Detailed information of component protein


Summary

Component ID T6CP000135
Component protein type TssK
T6SS ID (Type) T6SS00017 experimental (Type i3)
Strain Yersinia pestis CO92
Replicon chromosome
Sequence Protein sequence (452 a.a.); Nucleotide sequence (1356 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) YPO_RS03575
Coordinate (Strand) 549851..551206 (+)
NCBI ID WP_002210470.1
RefSeq NC_003143
Uniprot ID A0A0E8XIW6_9GAMM, Q66EN8_YERPS, A0A0U1R2F9_YERP3, A0A0E1NLS2_YERPA, A0A0H2YDU8_YERPN, A0A0H3B5M5_YERPY, A0A5P8YL23_YERPE, A0A3G5IS42_YERPU
KEGG ID ypn:YPN_0388, ypc:BZ23_130, ypu:BZ21_4036, ypq:DJ40_1715, ypr:BZ20_1441, ypa:YPA_3582, ype:YPO0513, ypi:YpsIP31758_3423, ypo:BZ17_1903, ypy:YPK_3552, yps:YPTB0654
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_VasE PF05936.14 7.7e-119 19..444
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-451 MLPKQRVAWVEGMLMEPQHFQQQERYLEHLTEMRARSLSALAWGFHSLSINQGLLDQGKIALNQASGVFPDGTPFHMAGDEPLPLPFDPGENCQGSVVCLSVLMDIPGNTYIDLKKSNQGSRFVALDAEVQDRNHGVAAEGTPLIATLQLGQLQSKLTLRASVSDAESMLPVAYIKERTRDGRLILDDNFLPPMLDFRAIGWIDNAVTELLGLIVQRLESVYRPDVTLSVGGLSELLELLLLQTLSEYNLKISHVLMQKQVHPEQLFQLLLGLLGRLSTIPGGEKPWSRQDLLYTHHEPHNGYFSLFAALRRALSLVIEAPAVALPFIERGDNIYLCQNDSQLRLEKLIFTVSSKLPSETIRTYFPAQTKLGPVEKIVQLIDLQLPGARMIPMSSPPRYIPYYPNSVYFEVDHDDPMYKEMMSGSAIALSIVGDFPELRFEVWGLRQGRLG


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9826 - -


  Protein sequence: 452 a.a.    

>T6CP000135 NC_003143:549851-551206 [Yersinia pestis CO92] [TssK]
MLPKQRVAWVEGMLMEPQHFQQQERYLEHLTEMRARSLSALAWGFHSLSINQGLLDQGKIALNQASGVFPDGTPFHMAGD
EPLPLPFDPGENCQGSVVCLSVLMDIPGNTYIDLKKSNQGSRFVALDAEVQDRNHGVAAEGTPLIATLQLGQLQSKLTLR
ASVSDAESMLPVAYIKERTRDGRLILDDNFLPPMLDFRAIGWIDNAVTELLGLIVQRLESVYRPDVTLSVGGLSELLELL
LLQTLSEYNLKISHVLMQKQVHPEQLFQLLLGLLGRLSTIPGGEKPWSRQDLLYTHHEPHNGYFSLFAALRRALSLVIEA
PAVALPFIERGDNIYLCQNDSQLRLEKLIFTVSSKLPSETIRTYFPAQTKLGPVEKIVQLIDLQLPGARMIPMSSPPRYI
PYYPNSVYFEVDHDDPMYKEMMSGSAIALSIVGDFPELRFEVWGLRQGRLG*

  Nucleotide sequence: 1356 bp    

>T6CP000135 NC_003143:549851-551206 [Yersinia pestis CO92] [TssK]
ATGCTGCCAAAACAACGTGTTGCTTGGGTGGAAGGGATGCTGATGGAACCCCAGCATTTTCAACAACAGGAACGATATCT
AGAACATTTAACTGAAATGCGGGCACGTAGCCTCAGCGCGCTGGCATGGGGCTTCCATAGCCTAAGTATCAATCAAGGGC
TGCTGGATCAGGGCAAGATCGCCCTCAATCAGGCCAGTGGTGTTTTCCCTGACGGTACACCTTTTCATATGGCGGGTGAT
GAGCCATTACCGCTACCTTTTGATCCGGGGGAGAACTGCCAAGGCAGTGTCGTGTGCCTTTCGGTCCTGATGGATATACC
CGGCAATACCTATATTGATCTGAAGAAGAGCAACCAAGGTAGCCGTTTCGTTGCGCTGGATGCTGAAGTTCAAGACAGAA
ACCATGGCGTCGCTGCTGAAGGAACGCCATTGATCGCCACCCTTCAACTGGGGCAATTGCAATCCAAGCTCACCTTACGT
GCCAGCGTCAGTGATGCAGAATCGATGCTGCCCGTAGCCTATATCAAAGAGCGCACCCGCGATGGGCGTCTGATTCTGGA
TGATAACTTCCTGCCACCCATGTTGGATTTTCGCGCCATAGGGTGGATCGATAATGCGGTAACCGAATTGCTAGGGTTGA
TCGTTCAGCGACTGGAATCGGTTTACCGGCCAGATGTGACGCTCTCAGTCGGTGGGTTATCGGAGTTACTGGAACTGCTA
TTACTGCAAACACTCAGTGAATATAACCTAAAGATTTCACATGTGTTGATGCAAAAACAGGTACACCCTGAGCAGTTGTT
CCAATTATTGCTTGGGTTGTTGGGGCGTCTCAGTACTATCCCTGGCGGAGAAAAACCGTGGTCGAGGCAGGATCTGCTCT
ATACGCATCATGAACCGCACAACGGGTATTTCTCGCTGTTTGCCGCCTTACGGCGCGCACTCTCACTGGTGATCGAAGCA
CCGGCAGTGGCGCTACCGTTTATCGAACGTGGCGACAATATTTACCTGTGCCAGAACGATTCACAACTGCGTCTGGAAAA
ACTGATCTTCACCGTCAGTTCCAAACTGCCTTCCGAGACCATTCGCACTTACTTCCCGGCGCAAACCAAACTGGGGCCGG
TGGAGAAAATTGTACAGTTGATCGACCTGCAATTGCCTGGCGCACGGATGATCCCGATGTCATCACCGCCAAGATATATT
CCTTATTACCCGAATAGCGTCTATTTCGAAGTTGACCATGATGATCCTATGTATAAAGAAATGATGTCTGGTTCAGCTAT
CGCACTCAGCATCGTGGGTGATTTCCCTGAGTTGCGTTTTGAAGTATGGGGCTTGCGACAAGGAAGGCTCGGATGA