Detailed information NTG0997592

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: ABC806_RS07525
• Genome accession: NZ_CP155539
• Coordinates: 1448882..1449472 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613477.1
• Uniprot ID: A0A064BX72
• Organism: Streptococcus pneumoniae TIGR4
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1440846..1449472	1448882..1449472	within	0

Gene organization within MGE regions

Location: 1440846..1449472

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC806_RS07480 (ABC806_07470)	ftsE	1440846..1441538 (-)	693	WP_000022268.1	cell division ATP-binding protein FtsE	-
ABC806_RS07490 (ABC806_07480)	-	1442759..1443415 (-)	657	WP_000268636.1	CBS domain-containing protein	-
ABC806_RS07495 (ABC806_07485)	-	1443723..1444433 (-)	711	WP_000062224.1	ATP-binding cassette domain-containing protein	-
ABC806_RS07500 (ABC806_07490)	-	1444433..1445197 (-)	765	WP_001186003.1	ABC transporter ATP-binding protein	-
ABC806_RS07505 (ABC806_07495)	-	1445197..1446153 (-)	957	WP_000662293.1	branched-chain amino acid ABC transporter permease	-
ABC806_RS07510 (ABC806_07500)	-	1446157..1447026 (-)	870	WP_000941421.1	branched-chain amino acid ABC transporter permease	-
ABC806_RS07515 (ABC806_07505)	-	1447294..1448454 (-)	1161	WP_000726149.1	ABC transporter substrate-binding protein	-
ABC806_RS07520 (ABC806_07510)	-	1448555..1448803 (-)	249	WP_000462126.1	YlbG family protein	-
ABC806_RS07525 (ABC806_07515)	clpP	1448882..1449472 (-)	591	WP_000613477.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21358.36 Da
• Isoelectric Point: 4.4910

>NTDB_id=997592 ABC806_RS07525 WP_000613477.1 1448882..1449472(-) (clpP) [Streptococcus pneumoniae TIGR4]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=997592 ABC806_RS07525 WP_000613477.1 1448882..1449472(-) (clpP) [Streptococcus pneumoniae TIGR4]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A064BX72

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	100	100	1
clpP	Streptococcus pneumoniae D39	100	100	1
clpP	Streptococcus pneumoniae R6	100	100	1
clpP	Streptococcus pneumoniae TIGR4	100	100	1
clpP	Streptococcus thermophilus LMG 18311	92.821	99.49	0.923
clpP	Streptococcus thermophilus LMD-9	92.821	99.49	0.923
clpP	Streptococcus pyogenes JRS4	90.769	99.49	0.903
clpP	Streptococcus pyogenes MGAS315	90.769	99.49	0.903
clpP	Streptococcus mutans UA159	85.714	100	0.857
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571