SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP002090
Component protein type	TssC
T6SS ID (Type)	T6SS00208 (Type i1)
Strain	Vibrio cholerae O395
Replicon	chromosome I
Sequence	Protein sequence (492 a.a.); Nucleotide sequence (1476 bp)
Reference	[1] Bernard CS, Brunet YR, Gavioli M, et al. Regulation of type VI secretion gene clusters by sigma54 and cognate enhancer binding proteins. J Bacteriol. 2011 May;193(9):2158-67. doi: 10.1128/JB.00029-11. Epub 2011 Mar 4. PMID: 21378190

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	VC0395_RS00155
Coordinate (Strand)	33816..35291 (-)
NCBI ID	WP_000108140.1
RefSeq	NC_009456
Uniprot ID	A0A085SGI6_VIBCL
KEGG ID	vcq:EN18_04265
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
VipB	PF05943.14	8.6e-127	65..364
VipB_2	PF18945.2	1.8e-45	377..488

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 492 a.a.

						>T6CP002090 NC_009456:c35291-33816 [Vibrio cholerae O395] [TssC]
MSTTEKVLERPQLAQGSLLDEIMAQTRIAPSEEGYDIAKKGVAAFIENLMGSQHSAEPVNKSLVDQMLVELDKKISAQMD
EILHNSQFQAMESAWRGLKLFVDRTDFRENNKVEILHVTKDELLEDFEFAPETAQSGLYKHVYSAGYGQFGGEPVGAIIG
NYAFTPSTPDMKLLQYMGALGAMAHAPFISSVGPEFFGIDSFEELPNIKDLKSTFESPKYTKWRSLRESEDARYLGLTAP
RFLLRVPYDPIENPVKSFNYAENVSASHEHYLWGNTAFAFATRLTDSFAKYRWCPNIIGPQSGGAVEDLPVHVFESMGAL
QSKIPTEVLITDRKEFELAEEGFIALTMRKGSDNAAFFSANSIQKPKVFPNTKEGKEAETNYKLGTQLPYMMIINRLAHY
VKVLQREQIGAWKERQDLERELNSWIKQYVADQENPPADVRSRRPLRAARIEVMDVEGNPGWYQVSLSVRPHFKYMGANF
ELSLVGRLDQA*					

Nucleotide sequence: 1476 bp

						>T6CP002090 NC_009456:c35291-33816 [Vibrio cholerae O395] [TssC]
ATGTCTACGACTGAAAAGGTATTGGAAAGGCCACAGCTTGCTCAAGGCAGCCTTCTTGATGAAATTATGGCGCAAACCCG
TATCGCACCAAGCGAAGAGGGTTACGACATCGCGAAAAAAGGTGTTGCAGCGTTTATCGAAAATCTTATGGGTTCACAAC
ACTCTGCTGAGCCTGTCAACAAATCTCTGGTTGACCAAATGTTGGTTGAACTGGATAAGAAAATCAGTGCACAGATGGAT
GAAATCCTGCACAACTCGCAATTTCAAGCGATGGAATCGGCGTGGCGCGGTTTGAAGCTGTTCGTGGATCGCACTGATTT
TCGTGAAAATAACAAAGTCGAAATCCTTCACGTAACCAAAGATGAACTGCTGGAAGATTTCGAGTTTGCTCCAGAAACGG
CTCAGTCCGGTCTTTACAAGCACGTTTATTCTGCCGGTTATGGTCAATTTGGTGGCGAACCTGTTGGCGCGATCATTGGT
AACTATGCGTTTACCCCTTCAACGCCAGATATGAAGCTGCTGCAATACATGGGCGCACTGGGTGCCATGGCGCATGCTCC
TTTCATTTCAAGCGTAGGTCCTGAATTCTTTGGTATCGATTCTTTTGAAGAACTGCCTAACATTAAAGATCTCAAGTCGA
CATTTGAAAGCCCGAAATACACCAAATGGCGTTCATTGCGTGAATCGGAAGATGCGCGCTATCTTGGTTTGACTGCGCCT
CGTTTCCTGCTGCGTGTTCCTTACGATCCAATCGAAAATCCAGTGAAGTCGTTCAATTATGCGGAAAACGTCAGTGCTTC
GCACGAGCACTACCTGTGGGGTAACACGGCATTTGCCTTCGCAACTCGTTTGACGGATAGCTTTGCTAAATATCGCTGGT
GTCCAAACATTATCGGTCCACAAAGTGGTGGTGCAGTTGAAGATCTGCCGGTGCATGTCTTTGAATCTATGGGTGCATTG
CAAAGCAAGATCCCAACCGAAGTCCTGATCACGGACCGTAAAGAGTTTGAACTGGCGGAAGAAGGTTTTATTGCTCTTAC
TATGCGTAAAGGCAGTGATAACGCGGCGTTCTTCTCTGCAAACTCCATTCAAAAACCTAAGGTTTTCCCAAATACCAAAG
AAGGCAAAGAAGCGGAAACCAACTACAAGTTGGGTACCCAGTTGCCGTACATGATGATCATCAACCGTTTGGCGCACTAT
GTGAAAGTTCTGCAACGTGAGCAGATCGGTGCTTGGAAAGAGCGTCAAGATCTTGAGCGTGAACTGAACTCATGGATCAA
ACAATACGTTGCTGATCAAGAGAACCCACCTGCAGACGTACGTAGCCGTCGTCCACTTCGTGCTGCGCGCATTGAAGTGA
TGGATGTGGAAGGCAATCCAGGTTGGTATCAGGTGTCGCTCTCGGTTCGTCCTCACTTTAAGTACATGGGTGCGAACTTT
GAGTTGTCATTAGTTGGACGTCTTGATCAAGCCTGA					