Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ABC810_RS08710 Genome accession   NZ_CP155532
Coordinates   1718905..1720548 (+) Length   547 a.a.
NCBI ID   WP_075270826.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SP264     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1713905..1725548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC810_RS08670 (ABC810_08660) - 1714392..1714775 (-) 384 WP_000877381.1 hypothetical protein -
  ABC810_RS08675 (ABC810_08665) - 1715404..1715723 (-) 320 Protein_1669 immunity protein -
  ABC810_RS08680 (ABC810_08670) - 1716243..1716362 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  ABC810_RS08685 (ABC810_08675) cipB 1716466..1716615 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  ABC810_RS08690 (ABC810_08680) blpK 1716859..1717107 (-) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  ABC810_RS08695 (ABC810_08685) blpJ 1717176..1717445 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  ABC810_RS08700 (ABC810_08690) blpI 1717912..1718109 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ABC810_RS08705 (ABC810_08695) comA/nlmT 1718391..1718978 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  ABC810_RS08710 (ABC810_08700) comA/nlmT 1718905..1720548 (+) 1644 WP_075270826.1 peptide cleavage/export ABC transporter Regulator
  ABC810_RS08715 (ABC810_08705) - 1720559..1721920 (+) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  ABC810_RS08720 (ABC810_08710) blpC 1721977..1722105 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  ABC810_RS08725 (ABC810_08715) - 1722176..1723516 (-) 1341 WP_001017642.1 sensor histidine kinase -
  ABC810_RS08730 (ABC810_08720) comE/blpR 1723530..1724267 (-) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  ABC810_RS08735 (ABC810_08725) - 1724272..1724610 (-) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  ABC810_RS08740 (ABC810_08730) - 1724886..1725215 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61643.61 Da        Isoelectric Point: 6.5088

>NTDB_id=997129 ABC810_RS08710 WP_075270826.1 1718905..1720548(+) (comA/nlmT) [Streptococcus pneumoniae strain SP264]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=997129 ABC810_RS08710 WP_075270826.1 1718905..1720548(+) (comA/nlmT) [Streptococcus pneumoniae strain SP264]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGATTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGCGTCTTACTGGCACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGACATATTTCTATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCACAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(330-479)

ABC transporter transmembrane region (ABC_membrane)

(2-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.077

99.817

0.729
  comA Streptococcus mitis NCTC 12261

67.824

100

0.678
  comA Streptococcus pneumoniae D39

67.459

100

0.675
  comA Streptococcus pneumoniae R6

67.459

100

0.675
  comA Streptococcus pneumoniae Rx1

67.459

100

0.675
  comA Streptococcus mitis SK321

67.276

100

0.673
  comA Streptococcus gordonii str. Challis substr. CH1

67.153

100

0.673
  comA Streptococcus pneumoniae TIGR4

67.093

100

0.671

Multiple sequence alignment