Detailed information of component protein


Summary

Component ID T6CP000585
Component protein type TssL
T6SS ID (Type) T6SS00068 insolico (Type i3)
Strain Burkholderia mallei ATCC 23344
Replicon chromosome II
Sequence Protein sequence (439 a.a.); Nucleotide sequence (1317 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) BMA_RS17985
Coordinate (Strand) 385742..387058 (+)
NCBI ID WP_004190689.1
RefSeq NC_006349
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
DotU PF09850.11 1.1e-74 50..250
OmpA PF00691.22 1.5e-13 318..416
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-230 MNTSSDSFSAGSGGFVPPNPGGAHPAAAPAAGAAAFQPRPGRWAASGTNPLVAAANPLLNLVPQIRSTVHHPNPAWLREHLVVEIRQFEERAQQAGVASEAIIGARYCLCTALDEAAALTPWGGSVWSSHSLLVSFHNETWGGEKFFHLLERLSQQPRQHLDLLELLYFCLALGFEGRYRVLDNGRAQLDAVRRQLAQTIRSVRGEFDPALSPHWRDVVTRDVTRRFTVP
Transmembrane helix 231-253 LWVCVALALLVGFGVFAGLRIAL
Outside 254-438 AGHSDRLFASIDALHVPKLQPAPPAPHPAPAPRVAKFLEPEIAAGLVSVRDEADRSVIVLRGDGLFGSGSTSVIDRYMPVLTRVADALNQVQGNVRVSGYTDDTPVHTARFASNWDLSRERAQAVRSLIAARLDRPERITAEGRGTLDPVAPNDSPANRARNRRVEITLMLAPGSDAARATKEAP


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.6530 - -


  Protein sequence: 439 a.a.    

>T6CP000585 NC_006349:385742-387058 [Burkholderia mallei ATCC 23344] [TssL]
MNTSSDSFSAGSGGFVPPNPGGAHPAAAPAAGAAAFQPRPGRWAASGTNPLVAAANPLLNLVPQIRSTVHHPNPAWLREH
LVVEIRQFEERAQQAGVASEAIIGARYCLCTALDEAAALTPWGGSVWSSHSLLVSFHNETWGGEKFFHLLERLSQQPRQH
LDLLELLYFCLALGFEGRYRVLDNGRAQLDAVRRQLAQTIRSVRGEFDPALSPHWRDVVTRDVTRRFTVPLWVCVALALL
VGFGVFAGLRIALAGHSDRLFASIDALHVPKLQPAPPAPHPAPAPRVAKFLEPEIAAGLVSVRDEADRSVIVLRGDGLFG
SGSTSVIDRYMPVLTRVADALNQVQGNVRVSGYTDDTPVHTARFASNWDLSRERAQAVRSLIAARLDRPERITAEGRGTL
DPVAPNDSPANRARNRRVEITLMLAPGSDAARATKEAP*

  Nucleotide sequence: 1317 bp    

>T6CP000585 NC_006349:385742-387058 [Burkholderia mallei ATCC 23344] [TssL]
ATGAACACTTCTTCCGATTCGTTCTCGGCCGGCTCGGGCGGATTCGTGCCGCCGAATCCGGGCGGCGCGCACCCGGCCGC
CGCGCCGGCGGCGGGTGCGGCCGCGTTTCAGCCGAGGCCGGGCCGCTGGGCGGCGAGCGGCACGAATCCGCTCGTCGCGG
CCGCGAACCCGCTGTTGAACCTCGTGCCGCAGATCCGTTCGACCGTCCATCATCCGAATCCCGCGTGGCTGCGCGAGCAT
CTCGTCGTCGAGATCCGCCAGTTCGAGGAGCGCGCGCAGCAGGCGGGCGTCGCCTCCGAGGCGATCATCGGCGCGCGCTA
CTGCCTGTGCACCGCGCTCGACGAGGCCGCCGCGCTGACGCCGTGGGGCGGCAGCGTATGGTCGTCGCATAGCCTGCTCG
TGTCGTTCCACAACGAGACGTGGGGCGGCGAGAAGTTCTTCCATCTGCTCGAGCGGCTGTCGCAGCAGCCGCGCCAGCAT
CTCGACCTGCTCGAGCTGCTGTACTTCTGCCTCGCGCTCGGCTTCGAGGGGCGCTACCGCGTGCTCGACAACGGCCGCGC
GCAGCTCGACGCGGTGCGCCGCCAGCTCGCGCAGACGATCCGCTCGGTGCGCGGCGAATTCGATCCGGCGCTCTCGCCGC
ATTGGCGCGACGTCGTCACGCGCGACGTCACGCGGCGCTTCACGGTGCCGCTGTGGGTGTGCGTCGCGCTTGCGCTGCTC
GTGGGCTTCGGCGTGTTCGCGGGGCTGCGCATCGCGCTCGCCGGCCATTCGGATCGGCTGTTCGCGTCGATCGACGCGCT
GCACGTGCCGAAGCTGCAGCCGGCGCCGCCCGCGCCGCATCCGGCGCCCGCGCCGCGCGTCGCGAAGTTCCTCGAGCCGG
AGATCGCCGCGGGGCTCGTGAGCGTGCGCGACGAGGCCGACCGCAGCGTGATCGTGCTGCGCGGCGACGGCCTGTTCGGC
TCCGGCTCGACGTCGGTGATCGATCGCTACATGCCGGTGCTCACGCGCGTGGCCGACGCGCTGAACCAGGTGCAGGGCAA
CGTGCGCGTGAGCGGCTACACCGACGACACGCCGGTGCACACCGCGCGCTTCGCGTCGAACTGGGATTTGTCGCGCGAGC
GCGCGCAGGCGGTCCGCAGCCTGATCGCCGCGCGGCTCGACCGCCCCGAGCGGATCACCGCCGAAGGGCGCGGCACGCTC
GATCCCGTCGCGCCGAACGATTCGCCCGCGAACCGCGCGCGCAACCGGCGCGTCGAGATCACGCTGATGCTCGCGCCCGG
CAGCGACGCCGCGCGCGCGACGAAGGAGGCGCCCTGA