDTLY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8171 - -


  Protein sequence: 1178 a.a.    

>T6CP002536 NC_010465:434601-438134 [Yersinia pseudotuberculosis YPIII] [TssM]
MKLPFFIRIAKPAIPRLKASIPVVLALMACAALIWVWIYGPEWQLGENYPFETLLSRWLVTAVFVLVAVCWLSLKVMRRV
QHLEKLQLQTKIQLDDPVSADIEQQNHYLNGWKHQLQRHLNTPEYLYHLPWYMVIGARNSGKSTLIKEGYKLTEISASER
LHVEGAADLRVRCWLGEQAVIIDPAGVLIEQPTTPIAGKASLNSRLWQSLLSWLIEQRQRQPLNGIILTVDLHQMMTANK
AQRETYVADIHQRLQEIRLSLHSQVPLYVVFTKMDLLYGFEAMYQSLDKAEREAVLGVTFSLNAADPDVWRTELKQFWQQ
WVAQLNGAMPDMMLNSVDAGQRSQLFSFTRQMQGLHDYVVQLLEGILYRGEHAQPLLRGVYLTSAQQRGQMDDIFTQSAA
VQYHLAPQAFPTWPVSDTTPYFTKALFNQVLLAEPNLAGENGIWLQKTRKRMFIFSGVGALAALTLWGYWHYYHQLNYRA
GEEVLTQAKTFLSIPPPEGDDRYGNLQLPLLNPIRDATLAYGNYHERSPFLADMGLYQGNNIGPYVESTYLQLLQQRFVP
ALMSGLLEQLNAAPKGSEEKLEILRVMRMLEDGSGRNAALVEQYMSHRWSQQFNGQRELQEQLSSHLNYALKHTDWHGAR
ESGDQYAIKSFVPYLSPIQSAQQELSKLSIYQRVYQNLRIKAQDALPPALDLRDQIGASFDDIFVSGNDRLLVIPQFLTR
SGLQSYFIKQNDQLVDLTVMDSWVLNLTKNVEYSEADRKEIHRQVTEQYLGDYTATWRAAMNNLSVSDFEGLPQAISAIE
QVISGEQPFRRALQTLSDNTRLPVISDLIPAKEQQELLQKPDYLLLTRINREFSPETAVLVENGDKGSVIQSVYQKLTEL
HRYLLAIQNSPAPGKAALKAVQLRLDQNNSDPIFEVQQLAKNLPEPLNRWVGELAEQAWRVVMMEAIQSLEVEWNETVIK
QYQTYLAGRYPFDPHAKQDVPLSEFERFFGPKGTLDAFYQQNLKPFVENNLTGGSDGELLIRPDVLQQLAQARKIRDTFF
SAQNGLGTQFAIEPVLLSGNKRRSVLNLDGQLLDYAHGRSGVVHLVWPNSMRAGVESKLTLVPDESGKSPRTLSFSGPWA
QLRLINAGELTNVGTNSFDVRFKVDGGEMTYRIFVDESDNPFAGGLFSKFSLPDTLY*

  Nucleotide sequence: 3534 bp    

>T6CP002536 NC_010465:434601-438134 [Yersinia pseudotuberculosis YPIII] [TssM]
ATGAAATTGCCGTTCTTTATACGCATAGCCAAGCCCGCCATTCCTCGCCTTAAAGCGTCAATACCGGTGGTATTGGCGTT
GATGGCTTGTGCGGCACTCATTTGGGTATGGATTTACGGACCCGAGTGGCAATTGGGGGAAAATTACCCGTTTGAGACAT
TATTGAGCCGTTGGTTGGTCACGGCGGTATTTGTTTTGGTGGCCGTTTGTTGGCTCAGCCTGAAAGTCATGAGGCGAGTA
CAACACCTGGAAAAACTCCAACTGCAAACGAAAATTCAGCTCGACGACCCCGTCAGTGCTGATATCGAACAACAAAACCA
CTACCTCAATGGCTGGAAGCACCAACTTCAGCGCCATTTGAACACCCCGGAATATCTGTATCACCTGCCCTGGTACATGG
TCATTGGTGCGCGCAATAGCGGCAAAAGTACACTGATCAAAGAAGGGTATAAACTGACAGAGATCTCCGCATCCGAGCGG
CTCCATGTGGAAGGCGCAGCAGATCTGCGCGTCCGCTGCTGGTTGGGGGAACAAGCGGTTATTATCGATCCTGCGGGGGT
GCTGATTGAACAACCCACGACACCGATCGCGGGCAAAGCATCACTCAACAGCCGCTTATGGCAAAGTCTATTATCCTGGC
TGATTGAACAGCGCCAGCGTCAGCCGCTAAACGGCATTATTCTCACCGTCGATCTTCATCAGATGATGACCGCGAATAAA
GCGCAGCGGGAGACGTACGTCGCTGATATTCATCAACGGCTGCAAGAGATACGGCTGTCTTTGCACAGCCAGGTGCCGCT
GTATGTGGTGTTCACCAAAATGGACCTGCTGTACGGCTTCGAGGCCATGTACCAATCGCTGGATAAAGCCGAACGTGAAG
CGGTTCTGGGGGTGACGTTCAGCCTCAATGCGGCGGATCCGGACGTGTGGCGGACGGAGTTGAAACAGTTCTGGCAGCAA
TGGGTCGCACAACTGAATGGCGCGATGCCGGACATGATGCTGAACAGTGTGGATGCCGGGCAGCGTAGCCAGTTGTTTAG
CTTCACTCGTCAGATGCAGGGCCTGCACGATTACGTCGTGCAACTGCTGGAAGGCATTCTGTACCGTGGAGAACATGCCC
AGCCGCTGTTACGGGGGGTTTATCTCACGTCTGCCCAGCAACGCGGGCAAATGGACGATATCTTTACCCAATCTGCCGCG
GTGCAATATCACCTTGCGCCACAGGCCTTCCCGACCTGGCCGGTCTCGGATACGACGCCGTATTTTACCAAAGCGCTGTT
TAATCAGGTGCTGTTGGCCGAACCCAATCTGGCCGGAGAGAACGGTATCTGGCTGCAAAAAACGAGAAAGCGAATGTTCA
TTTTCTCGGGGGTGGGTGCCCTGGCCGCGCTGACCTTATGGGGCTACTGGCACTACTATCACCAGCTTAACTACCGGGCT
GGCGAAGAGGTATTAACCCAGGCAAAAACCTTCTTATCGATCCCACCGCCAGAAGGCGATGACCGTTATGGCAATCTGCA
ACTGCCGCTGCTAAACCCCATCCGTGACGCCACGCTGGCTTACGGTAATTACCATGAACGCAGCCCGTTCCTGGCGGATA
TGGGGTTATATCAGGGCAATAATATCGGGCCTTATGTCGAAAGCACTTACTTGCAACTCCTACAGCAACGTTTTGTCCCG
GCACTGATGAGCGGGCTGTTGGAACAACTGAACGCCGCACCGAAGGGCAGTGAAGAGAAACTGGAAATTCTGCGGGTGAT
GCGGATGTTGGAAGACGGCAGTGGCCGCAATGCCGCGCTGGTTGAACAATATATGAGCCACCGCTGGAGCCAACAATTCA
ACGGCCAGCGCGAGTTGCAGGAGCAACTGTCGAGCCACCTGAACTACGCACTGAAACACACCGACTGGCACGGCGCACGG
GAAAGTGGCGATCAATATGCGATCAAGAGCTTTGTCCCGTATCTCAGCCCGATCCAGTCAGCGCAGCAAGAGTTGAGTAA
ACTCTCGATCTACCAACGGGTGTATCAGAACCTGCGGATCAAAGCACAGGATGCGTTGCCGCCCGCGCTCGATTTGCGCG
ATCAGATCGGCGCAAGTTTTGACGACATCTTTGTCTCCGGTAACGATCGCCTGCTGGTGATCCCGCAATTCCTGACCCGT
AGCGGCTTACAGAGTTACTTCATCAAACAGAACGATCAACTGGTTGATCTCACGGTGATGGACAGTTGGGTACTTAATCT
CACCAAGAACGTCGAATACAGCGAGGCAGACCGCAAAGAGATCCATCGCCAGGTGACCGAACAGTATCTTGGCGATTATA
CCGCCACCTGGCGTGCGGCCATGAATAACCTGTCGGTCAGTGATTTTGAAGGCTTGCCACAGGCGATCAGCGCCATTGAA
CAGGTGATCAGCGGGGAACAACCTTTCCGCCGTGCACTGCAAACGCTGAGTGACAACACCCGCTTGCCGGTTATCTCGGA
TCTGATCCCCGCGAAGGAGCAGCAAGAGCTGCTGCAAAAACCCGATTACCTGCTGCTGACCCGCATCAACCGTGAGTTCT
CCCCCGAAACGGCGGTGCTGGTGGAGAATGGCGATAAAGGCAGCGTGATCCAAAGTGTTTACCAAAAACTGACCGAGCTA
CACCGCTATCTGTTGGCGATCCAAAACTCGCCCGCGCCGGGCAAAGCGGCGTTGAAGGCGGTGCAATTACGTCTGGATCA
AAACAACAGTGATCCGATTTTCGAAGTCCAGCAACTGGCTAAAAACCTGCCGGAGCCGCTAAACCGCTGGGTGGGCGAAC
TGGCAGAGCAAGCCTGGCGGGTGGTGATGATGGAGGCTATCCAGTCACTGGAAGTGGAGTGGAATGAGACGGTGATCAAA
CAGTATCAAACCTACCTGGCCGGACGTTATCCCTTCGATCCTCACGCGAAACAGGATGTACCACTCAGTGAGTTTGAACG
CTTCTTCGGGCCGAAAGGCACGCTCGATGCATTCTATCAGCAGAACCTGAAACCGTTTGTCGAAAACAACCTGACCGGTG
GCAGCGATGGCGAATTGCTGATCCGGCCTGATGTGCTACAGCAACTGGCGCAGGCGCGGAAAATTCGCGACACCTTCTTC
TCGGCCCAAAACGGCCTGGGCACACAGTTTGCGATTGAACCGGTGCTGTTAAGTGGCAACAAGCGCCGCAGCGTATTGAA
TTTGGATGGGCAATTACTGGATTACGCCCATGGTCGCAGCGGCGTAGTGCATCTGGTTTGGCCAAACTCGATGCGTGCAG
GAGTGGAAAGCAAACTGACGTTAGTCCCGGATGAGAGCGGCAAATCACCGCGCACCCTCAGCTTCAGCGGCCCTTGGGCG
CAATTGCGGCTGATCAACGCCGGTGAACTGACCAATGTGGGCACCAACTCCTTCGATGTCCGCTTCAAGGTTGATGGCGG
CGAGATGACGTACCGCATCTTTGTTGATGAATCCGACAACCCATTCGCGGGCGGTTTGTTCAGTAAATTCAGTCTGCCAG
ACACTCTGTATTGA