Detailed information of component protein


Summary

Component ID T6CP000153
Component protein type TssM
T6SS ID (Type) T6SS00020 insolico (Type Unknown)
Strain Yersinia pestis CO92
Replicon chromosome
Sequence Protein sequence (1276 a.a.); Nucleotide sequence (3828 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) YPO_RS14605
Coordinate (Strand) 3051683..3055510 (+)
NCBI ID WP_002214843.1
RefSeq NC_003143
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related_N PF14331.8 9.7e-76 253..535
IcmF-related PF06761.14 7.2e-69 586..898
IcmF_C PF06744.14 1.1e-16 1144..1247
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-15 MSYLNRLFSGWAMKR
Transmembrane helix 16-38 ILLVGCFILLAAAIWFLGPFLGF
Outside 39-47 GEARPLESY
Transmembrane helix 48-67 EARIICILLALLLILGFWYG
Inside 68-71 APRF
Transmembrane helix 72-91 VIAAVVACAAVWVIGPFILV
Outside 92-100 GDDHPLTDG
Transmembrane helix 101-123 IRRGIIIAIIAFITLIYGTWCLV
Inside 124-528 KALAKNPALLDNFIKHKKAAKPEAEAELSEVNAMIRNGMNYVRRIHSGIPAWRRFFISNRWRTELPWFMVVGMKGAGKTALILSSGQDFPLPEQLNRIGKENPPTQHCECLFSNDALFLDTSGKYIDDSKDNQTEWTGILKALKKYRPVKAINGVIVAISASDILGKSKADLLNVSATLRTRLDEVRAVLGVRFPVYVTITKLDQISGFDEYFRNLTAEDREQIWGVTFPYNEAKEQSDMPLQQRISHELALLEDRISNNMHVRQQEEYAVADRKGMYALPQDFRMLSQRVTEVLQNVFFASRFDETKFHTTLRGIYFVSSCQPADVELLNNNTLIQKWRNVINHKKPLSPADLSQKSDNEDRFISDVAYGKQYFLKQLFSDVITKDADLVSYNLKVQSKYRFQN
Transmembrane helix 529-548 LLGHAACIGLAVWLVWAFLV
Outside 549-1275 SFQHNEGYLQATGAKLSQLESTVMSYAKTSNEQILPALLNATQQLPEYGTLDVANPELDWRYGLYTGSAISQGANTLYQFFLQKYLFPMVENQSEVTLRKTMHSGQSEEVYAALKLYLMLTGEGKFDRQYMIEHVTQDWQKSGKIEPYEEKSIFVGHLNTLFTLKDWRQYGQPADSELIKQARAILAEKTVTARLWGRIQSRLLADAPANMTLRKMVGEHATQVFTLSDDELLHEGIPGLYTYAGYHEVVKKKLTPLLMLLQEEDRWVMAQSLSSSLDPLTLRQDVLVMYLQGYAAYWKRFLSSVRLISVDADSAEYAQGLSLDIALLRTLVSENSPLLNLARQAVKETTLAEKEKAITDEINIRTQGQLLSQAKKLQETIAFRENKLIKEWVDNRFESLRVFVNGEQSADVTGGNNLSVLQGTQMSRIIGTLNDQYTRFVVYNSAFEYGDIPPLSQDGERIAVESQTWPDPFRNIIAPLLTGSSQKFENKVITHTSKAIDMGVGEICRNTLQGRYPFAESEQIVSLNDFERFFGTDGTVDSYFKKNLESKVDTSSIPWRYKGSVSSEGLAFFEQAAMIRNVLFNTNDGKKMALDFSVSVRYLAPTITQLIMNFDGNTVRYSHGPVTPAFFKWPGLRQGTIVSLTAQRQKASAMPDILFRGPWALLQWADQADEIRDEANGKQTLTYLMGKDRVELEVSGLTHGGETISDLLRDFKCPSVNDMNGIW


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9630 - -


  Protein sequence: 1276 a.a.    

>T6CP000153 NC_003143:3051683-3055510 [Yersinia pestis CO92] [TssM]
MSYLNRLFSGWAMKRILLVGCFILLAAAIWFLGPFLGFGEARPLESYEARIICILLALLLILGFWYGAPRFVIAAVVACA
AVWVIGPFILVGDDHPLTDGIRRGIIIAIIAFITLIYGTWCLVKALAKNPALLDNFIKHKKAAKPEAEAELSEVNAMIRN
GMNYVRRIHSGIPAWRRFFISNRWRTELPWFMVVGMKGAGKTALILSSGQDFPLPEQLNRIGKENPPTQHCECLFSNDAL
FLDTSGKYIDDSKDNQTEWTGILKALKKYRPVKAINGVIVAISASDILGKSKADLLNVSATLRTRLDEVRAVLGVRFPVY
VTITKLDQISGFDEYFRNLTAEDREQIWGVTFPYNEAKEQSDMPLQQRISHELALLEDRISNNMHVRQQEEYAVADRKGM
YALPQDFRMLSQRVTEVLQNVFFASRFDETKFHTTLRGIYFVSSCQPADVELLNNNTLIQKWRNVINHKKPLSPADLSQK
SDNEDRFISDVAYGKQYFLKQLFSDVITKDADLVSYNLKVQSKYRFQNLLGHAACIGLAVWLVWAFLVSFQHNEGYLQAT
GAKLSQLESTVMSYAKTSNEQILPALLNATQQLPEYGTLDVANPELDWRYGLYTGSAISQGANTLYQFFLQKYLFPMVEN
QSEVTLRKTMHSGQSEEVYAALKLYLMLTGEGKFDRQYMIEHVTQDWQKSGKIEPYEEKSIFVGHLNTLFTLKDWRQYGQ
PADSELIKQARAILAEKTVTARLWGRIQSRLLADAPANMTLRKMVGEHATQVFTLSDDELLHEGIPGLYTYAGYHEVVKK
KLTPLLMLLQEEDRWVMAQSLSSSLDPLTLRQDVLVMYLQGYAAYWKRFLSSVRLISVDADSAEYAQGLSLDIALLRTLV
SENSPLLNLARQAVKETTLAEKEKAITDEINIRTQGQLLSQAKKLQETIAFRENKLIKEWVDNRFESLRVFVNGEQSADV
TGGNNLSVLQGTQMSRIIGTLNDQYTRFVVYNSAFEYGDIPPLSQDGERIAVESQTWPDPFRNIIAPLLTGSSQKFENKV
ITHTSKAIDMGVGEICRNTLQGRYPFAESEQIVSLNDFERFFGTDGTVDSYFKKNLESKVDTSSIPWRYKGSVSSEGLAF
FEQAAMIRNVLFNTNDGKKMALDFSVSVRYLAPTITQLIMNFDGNTVRYSHGPVTPAFFKWPGLRQGTIVSLTAQRQKAS
AMPDILFRGPWALLQWADQADEIRDEANGKQTLTYLMGKDRVELEVSGLTHGGETISDLLRDFKCPSVNDMNGIW*

  Nucleotide sequence: 3828 bp    

>T6CP000153 NC_003143:3051683-3055510 [Yersinia pestis CO92] [TssM]
ATGTCTTATTTGAATCGATTGTTTTCTGGCTGGGCCATGAAACGCATATTGCTGGTCGGCTGCTTTATATTGCTGGCTGC
GGCGATATGGTTTCTGGGGCCTTTCCTCGGCTTTGGTGAGGCGCGGCCTCTCGAAAGTTATGAAGCCAGAATTATTTGCA
TCCTGCTGGCACTGCTGCTGATCTTAGGTTTTTGGTACGGCGCACCGCGCTTTGTCATTGCCGCCGTCGTTGCCTGTGCT
GCGGTATGGGTGATTGGCCCATTCATATTAGTTGGTGATGATCATCCTCTGACTGATGGGATCCGTCGCGGCATCATTAT
CGCCATCATTGCATTTATTACACTTATTTATGGCACCTGGTGCTTAGTCAAAGCATTGGCGAAAAATCCAGCGTTACTGG
ATAACTTCATTAAGCACAAGAAAGCGGCCAAGCCTGAAGCGGAGGCTGAACTTTCTGAAGTTAATGCGATGATCCGCAAT
GGCATGAACTATGTGCGCCGTATTCACAGTGGTATTCCGGCCTGGCGACGTTTCTTTATCTCCAACCGTTGGCGCACAGA
ACTGCCTTGGTTCATGGTTGTCGGTATGAAAGGTGCAGGGAAAACCGCCCTTATCCTCTCTTCAGGACAGGACTTTCCTT
TACCTGAGCAGCTGAATCGTATTGGCAAAGAAAACCCACCCACTCAACATTGTGAATGTTTGTTCTCTAATGACGCCCTG
TTTTTAGACACTTCAGGGAAATACATTGATGACAGCAAAGATAATCAGACTGAGTGGACCGGGATATTAAAGGCACTCAA
AAAATATCGTCCGGTTAAGGCAATTAATGGTGTCATTGTTGCGATTTCGGCATCCGATATCTTGGGTAAAAGTAAAGCTG
ATTTACTGAATGTGTCGGCGACGCTACGCACGCGTTTGGATGAGGTTCGTGCGGTCTTGGGCGTCCGTTTCCCGGTGTAT
GTCACGATTACAAAACTGGATCAAATATCGGGTTTTGATGAATATTTCCGTAATTTAACGGCTGAAGATCGCGAGCAAAT
TTGGGGGGTGACTTTCCCTTATAACGAGGCGAAAGAGCAATCCGATATGCCACTTCAGCAACGTATCAGCCATGAGCTGG
CACTGCTTGAGGATCGTATCAGCAATAATATGCACGTCCGCCAGCAGGAAGAGTATGCCGTGGCGGACAGAAAAGGCATG
TATGCACTCCCTCAGGATTTCAGGATGCTCTCCCAGAGGGTAACGGAAGTTTTACAGAATGTTTTCTTCGCCTCACGCTT
TGACGAAACAAAATTTCACACGACCCTGAGAGGGATCTATTTTGTCAGCAGTTGTCAGCCTGCGGATGTTGAACTGTTAA
ATAACAACACGCTGATTCAAAAGTGGCGTAACGTTATTAATCATAAAAAACCGTTATCGCCAGCCGATTTATCACAAAAA
AGTGATAATGAAGATCGGTTTATTAGCGATGTGGCTTACGGGAAACAATATTTCCTCAAGCAGTTGTTTAGCGATGTGAT
TACCAAAGATGCCGACTTAGTCAGCTATAACCTGAAAGTACAATCCAAATACCGTTTTCAGAATCTATTGGGACACGCGG
CTTGTATTGGGTTGGCAGTTTGGCTGGTTTGGGCCTTCTTGGTCAGCTTCCAGCATAACGAGGGGTATTTACAGGCGACC
GGTGCCAAGCTGAGTCAGTTAGAAAGCACGGTGATGAGTTATGCCAAAACGTCCAATGAGCAGATCTTACCTGCGTTATT
GAACGCGACACAGCAGTTACCCGAGTACGGTACGCTGGATGTGGCTAACCCTGAGCTTGACTGGCGTTATGGCTTATATA
CCGGTAGCGCAATCTCACAAGGTGCGAACACGCTCTATCAGTTTTTCTTGCAAAAATATCTCTTCCCAATGGTTGAGAAT
CAGAGTGAGGTTACATTAAGAAAAACGATGCACTCAGGTCAGAGCGAAGAGGTTTATGCCGCGCTGAAGCTTTATTTGAT
GCTGACGGGTGAAGGTAAATTTGATCGTCAATATATGATTGAGCACGTGACCCAAGATTGGCAGAAAAGTGGAAAAATTG
AGCCTTACGAAGAGAAGAGTATTTTCGTCGGTCATTTGAACACGCTGTTTACCCTGAAAGACTGGCGGCAGTATGGGCAA
CCGGCAGACAGTGAACTGATTAAGCAGGCTCGGGCAATACTGGCGGAAAAAACAGTGACCGCCAGACTTTGGGGGCGTAT
TCAATCCCGCTTATTGGCCGATGCCCCTGCCAATATGACGTTACGTAAAATGGTGGGTGAGCACGCGACACAGGTATTCA
CCCTGTCAGATGATGAACTACTGCATGAAGGGATCCCGGGGCTTTATACCTACGCGGGCTACCATGAGGTGGTTAAAAAA
AAACTGACACCTTTGCTGATGTTACTTCAGGAAGAGGATAGGTGGGTGATGGCGCAATCGCTGTCATCTTCTCTTGACCC
CCTGACGTTAAGACAAGATGTTCTGGTGATGTATTTACAAGGGTATGCCGCTTATTGGAAACGCTTTCTCTCCAGTGTTC
GTCTGATTTCTGTCGATGCGGACAGTGCAGAGTATGCTCAAGGGCTGTCTCTGGATATTGCTTTGTTAAGGACGTTAGTT
TCAGAAAATTCACCGCTACTCAATTTAGCCAGGCAGGCGGTAAAAGAAACGACACTCGCCGAAAAAGAAAAAGCCATTAC
TGATGAGATAAACATCAGAACGCAAGGGCAATTACTCAGCCAGGCTAAAAAATTACAAGAAACGATCGCGTTTCGTGAAA
ATAAACTGATTAAAGAGTGGGTTGATAATCGTTTTGAATCCCTGAGAGTCTTTGTTAATGGGGAACAGAGTGCTGATGTC
ACGGGGGGCAATAATCTTTCTGTTCTTCAGGGAACGCAGATGAGCCGAATAATCGGGACATTAAACGATCAATATACCCG
TTTTGTTGTTTATAACAGTGCCTTTGAATATGGCGATATTCCTCCGTTATCCCAGGATGGGGAACGTATTGCGGTGGAAT
CACAAACATGGCCGGATCCGTTTAGAAATATTATTGCACCGTTATTAACGGGCTCATCCCAGAAATTTGAAAATAAAGTG
ATTACTCACACGTCCAAAGCGATTGATATGGGGGTGGGGGAAATTTGCCGGAATACGCTGCAAGGGCGTTACCCATTTGC
TGAAAGTGAGCAAATTGTTAGTTTGAATGATTTTGAGCGTTTCTTCGGTACTGACGGTACGGTGGACAGTTATTTCAAGA
AAAACTTGGAGAGTAAAGTCGACACGTCCTCAATACCTTGGCGTTATAAGGGCAGCGTAAGTAGTGAAGGTTTGGCGTTC
TTTGAACAGGCGGCAATGATCAGAAACGTGCTATTTAATACCAATGACGGTAAAAAAATGGCATTAGATTTTTCCGTATC
AGTGCGTTATTTAGCACCCACTATCACCCAACTTATTATGAACTTTGATGGTAATACTGTGCGTTATTCCCATGGTCCCG
TAACGCCAGCCTTCTTTAAATGGCCGGGTTTACGTCAAGGCACCATTGTCAGTTTAACGGCCCAACGCCAGAAGGCATCC
GCGATGCCCGATATTCTTTTTCGCGGACCTTGGGCACTCTTGCAGTGGGCTGATCAGGCCGATGAAATTCGCGATGAAGC
GAATGGCAAACAGACGCTGACTTATCTCATGGGGAAAGATCGTGTCGAGCTTGAAGTCTCAGGTTTAACGCATGGTGGTG
AAACCATTAGCGATCTGCTGAGAGATTTCAAATGCCCCAGTGTCAATGACATGAATGGTATTTGGTAA