Detailed information of component protein


Summary

Component ID T6CP000400
Component protein type TssJ
T6SS ID (Type) T6SS00047 experimental (Type i1)
Strain Helicobacter hepaticus ATCC 51449
Replicon chromosome
Sequence Protein sequence (179 a.a.); Nucleotide sequence (537 bp)
Reference
experimental Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene) HH_RS01235
Coordinate (Strand) 240524..241060 (+)
NCBI ID WP_011115093.1
RefSeq NC_004917
Uniprot ID Q7VJJ4_HELHP
KEGG ID hhe:HH_0249
PDB ID -

Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS-SciN PF12790.9 6.3e-15 35..140

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-3 MRY
Transmembrane helix 4-26 IQLYISFCILACFMGLAISGCSS
Inside 27-178 PVKIQAFNQADSNLNNRGDNVPVTLIIYQLKDISKFKQSSIQDLSTRGNVVLGRDIVDFIKVQVPPNEIDVPVAEFAKKEGKYIGVLALFANPQDKKQKFYKKLNRVFSNKIELNIATEGIMQHKKSKQSQGKDTKADGTAGENNIKDLFNE



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
LIPO(Sec/SPII) 0.9976 pos: 23-24. ISG-CS. MRYIQLYISFCILACFMGLAISG



  Protein sequence: 179 a.a.    

>T6CP000400 NC_004917:240524-241060 [Helicobacter hepaticus ATCC 51449] [TssJ]
MRYIQLYISFCILACFMGLAISGCSSPVKIQAFNQADSNLNNRGDNVPVTLIIYQLKDISKFKQSSIQDLSTRGNVVLGR
DIVDFIKVQVPPNEIDVPVAEFAKKEGKYIGVLALFANPQDKKQKFYKKLNRVFSNKIELNIATEGIMQHKKSKQSQGKD
TKADGTAGENNIKDLFNE*

  Nucleotide sequence: 537 bp    

>T6CP000400 NC_004917:240524-241060 [Helicobacter hepaticus ATCC 51449] [TssJ]
ATGCGATATATCCAGCTTTATATTTCCTTTTGCATTCTCGCTTGCTTTATGGGGCTAGCTATTAGTGGGTGCAGCTCACC
TGTTAAGATACAGGCTTTCAATCAGGCAGATTCTAACCTTAATAATCGTGGCGATAATGTGCCTGTTACGCTCATTATTT
ATCAGCTCAAGGATATTAGTAAATTCAAGCAATCTTCCATACAAGATTTAAGCACACGTGGAAATGTTGTCCTTGGAAGG
GACATTGTAGATTTTATCAAGGTGCAAGTGCCGCCAAATGAAATTGACGTGCCTGTTGCAGAATTTGCAAAAAAAGAGGG
TAAATATATCGGCGTGTTAGCTCTTTTTGCCAATCCGCAGGATAAAAAACAAAAATTCTATAAAAAGCTGAATCGTGTCT
TTTCAAACAAAATCGAGCTTAATATTGCCACTGAAGGCATTATGCAACACAAAAAAAGTAAGCAAAGTCAAGGTAAAGAT
ACAAAGGCTGATGGCACTGCTGGAGAAAACAATATAAAGGATTTGTTCAATGAATAG