Detailed information of component protein


Summary

Component ID T6CP000398
Component protein type TssC
T6SS ID (Type) T6SS00047 experimental (Type i1)
Strain Helicobacter hepaticus ATCC 51449
Replicon chromosome
Sequence Protein sequence (491 a.a.); Nucleotide sequence (1473 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) HH_RS01225
Coordinate (Strand) 238319..239791 (-)
NCBI ID WP_011115091.1
RefSeq NC_004917
Uniprot ID Q7VJJ6_HELHP
KEGG ID hhe:HH_0247
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
VipB PF05943.14 5e-116 64..361
VipB_2 PF18945.2 4.4e-44 376..487
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-490 MSGASANTQTSIKELSIIDSIMQTSRYSKEDESYNIAKMGVVEFITEIVKTDSAENKINKYTLDEMIAHIDDIISRQMDEILHNEQIQQLESTWRGLYFLVERTNFQENIKINLFDVTKQEALEDFEANPDITTATLYKRIYSSEYGQFGGEPVGAILGDYALNASTPDMNFLSKMSSIAAMSHAPFLTSMSAGFFGLDNYAELPKIQDLKALLEGPQYVKWRTFRENEDSKYAGLLVTRFLTRSPYEPQENPIKKFNYKENVHNSHNHLLWGNTIYAFATRLTDSFANYRWCGNIIGPKAGGAVKDLPTYIYESFGTTQSKIPTEVLITDRCEYELAESGFIAFTLRRDSNNAVFFSANAALKPKIFPNTPEGKEAETNYRLGTQLPYIFLVSRLAHYLKVLQREEIGSWKERADIENGLNEWMRQYVSDQENPPAEVRSRRPFRGAKVLVSEIEGEAGWYRINLNVRPHFKFMGANFELSLVGKLDRE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9779 - -


  Protein sequence: 491 a.a.    

>T6CP000398 NC_004917:c239791-238319 [Helicobacter hepaticus ATCC 51449] [TssC]
MSGASANTQTSIKELSIIDSIMQTSRYSKEDESYNIAKMGVVEFITEIVKTDSAENKINKYTLDEMIAHIDDIISRQMDE
ILHNEQIQQLESTWRGLYFLVERTNFQENIKINLFDVTKQEALEDFEANPDITTATLYKRIYSSEYGQFGGEPVGAILGD
YALNASTPDMNFLSKMSSIAAMSHAPFLTSMSAGFFGLDNYAELPKIQDLKALLEGPQYVKWRTFRENEDSKYAGLLVTR
FLTRSPYEPQENPIKKFNYKENVHNSHNHLLWGNTIYAFATRLTDSFANYRWCGNIIGPKAGGAVKDLPTYIYESFGTTQ
SKIPTEVLITDRCEYELAESGFIAFTLRRDSNNAVFFSANAALKPKIFPNTPEGKEAETNYRLGTQLPYIFLVSRLAHYL
KVLQREEIGSWKERADIENGLNEWMRQYVSDQENPPAEVRSRRPFRGAKVLVSEIEGEAGWYRINLNVRPHFKFMGANFE
LSLVGKLDRE*

  Nucleotide sequence: 1473 bp    

>T6CP000398 NC_004917:c239791-238319 [Helicobacter hepaticus ATCC 51449] [TssC]
ATGAGTGGTGCATCAGCAAATACACAAACTTCAATAAAAGAGCTATCTATCATTGATAGTATAATGCAGACAAGTAGATA
TTCAAAGGAAGATGAAAGTTATAATATTGCCAAAATGGGTGTGGTGGAATTTATCACAGAAATAGTCAAAACTGATAGTG
CAGAAAATAAAATCAACAAATACACGCTTGATGAAATGATAGCGCATATTGATGATATTATCTCACGTCAAATGGACGAG
ATATTACACAACGAACAGATTCAGCAATTAGAATCTACATGGAGAGGTTTATATTTTTTAGTAGAACGCACTAATTTTCA
AGAAAATATAAAAATTAATTTGTTTGATGTAACTAAACAAGAGGCTTTAGAGGATTTTGAGGCAAATCCAGATATTACAA
CAGCTACATTATATAAACGTATTTATTCTTCTGAATATGGACAATTTGGTGGCGAGCCTGTAGGTGCAATTCTGGGTGAT
TATGCCTTGAATGCTTCTACGCCTGATATGAATTTTCTTTCTAAGATGTCTTCTATTGCGGCTATGAGCCATGCTCCATT
TTTAACTTCTATGAGTGCTGGTTTTTTTGGGCTTGATAATTATGCGGAACTTCCCAAGATACAGGATTTAAAAGCACTTT
TAGAGGGTCCGCAATATGTAAAATGGCGCACCTTTAGGGAAAATGAAGATTCTAAGTATGCTGGTTTATTGGTTACACGT
TTTCTTACTCGATCTCCTTATGAGCCACAAGAAAATCCTATAAAGAAATTTAATTACAAGGAAAATGTGCATAACTCGCA
TAATCACTTGCTATGGGGAAATACTATTTATGCTTTTGCTACGCGATTGACTGATAGTTTTGCAAATTATCGCTGGTGTG
GAAATATTATAGGACCTAAGGCTGGCGGTGCTGTAAAAGATTTGCCTACTTATATTTATGAAAGCTTTGGCACTACGCAA
TCTAAGATACCAACGGAGGTGCTTATCACAGATAGATGTGAGTATGAGCTTGCAGAATCTGGCTTCATAGCCTTTACGTT
GCGACGTGATAGCAATAATGCAGTATTTTTCTCCGCAAATGCCGCATTAAAGCCAAAAATTTTTCCAAATACGCCTGAAG
GAAAAGAGGCAGAGACAAATTATAGGCTTGGTACGCAGTTACCCTATATATTTTTAGTTTCTCGCCTTGCTCATTATCTT
AAGGTATTGCAAAGAGAAGAAATTGGGAGCTGGAAAGAAAGAGCAGATATAGAGAATGGCTTAAATGAGTGGATGAGGCA
ATATGTTTCAGATCAAGAGAATCCTCCCGCAGAGGTTCGAAGTAGGCGACCATTTAGAGGCGCCAAAGTTCTTGTAAGCG
AGATAGAAGGGGAAGCAGGTTGGTATAGAATAAATTTAAATGTACGACCCCACTTTAAATTTATGGGAGCAAACTTTGAA
CTTTCTTTGGTGGGGAAACTTGACAGAGAATAA