Detailed information of component protein


Summary

Component ID T6CP000586
Component protein type TssM
T6SS ID (Type) T6SS00068 insolico (Type i3)
Strain Burkholderia mallei ATCC 23344
Replicon chromosome II
Sequence Protein sequence (1210 a.a.); Nucleotide sequence (3630 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) BMA_RS17990
Coordinate (Strand) 387061..390690 (+)
NCBI ID WP_004190681.1
RefSeq NC_006349
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related_N PF14331.8 1.7e-90 217..475
IcmF-related PF06761.14 7.2e-89 527..835
IcmF_C PF06744.14 3.1e-26 1086..1190
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-16 MSHAVARIVRPLPSRD
Transmembrane helix 17-39 IWTFAGLVVLACFVWLAGPLFAF
Outside 40-48 AEFRPFESG
Transmembrane helix 49-68 AVRAATIVALFVAWGARIAW
Inside 69-466 RGWRAGQLNAQLLNQLREAAPRPAATGDPAQAQLDELRSRFDEAATLLKKVRFGEADGARKGLPRWLEQMSRQYLYQLPWYVFIGAPGSGKTTALVNSGLSFPLAEQFGRAAIRGVGGTRHCDWWFTNDAVLIDTAGRYTTHESNRALDEAEWKGFVDLLKKYRARQPLNGAMLTISVADLLGASEAERTQHAMVLRKRLLELRAQLGIRFPVYLLVTKADLLAGFAEYFGGFGRAECAQVWGFTFPLAESEAPGFELRAAFDREYRLLHQRLNDGLPELLASQTDARQREMTYLLPQQIADLQDMLGQFVAEVFSVSSFEPMPMLRGVYLTSGTQEGTAFDRVMSGIKRFLKIEGVPPAAQTGSSGRSFFLKSLLQDHIFREAALAGSNLRWHQRQR
Transmembrane helix 467-489 VLQIVGYAAIALLCVAVLFAWLR
Outside 490-1209 SYSRNRDYLDEVAARVPAVDAQIGRAKFTGAADIVQLLPVLDELSGLPNAGGVDLRHPPLAYRWGLFQGEKIEEASDAVYRRALDDVLLPIAASRMEQALRDARPDEVEYAYAALKAYLMLYDSAHYDPAFVQAVVDLEMERALPADFSSAQRSALRAHLGALFGNRVAVSPFPMNERLVADVRERLRQVPFSQRLYRQLARTLHASTASYDFSVARAVGPDASLVFRRQSGKSLADGVPGLYTRSGYRNVFAPRLPGAIDSYGREEVWVLNLGASEIPNPADAAAWARDIRQLYLNDYIKTWDDYLADIRLQRTSTLAQSIQVARTLSSADSPLTRLMVALARDTPLGDAPGGARNLASRAQDKVDEARNSLAQIFAGQPGGEAGAAAAPPASPEQIVDSHFAGLRAFAPGGGDQAASFDAVLKAIDALYTYLTATDDALRSGAAPPPSDAPARLRAQAGRLPTPVREVLDDLSNVANGSIASVEQRNVAQRAGANVGDFCRQAIAGRYPFARGAARDVAPSDFAQLFAAGGLMDDFFQKNLQTLVDTTAHPWRFNNRNAEADPSAAAMLGSFEKAAVIRDVYFGGGARTAQIKVEIVPLEMDPSISEMLLDVDGQIVRYAHGPQVPTAVQWPGTRGSNQVRLQVTEQSGATGGFTTEGPWALHRLFDRAGVSGGRGPEQMVARFAVDGKPIVLQVTASSVRNPFRLPQMESFTCPPKQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9653 - -


  Protein sequence: 1210 a.a.    

>T6CP000586 NC_006349:387061-390690 [Burkholderia mallei ATCC 23344] [TssM]
MSHAVARIVRPLPSRDIWTFAGLVVLACFVWLAGPLFAFAEFRPFESGAVRAATIVALFVAWGARIAWRGWRAGQLNAQL
LNQLREAAPRPAATGDPAQAQLDELRSRFDEAATLLKKVRFGEADGARKGLPRWLEQMSRQYLYQLPWYVFIGAPGSGKT
TALVNSGLSFPLAEQFGRAAIRGVGGTRHCDWWFTNDAVLIDTAGRYTTHESNRALDEAEWKGFVDLLKKYRARQPLNGA
MLTISVADLLGASEAERTQHAMVLRKRLLELRAQLGIRFPVYLLVTKADLLAGFAEYFGGFGRAECAQVWGFTFPLAESE
APGFELRAAFDREYRLLHQRLNDGLPELLASQTDARQREMTYLLPQQIADLQDMLGQFVAEVFSVSSFEPMPMLRGVYLT
SGTQEGTAFDRVMSGIKRFLKIEGVPPAAQTGSSGRSFFLKSLLQDHIFREAALAGSNLRWHQRQRVLQIVGYAAIALLC
VAVLFAWLRSYSRNRDYLDEVAARVPAVDAQIGRAKFTGAADIVQLLPVLDELSGLPNAGGVDLRHPPLAYRWGLFQGEK
IEEASDAVYRRALDDVLLPIAASRMEQALRDARPDEVEYAYAALKAYLMLYDSAHYDPAFVQAVVDLEMERALPADFSSA
QRSALRAHLGALFGNRVAVSPFPMNERLVADVRERLRQVPFSQRLYRQLARTLHASTASYDFSVARAVGPDASLVFRRQS
GKSLADGVPGLYTRSGYRNVFAPRLPGAIDSYGREEVWVLNLGASEIPNPADAAAWARDIRQLYLNDYIKTWDDYLADIR
LQRTSTLAQSIQVARTLSSADSPLTRLMVALARDTPLGDAPGGARNLASRAQDKVDEARNSLAQIFAGQPGGEAGAAAAP
PASPEQIVDSHFAGLRAFAPGGGDQAASFDAVLKAIDALYTYLTATDDALRSGAAPPPSDAPARLRAQAGRLPTPVREVL
DDLSNVANGSIASVEQRNVAQRAGANVGDFCRQAIAGRYPFARGAARDVAPSDFAQLFAAGGLMDDFFQKNLQTLVDTTA
HPWRFNNRNAEADPSAAAMLGSFEKAAVIRDVYFGGGARTAQIKVEIVPLEMDPSISEMLLDVDGQIVRYAHGPQVPTAV
QWPGTRGSNQVRLQVTEQSGATGGFTTEGPWALHRLFDRAGVSGGRGPEQMVARFAVDGKPIVLQVTASSVRNPFRLPQM
ESFTCPPKQ*

  Nucleotide sequence: 3630 bp    

>T6CP000586 NC_006349:387061-390690 [Burkholderia mallei ATCC 23344] [TssM]
ATGAGCCACGCTGTCGCACGCATCGTTCGCCCGCTGCCGTCGCGGGACATCTGGACGTTCGCCGGCCTCGTCGTGCTGGC
GTGTTTCGTTTGGCTTGCCGGGCCGCTGTTCGCGTTCGCCGAGTTCCGCCCGTTCGAGAGCGGCGCGGTGCGCGCGGCGA
CGATCGTCGCGCTGTTCGTCGCGTGGGGCGCGCGGATCGCGTGGCGCGGCTGGCGCGCGGGGCAACTGAACGCGCAGTTG
CTCAACCAGTTGCGCGAAGCGGCGCCGCGGCCCGCCGCGACGGGCGATCCCGCGCAGGCGCAGCTCGACGAGCTGCGCAG
CCGCTTCGACGAAGCCGCGACGCTGTTGAAGAAAGTCCGTTTCGGCGAAGCCGACGGCGCGCGCAAGGGCCTGCCGCGGT
GGCTCGAGCAGATGTCGCGCCAGTATCTGTACCAACTGCCGTGGTACGTGTTCATCGGCGCGCCGGGCTCGGGCAAGACG
ACGGCGCTCGTCAACTCGGGGCTGAGCTTTCCGCTCGCCGAGCAGTTCGGGCGCGCGGCGATTCGCGGCGTCGGCGGCAC
GCGGCACTGCGACTGGTGGTTCACGAACGACGCGGTGCTGATCGACACCGCGGGCCGCTACACGACGCACGAGAGCAACC
GCGCGCTCGACGAGGCCGAATGGAAGGGCTTCGTCGATCTGCTGAAGAAGTACCGCGCGCGCCAGCCGCTGAACGGCGCG
ATGCTGACGATCAGCGTCGCCGATCTGCTCGGCGCGTCGGAGGCGGAGCGCACGCAGCACGCGATGGTGCTGCGCAAGCG
CCTGCTCGAGCTGCGCGCGCAGCTCGGCATCCGCTTTCCGGTGTATCTGCTCGTGACGAAGGCGGACTTGCTCGCCGGCT
TCGCCGAATACTTCGGCGGCTTCGGCCGCGCCGAATGCGCGCAGGTGTGGGGCTTCACGTTCCCGCTCGCCGAGAGCGAA
GCGCCCGGCTTCGAGCTGCGCGCGGCGTTCGACCGCGAATACCGGCTGCTGCACCAGCGGCTGAACGACGGGCTGCCGGA
GCTGCTCGCATCGCAGACCGACGCGCGCCAGCGCGAGATGACCTACCTGCTGCCGCAGCAGATCGCCGATCTGCAGGACA
TGCTCGGCCAGTTCGTCGCCGAGGTGTTCTCGGTGTCGAGCTTCGAGCCGATGCCGATGCTGCGCGGCGTCTATCTGACG
AGCGGCACGCAGGAAGGCACCGCGTTCGACCGCGTGATGAGCGGGATCAAGCGCTTCCTGAAGATCGAGGGCGTGCCGCC
CGCCGCGCAGACGGGCTCGTCGGGCCGCAGTTTCTTCCTGAAATCGCTGCTGCAGGATCACATCTTTCGCGAGGCGGCGC
TTGCCGGCAGCAATCTGCGCTGGCATCAGCGGCAGCGTGTGCTGCAGATCGTCGGCTACGCGGCGATCGCGCTGCTGTGC
GTGGCGGTGCTGTTCGCGTGGCTGCGCAGCTACTCGCGCAATCGCGACTATCTCGACGAGGTCGCCGCGCGCGTGCCGGC
GGTCGACGCGCAGATCGGCCGCGCGAAATTCACGGGCGCGGCCGACATCGTGCAACTGCTGCCGGTGCTCGACGAGCTGA
GCGGCCTGCCGAACGCGGGCGGCGTGGACTTGCGGCATCCGCCGCTCGCGTATCGCTGGGGCCTGTTCCAGGGCGAGAAG
ATCGAGGAGGCGAGCGACGCCGTCTACCGGCGCGCGCTCGACGACGTGCTGCTGCCGATCGCCGCGAGCCGGATGGAGCA
GGCACTGCGCGACGCGCGGCCCGACGAGGTCGAGTATGCGTACGCGGCGCTCAAGGCGTACCTGATGCTTTACGACAGCG
CGCACTACGATCCCGCGTTCGTGCAGGCCGTCGTCGATCTCGAGATGGAGCGCGCGCTGCCGGCCGATTTCTCGTCCGCG
CAGCGCAGCGCGCTGCGCGCGCATCTCGGCGCGCTGTTCGGCAATCGCGTCGCGGTGTCGCCGTTTCCGATGAACGAGCG
GCTCGTCGCCGACGTGCGCGAGCGGCTGCGGCAGGTGCCGTTCTCGCAGCGGCTGTATCGGCAGCTCGCGCGCACGCTGC
ACGCGAGCACCGCGTCGTACGATTTCAGCGTCGCGCGCGCGGTGGGGCCGGACGCGTCGCTCGTGTTCCGGCGGCAGAGC
GGCAAGAGCCTCGCCGACGGCGTGCCGGGCCTCTACACGCGCAGCGGCTACCGCAACGTGTTCGCGCCGCGTCTGCCCGG
CGCGATCGATTCGTACGGGCGCGAGGAGGTGTGGGTGCTGAACCTCGGCGCGTCCGAGATCCCGAATCCGGCCGACGCGG
CCGCCTGGGCGCGCGACATCCGGCAGCTCTACCTGAACGACTACATCAAGACCTGGGACGACTATCTGGCCGACATCCGG
CTGCAGCGCACGTCGACGCTCGCGCAGAGCATCCAGGTCGCGCGCACGCTGTCGTCGGCCGATTCGCCGCTCACGCGGCT
GATGGTCGCGCTCGCGCGCGACACGCCGCTCGGCGATGCGCCCGGCGGCGCGCGCAATCTCGCGTCGCGCGCGCAGGACA
AGGTCGACGAGGCGCGCAACTCGCTCGCGCAGATCTTCGCCGGGCAGCCGGGCGGCGAAGCGGGCGCGGCGGCCGCGCCG
CCCGCGAGCCCCGAGCAGATCGTCGACAGCCACTTCGCGGGGCTGCGCGCGTTCGCGCCGGGCGGCGGGGATCAGGCGGC
GTCGTTCGACGCGGTGCTCAAGGCGATCGACGCGCTGTACACGTACCTCACCGCGACCGACGACGCATTGCGCAGCGGCG
CGGCGCCGCCGCCGTCGGACGCGCCCGCGCGGCTGCGCGCGCAGGCGGGCCGGTTGCCGACGCCTGTGCGCGAGGTGCTC
GACGATTTGTCGAACGTCGCGAACGGCAGCATCGCGAGCGTCGAGCAGCGCAACGTCGCGCAGCGCGCGGGCGCGAACGT
CGGCGATTTCTGCCGGCAGGCGATCGCCGGGCGCTACCCGTTCGCGCGCGGCGCGGCGCGCGACGTCGCGCCGTCCGATT
TCGCGCAGCTGTTCGCGGCGGGCGGCCTGATGGACGACTTCTTCCAGAAGAACCTGCAAACGCTCGTCGACACGACCGCG
CATCCATGGCGTTTCAACAACCGCAACGCCGAAGCCGACCCGTCGGCGGCCGCGATGCTCGGCTCGTTCGAGAAGGCGGC
GGTGATCCGCGACGTCTATTTCGGAGGCGGCGCGCGGACCGCGCAGATCAAGGTCGAGATCGTGCCGCTCGAAATGGACC
CGTCGATCTCGGAGATGCTGCTCGACGTCGACGGCCAGATCGTCCGCTACGCGCACGGCCCGCAGGTGCCGACGGCGGTG
CAGTGGCCCGGCACGCGCGGCAGCAATCAGGTGCGGCTGCAGGTGACCGAGCAGTCGGGGGCGACGGGCGGCTTCACGAC
CGAGGGCCCGTGGGCGCTGCACCGGCTGTTCGACCGCGCGGGCGTGTCGGGTGGGCGCGGACCCGAGCAGATGGTCGCGA
GATTCGCGGTCGACGGCAAGCCGATCGTGCTGCAGGTGACGGCGAGCAGCGTTCGCAACCCGTTCCGGTTGCCGCAGATG
GAGTCCTTTACATGTCCTCCGAAGCAATGA