SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP001522
Component protein type	TssC
T6SS ID (Type)	T6SS00155 (Type i1)
Strain	Escherichia coli APEC O1
Replicon	chromosome
Sequence	Protein sequence (495 a.a.); Nucleotide sequence (1485 bp)
Reference	[1] Boyer F, Fichant G, Berthod J, et al. Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? BMC Genomics. 2009 Mar 12;10:104. doi: 10.1186/1471-2164-10-104. PMID: 19284603

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	APECO1_RS01210
Coordinate (Strand)	261002..262486 (-)
NCBI ID	WP_000111582.1
RefSeq	NC_008563
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
VipB	PF05943.14	4.3e-119	68..367
VipB_2	PF18945.2	1.4e-44	381..491

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 495 a.a.

						>T6CP001522 NC_008563:c262486-261002 [Escherichia coli APEC O1] [TssC]
MSVKEEIAPVSASQTAAPPSLLDEIMAQTRVQPKSESYDITRQGVSAFIAAMLQGDSSAEPINILAVDAMIADIDARTSR
QMDAIIHAPEFQELESLLRSLKLLVERADTRENIKVHFLNVTQEELLDDFEFAPEITQSAYYKHVYSSGYGQFGGEPVAA
VIGNFAFKNTTPDMKLLKYISQVSAMAHSPFLSSVSSEFFGLDSWTELPGIKEPGAIFEGPAYSRWRALRESEDSRYLGL
TAPRFLLRHPYSPDENPVKTFRYHEDVSQSHESYLWGNTSFLLAANLAESFAKYRWCPNIIGPSSGGAVKDLPVHLYESM
GQMQAKIPTEVLITDRREYELAEEGFITLTMRKGSDNACFFSANSVQKPKTFPKTPEGKAAETNYKLGTQLPYLFVISRL
AHYIKVIQREQLGSWKERSDLERELNTWIRQYVADQENPPAEVRSHRPLRQAKIEVLDVDGEPGWYQVAISVRPHFKYMG
ASFDLSLVGRLDKE*					

Nucleotide sequence: 1485 bp

						>T6CP001522 NC_008563:c262486-261002 [Escherichia coli APEC O1] [TssC]
ATGTCAGTAAAGGAAGAAATTGCTCCCGTCAGCGCGTCTCAAACCGCCGCGCCCCCATCTCTGCTTGATGAAATCATGGC
GCAAACCCGCGTCCAGCCTAAATCAGAAAGCTACGATATCACCCGCCAGGGCGTGAGCGCCTTTATTGCCGCCATGTTAC
AGGGCGACAGTAGCGCTGAACCTATCAATATCCTGGCCGTTGACGCCATGATTGCTGATATTGATGCCCGAACCAGCAGG
CAGATGGATGCCATTATTCATGCCCCGGAGTTTCAGGAACTGGAATCCCTGCTGCGCTCGCTGAAGCTGCTGGTTGAACG
CGCGGATACACGGGAAAACATCAAAGTCCATTTCCTGAATGTCACTCAGGAAGAACTGCTGGATGATTTCGAATTTGCAC
CTGAAATCACGCAGTCTGCGTATTACAAGCATGTATATTCAAGCGGTTACGGACAATTTGGCGGTGAGCCAGTGGCGGCG
GTAATCGGCAACTTTGCCTTTAAGAACACCACGCCGGATATGAAGCTGCTGAAATATATCAGCCAGGTCAGCGCGATGGC
GCACAGCCCGTTCCTGTCGTCAGTATCATCCGAATTTTTCGGTCTGGATTCATGGACAGAGTTACCGGGGATCAAAGAAC
CGGGTGCCATCTTTGAAGGCCCGGCCTACTCCCGCTGGCGCGCCCTGCGTGAATCGGAAGATTCCCGTTACCTGGGCCTG
ACCGCCCCCCGGTTCCTGCTGCGCCACCCTTACTCACCGGATGAAAACCCTGTCAAAACCTTCCGTTACCATGAAGATGT
CAGCCAGAGTCATGAGTCTTATCTGTGGGGGAATACCTCGTTTTTACTGGCCGCCAACCTGGCGGAAAGTTTTGCTAAGT
ATCGCTGGTGCCCAAATATTATTGGCCCTTCCAGCGGCGGCGCAGTCAAAGACCTCCCGGTGCATCTGTATGAATCCATG
GGGCAAATGCAGGCAAAAATTCCGACTGAAGTGTTGATCACTGACCGGAGAGAGTATGAGCTGGCGGAAGAGGGCTTTAT
CACACTGACCATGCGTAAAGGGTCTGATAATGCGTGCTTTTTCTCGGCCAACTCGGTGCAGAAACCCAAAACATTCCCCA
AAACCCCCGAAGGCAAGGCTGCGGAGACCAACTATAAACTCGGCACCCAGCTGCCATACTTGTTTGTTATCAGCAGGTTA
GCGCATTACATCAAGGTAATTCAGCGCGAACAGCTTGGCTCATGGAAAGAACGTAGTGACCTGGAGCGTGAGCTGAACAC
CTGGATTCGCCAGTATGTTGCTGACCAGGAAAATCCGCCTGCCGAAGTCCGCAGCCACCGGCCTTTGCGTCAGGCTAAGA
TCGAGGTACTGGATGTGGATGGTGAGCCGGGCTGGTACCAGGTCGCGATTTCTGTCAGACCGCATTTTAAATACATGGGT
GCCAGTTTCGACCTGAGCCTGGTCGGACGACTGGATAAGGAATAA					