SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP000623
Component protein type	TssK
T6SS ID (Type)	T6SS00077 (Type i4b)
Strain	Burkholderia pseudomallei K96243
Replicon	chromosome I
Sequence	Protein sequence (449 a.a.); Nucleotide sequence (1347 bp)
Reference	[1] Burtnick MN, Brett PJ, Harding SV, et al. The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 2011 Apr;79(4):1512-25. doi: 10.1128/IAI.01218-10. Epub 2011 Feb 7. PMID: 21300775

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	BPS_RS16755
Coordinate (Strand)	3715048..3716394 (+)
NCBI ID	WP_004521949.1
RefSeq	NC_006350
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_VasE	PF05936.14	3.9e-140	19..446

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 449 a.a.

						>T6CP000623 NC_006350:3715048-3716394 [Burkholderia pseudomallei K96243] [TssK]
MSYSAKVLWGEGLFLRPQHFQRQDAYHEARLFESIQAIQPYNWGVRSVRFDRDALGSNVLRASELSLVFPDGALYSAPQA
DELPPPIALDTLPEGINEFTFYLALHPLRETGSNYADDRDAGFVSRFVSEQASVADHFTDAAEADITFLKTNVKLIAHSE
PRDQLLSIPLVRVRRTATSGFEIDDGFVPPCLAIEASPILHQRLRQLIDALQAKVNALYGFHREPTKNIIEFRSGDIASF
WLLHTASAAFAALAHLHQHSALHPERLFQELLRLAGQLMTFSKGYVLADLPAYRHDDPGPGFARLDSILRELLETVISTR
YFAITLEEVRPSFHVGRLDSGKIDDKTAFYLAVSADMPSVELVDAVPARFKVGAPDDVDKLVLSAMPGVRLAYTPQVPPA
IPVRPGACYFALDARSPLYERMLQAQSAMIYAPSGINDLKFELIAVTS*					

Nucleotide sequence: 1347 bp

						>T6CP000623 NC_006350:3715048-3716394 [Burkholderia pseudomallei K96243] [TssK]
ATGAGTTATTCGGCCAAGGTGCTCTGGGGAGAAGGCCTCTTTCTGAGGCCGCAGCACTTTCAGCGGCAGGACGCGTATCA
CGAAGCGCGCCTGTTCGAATCGATCCAGGCGATCCAGCCGTACAACTGGGGCGTGCGTTCGGTGCGGTTCGATCGCGACG
CGCTCGGCAGCAACGTGCTGCGCGCGAGCGAACTGTCGCTCGTGTTTCCGGACGGCGCGCTCTACTCCGCGCCGCAAGCC
GACGAACTGCCGCCGCCCATCGCGCTCGACACGCTGCCCGAAGGCATCAACGAATTCACGTTCTACCTCGCGCTGCACCC
GCTGCGCGAGACCGGCTCGAACTACGCGGACGACCGCGACGCCGGCTTCGTGTCGCGCTTCGTCAGCGAACAGGCGAGCG
TTGCCGATCACTTCACCGACGCCGCGGAAGCGGACATCACGTTCCTGAAGACGAACGTGAAGCTGATCGCGCACAGCGAG
CCGCGCGACCAGTTGCTGTCGATCCCGCTCGTACGCGTGCGCCGCACCGCGACGTCCGGCTTCGAGATCGACGACGGCTT
CGTGCCGCCGTGCCTCGCGATCGAGGCGTCGCCGATCCTGCACCAGCGCCTGCGCCAGTTGATCGACGCGCTGCAGGCGA
AGGTGAATGCACTGTACGGTTTCCATCGCGAGCCGACGAAGAACATCATCGAGTTCCGCTCGGGCGACATCGCATCGTTC
TGGCTGCTGCACACGGCGAGCGCCGCGTTCGCCGCGCTCGCGCACCTGCACCAGCATTCGGCCTTGCATCCGGAGCGGCT
GTTCCAGGAACTACTGCGCCTCGCGGGCCAGTTGATGACGTTCTCGAAGGGCTACGTGCTCGCCGATCTGCCCGCGTACC
GGCATGACGATCCGGGCCCGGGCTTCGCGCGGCTCGATTCGATCCTGCGCGAGCTGCTCGAGACCGTGATCTCGACGCGC
TACTTCGCGATCACGCTCGAGGAAGTGCGGCCGTCGTTCCATGTCGGGCGGCTCGACTCGGGCAAGATCGACGACAAGAC
CGCGTTCTATCTCGCGGTGTCGGCCGACATGCCGTCGGTCGAACTCGTCGATGCGGTGCCCGCGCGCTTCAAGGTGGGCG
CGCCGGACGACGTCGACAAGCTCGTGCTCTCCGCGATGCCGGGCGTGCGCCTCGCGTACACGCCGCAGGTGCCGCCCGCG
ATTCCCGTGCGCCCGGGCGCATGCTATTTCGCACTCGATGCGCGCAGCCCGCTCTATGAGCGGATGCTGCAGGCCCAGTC
GGCGATGATCTATGCGCCGTCCGGAATCAACGATCTCAAATTCGAACTGATCGCCGTCACGTCATGA					