Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ABD408_RS08240 Genome accession   NZ_CP155735
Coordinates   1653845..1654396 (-) Length   183 a.a.
NCBI ID   WP_080262832.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 4958/15     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1648845..1659396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABD408_RS08215 (ABD408_08185) - 1650211..1651056 (+) 846 WP_002982833.1 mechanosensitive ion channel family protein -
  ABD408_RS08220 (ABD408_08190) - 1651121..1651681 (-) 561 WP_002988142.1 TIGR01440 family protein -
  ABD408_RS08225 (ABD408_08195) - 1651695..1652165 (-) 471 WP_002988139.1 ECF transporter S component -
  ABD408_RS08230 (ABD408_08200) - 1652155..1652919 (-) 765 WP_002982821.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  ABD408_RS08235 (ABD408_08205) truA 1652909..1653658 (-) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  ABD408_RS08240 (ABD408_08210) comX/sigX/comX2/sigX2 1653845..1654396 (-) 552 WP_080262832.1 competence protein ComX Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22280.14 Da        Isoelectric Point: 10.1972

>NTDB_id=998928 ABD408_RS08240 WP_080262832.1 1653845..1654396(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain 4958/15]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLKRYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=998928 ABD408_RS08240 WP_080262832.1 1653845..1654396(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain 4958/15]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAAAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAAGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment