SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP000620
Component protein type	TssC
T6SS ID (Type)	T6SS00077 (Type i4b)
Strain	Burkholderia pseudomallei K96243
Replicon	chromosome I
Sequence	Protein sequence (497 a.a.); Nucleotide sequence (1491 bp)
Reference	[1] Burtnick MN, Brett PJ, Harding SV, et al. The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 2011 Apr;79(4):1512-25. doi: 10.1128/IAI.01218-10. Epub 2011 Feb 7. PMID: 21300775

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	BPS_RS16735
Coordinate (Strand)	3711217..3712707 (-)
NCBI ID	WP_004521953.1
RefSeq	NC_006350
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
VipB	PF05943.14	1.6e-134	68..370
VipB_2	PF18945.2	1e-46	380..490

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 497 a.a.

						>T6CP000620 NC_006350:c3712707-3711217 [Burkholderia pseudomallei K96243] [TssC]
MNQQTAAAQSTGVQAGTESSLLDEIVEKSKVAKSESEHARAKDLIGELVSQVLDGTVVVSDNLSATIDARVAELDRLISS
QLSAVMHAAEFQRLESTWRGLDYLVKESNTGSTIKIKALHAPKRDLVRDFKNATEFDQSALFKKVYEEEFGTFGGSPFGV
LVGDYEISRQPEDQYFIEQMSHVAAAAHAPFIASAAPELLGLESFADLGKPRDLGKVFDTVEYAKWKSFRDSEDSRYVGL
TLPRFLGRLPFNPKDGAIAESFNFVEDVDGTDHDKYLWCNASWAFAARLTAAFDDFGWCAAIRGVEGGGLVEDLPTHTFK
TDDGEIALKCPTEIAITDRREKELSDLGFIPLVHCKNSDYAAFFAAQSVQKPKKYSTDSANANAVLSAQLQYIFSVSRIA
HYLKAMMRDKIGSFASAQNVETFLNRWISQYVLLDDDATQEQKAQFPLREASVQVSEIPGKPGAYRSVAFLRPHFQLDEL
SISLRLVADLPKPANS*					

Nucleotide sequence: 1491 bp

						>T6CP000620 NC_006350:c3712707-3711217 [Burkholderia pseudomallei K96243] [TssC]
ATGAACCAGCAAACGGCTGCGGCCCAATCCACCGGCGTTCAAGCCGGCACGGAATCCTCGCTGCTCGACGAGATCGTCGA
GAAGAGCAAGGTCGCGAAATCCGAATCCGAGCATGCGCGCGCGAAGGATCTGATCGGCGAGCTCGTCAGTCAGGTGCTTG
ACGGCACGGTGGTGGTGTCGGACAACCTGTCGGCGACCATCGACGCGCGCGTCGCGGAGCTCGATCGCCTGATCTCGTCG
CAGCTCTCGGCCGTGATGCACGCGGCGGAGTTCCAGCGTCTCGAGAGCACCTGGCGCGGGCTCGATTACCTGGTGAAGGA
AAGCAACACCGGCTCGACGATCAAGATCAAGGCGCTGCACGCGCCGAAGCGCGATCTCGTGCGCGATTTCAAGAACGCGA
CCGAGTTCGATCAGAGCGCGCTCTTCAAGAAGGTGTACGAAGAGGAATTCGGCACGTTCGGCGGCTCGCCGTTCGGCGTG
CTGGTGGGCGACTACGAGATCTCGCGCCAGCCGGAAGACCAGTACTTCATCGAGCAGATGTCGCACGTCGCGGCCGCCGC
GCACGCGCCGTTCATCGCGTCGGCGGCGCCCGAGCTGCTCGGGCTCGAATCGTTCGCGGATCTCGGCAAGCCGCGCGATC
TCGGCAAGGTGTTCGATACCGTTGAATACGCGAAGTGGAAGTCGTTCCGCGATTCCGAGGATTCGCGCTACGTCGGCCTC
ACGCTGCCGCGCTTTCTCGGCCGCCTGCCGTTCAATCCGAAGGACGGCGCGATCGCGGAGAGCTTCAACTTCGTCGAGGA
CGTCGACGGCACCGATCACGACAAGTACCTGTGGTGCAACGCGTCGTGGGCGTTCGCCGCGCGCCTGACGGCGGCGTTCG
ACGACTTCGGCTGGTGCGCGGCGATTCGCGGCGTCGAAGGCGGCGGCCTCGTCGAGGATCTGCCGACCCACACGTTCAAG
ACCGACGACGGCGAAATCGCGCTCAAGTGCCCGACCGAGATCGCGATCACCGACCGCCGCGAGAAGGAACTGAGCGATCT
CGGTTTCATCCCGCTCGTGCACTGCAAGAATTCCGATTACGCCGCGTTCTTTGCCGCGCAGTCGGTGCAGAAACCCAAGA
AATACAGCACCGACAGCGCCAACGCGAACGCCGTCCTGTCCGCTCAGCTGCAGTACATCTTCTCGGTATCGCGCATCGCG
CATTACCTGAAGGCGATGATGCGCGACAAGATCGGCAGCTTCGCGTCCGCGCAGAACGTCGAAACGTTCCTCAATCGCTG
GATCTCGCAGTACGTGTTGCTCGACGACGACGCGACGCAGGAACAGAAGGCGCAGTTCCCGCTGCGCGAGGCCTCCGTAC
AAGTGTCAGAGATTCCGGGCAAGCCGGGTGCGTATCGTTCGGTCGCGTTTTTGCGTCCGCACTTCCAGCTCGACGAGTTG
TCGATTTCTCTGCGCCTTGTCGCTGATCTGCCCAAACCGGCAAATTCATAA					