Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ABC811_RS07720 Genome accession   NZ_CP155535
Coordinates   1490681..1492171 (+) Length   496 a.a.
NCBI ID   WP_001818755.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PJ755/1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1485681..1497171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC811_RS07680 (ABC811_07675) - 1486683..1487497 (+) 815 Protein_1519 IS5-like element IS1515 family transposase -
  ABC811_RS07685 (ABC811_07680) - 1487511..1487906 (-) 396 WP_000846569.1 hypothetical protein -
  ABC811_RS07690 (ABC811_07685) - 1487903..1488067 (-) 165 WP_000727118.1 hypothetical protein -
  ABC811_RS07695 (ABC811_07690) - 1488366..1488485 (-) 120 WP_001844187.1 PncF family bacteriocin immunity protein -
  ABC811_RS07700 (ABC811_07695) blpU 1488488..1488718 (-) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  ABC811_RS07705 (ABC811_07700) blpJ 1488787..1489056 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  ABC811_RS07710 (ABC811_07705) blpI 1489523..1489720 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ABC811_RS07715 (ABC811_07710) comA/nlmT 1490002..1490589 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  ABC811_RS07720 (ABC811_07715) comA/nlmT 1490681..1492171 (+) 1491 WP_001818755.1 peptide cleavage/export ABC transporter Regulator
  ABC811_RS07725 (ABC811_07720) - 1492182..1493543 (+) 1362 WP_001069071.1 bacteriocin secretion accessory protein -
  ABC811_RS07730 (ABC811_07725) blpC 1493600..1493755 (+) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  ABC811_RS07735 (ABC811_07730) - 1493799..1495139 (-) 1341 WP_001099892.1 sensor histidine kinase -
  ABC811_RS07740 (ABC811_07735) comE/blpR 1495153..1495890 (-) 738 WP_001219141.1 response regulator transcription factor Regulator
  ABC811_RS07745 (ABC811_07740) - 1495895..1496233 (-) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  ABC811_RS07750 (ABC811_07745) - 1496510..1496839 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56059.95 Da        Isoelectric Point: 6.6428

>NTDB_id=997331 ABC811_RS07720 WP_001818755.1 1490681..1492171(+) (comA/nlmT) [Streptococcus pneumoniae strain PJ755/1]
MSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLL
AQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKS
FKLSKYSILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLPSAKVANNRLNEV
YLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHI
SINHQDIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGL
SGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSH
QELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=997331 ABC811_RS07720 WP_001818755.1 1490681..1492171(+) (comA/nlmT) [Streptococcus pneumoniae strain PJ755/1]
ATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCA
TATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTA
TTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTG
GCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACC
TTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTG
AAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCC
TTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATG
GTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTA
CAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCCATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTC
TATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGA
CCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCC
TAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATT
TCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTA
TATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTT
GTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTA
TCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGACGAAGCTAC
TAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAG
CCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCAC
CAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(279-428)

ABC transporter transmembrane region (ABC_membrane)

(2-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.333

99.798

0.732
  comA Streptococcus gordonii str. Challis substr. CH1

67.002

100

0.671
  comA Streptococcus mitis NCTC 12261

67.137

100

0.671
  comA Streptococcus pneumoniae Rx1

66.734

100

0.667
  comA Streptococcus pneumoniae D39

66.734

100

0.667
  comA Streptococcus pneumoniae R6

66.734

100

0.667
  comA Streptococcus mitis SK321

66.532

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.532

100

0.665

Multiple sequence alignment