SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP000587
Component protein type	TssA
T6SS ID (Type)	T6SS00068 (Type i3)
Strain	Burkholderia mallei ATCC 23344
Replicon	chromosome II
Sequence	Protein sequence (360 a.a.); Nucleotide sequence (1080 bp)
Reference	[1] Schell MA, Ulrich RL, Ribot WJ, et al. Type VI secretion is a major virulence determinant in Burkholderia mallei. Mol Microbiol. 2007 Jun;64(6):1466-85. PMID: 17555434

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	BMA_RS18010
Coordinate (Strand)	394463..395542 (+)
NCBI ID	WP_004190988.1
RefSeq	NC_006349
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
ImpA_N	PF06812.14	2.1e-35	12..134

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-359	MQSSDPIESLLAGVAPDAPCGANLEYEQDFLRLQESATPRPEQQYGDTVIPAEAPDWSAVERLALELTARTKDLRVAAHLARSWTELRGMPGYADGLRLVAGMLDRWWDDVHPRLDADGDHDPAPRANALAEIAGAHDCARAARRQALFDGGPSVRDAERVFDGRDGGEHGYPGGRERLIADLVRARDGGQPTLQAAFAALDALDAIRARVASALGGEWVPDASDFEKALRRIVRDGLPPPAAAPAATNGAANVANAAHGGAANGVTNSAANGAASGGAPAFAANGRAWRDAELTSRDDVQLGLEKMCRYFELHEPSHPAPILLRRAQRLLSLDFYEIIRDLAPESLPKLDLLSGQRNE

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9757	-	-

Protein sequence: 360 a.a.

						>T6CP000587 NC_006349:394463-395542 [Burkholderia mallei ATCC 23344] [TssA]
MQSSDPIESLLAGVAPDAPCGANLEYEQDFLRLQESATPRPEQQYGDTVIPAEAPDWSAVERLALELTARTKDLRVAAHL
ARSWTELRGMPGYADGLRLVAGMLDRWWDDVHPRLDADGDHDPAPRANALAEIAGAHDCARAARRQALFDGGPSVRDAER
VFDGRDGGEHGYPGGRERLIADLVRARDGGQPTLQAAFAALDALDAIRARVASALGGEWVPDASDFEKALRRIVRDGLPP
PAAAPAATNGAANVANAAHGGAANGVTNSAANGAASGGAPAFAANGRAWRDAELTSRDDVQLGLEKMCRYFELHEPSHPA
PILLRRAQRLLSLDFYEIIRDLAPESLPKLDLLSGQRNE*					

Nucleotide sequence: 1080 bp

						>T6CP000587 NC_006349:394463-395542 [Burkholderia mallei ATCC 23344] [TssA]
ATGCAGAGTTCAGACCCGATCGAATCGTTGCTCGCCGGCGTCGCGCCCGACGCGCCGTGCGGCGCGAATCTCGAATACGA
GCAGGATTTCCTGCGGCTGCAGGAGAGCGCGACGCCGCGGCCCGAACAGCAGTACGGCGACACCGTGATCCCGGCCGAAG
CGCCGGACTGGAGCGCGGTCGAGCGTCTCGCGCTCGAGCTGACGGCGCGCACGAAGGATCTGCGCGTGGCCGCGCATCTC
GCGCGCAGTTGGACCGAACTGCGCGGCATGCCCGGCTACGCGGATGGGCTGAGGCTCGTCGCGGGGATGCTGGACCGGTG
GTGGGACGACGTGCACCCGCGCCTGGACGCCGACGGCGACCACGACCCGGCCCCGCGCGCGAACGCGCTGGCGGAAATCG
CGGGCGCGCACGACTGCGCGCGCGCCGCGCGCCGACAGGCGCTCTTCGATGGCGGCCCGAGCGTGCGCGATGCCGAGCGC
GTGTTCGATGGCCGCGACGGCGGCGAGCACGGCTACCCGGGCGGCCGCGAGCGGCTGATCGCCGATCTGGTTCGCGCGCG
CGACGGCGGGCAGCCGACGCTGCAGGCGGCGTTCGCCGCGCTCGACGCGCTCGATGCGATTCGCGCGCGCGTCGCATCGG
CGCTCGGCGGCGAATGGGTGCCCGACGCGAGCGACTTCGAGAAGGCGCTGCGCCGGATCGTGCGCGACGGGTTGCCGCCG
CCCGCGGCCGCGCCCGCCGCGACAAACGGCGCGGCGAATGTGGCGAATGCGGCGCACGGCGGCGCGGCAAACGGCGTCAC
GAACAGTGCCGCGAACGGCGCGGCTTCGGGCGGCGCGCCGGCTTTCGCCGCGAACGGCCGCGCGTGGCGCGACGCGGAGC
TGACGAGCCGCGACGACGTTCAGCTCGGCCTCGAAAAAATGTGCCGCTACTTCGAGCTGCACGAGCCGAGCCATCCGGCG
CCGATCCTGCTGCGCCGCGCGCAGCGGCTGCTGTCGCTCGACTTCTACGAAATCATCCGGGATCTCGCGCCGGAGAGCCT
GCCGAAGCTCGACTTGCTGAGCGGCCAGCGCAACGAATGA					