Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   ABC810_RS00040 Genome accession   NZ_CP155532
Coordinates   6056..6181 (+) Length   41 a.a.
NCBI ID   WP_000799694.1    Uniprot ID   Q9WW44
Organism   Streptococcus pneumoniae strain SP264     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 1056..11181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC810_RS00015 (ABC810_00015) dnaA 1541..2902 (-) 1362 WP_000660615.1 chromosomal replication initiator protein DnaA -
  ABC810_RS00020 (ABC810_00020) spo0J 3115..3873 (-) 759 WP_000410383.1 ParB/RepB/Spo0J family partition protein Regulator
  ABC810_RS00025 (ABC810_00025) htrA 3931..5112 (-) 1182 WP_000681598.1 S1C family serine protease Regulator
  ABC810_RS00030 (ABC810_00030) rlmH 5295..5774 (+) 480 WP_000695929.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ABC810_RS00040 (ABC810_00040) comC/comC2 6056..6181 (+) 126 WP_000799694.1 competence-stimulating peptide ComC Regulator
  ABC810_RS00045 (ABC810_00045) comD/comD2 6202..7527 (+) 1326 WP_000364843.1 competence system sensor histidine kinase ComD Regulator
  ABC810_RS00050 (ABC810_00050) comE 7524..8276 (+) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  ABC810_RS00065 (ABC810_00065) - 8519..9061 (-) 543 WP_001158266.1 TetR/AcrR family transcriptional regulator -
  ABC810_RS00070 (ABC810_00070) - 9240..10842 (+) 1603 Protein_10 YhgE/Pip domain-containing protein -

Sequence


Protein


Download         Length: 41 a.a.        Molecular weight: 4892.93 Da        Isoelectric Point: 10.9061

>NTDB_id=997067 ABC810_RS00040 WP_000799694.1 6056..6181(+) (comC/comC2) [Streptococcus pneumoniae strain SP264]
MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=997067 ABC810_RS00040 WP_000799694.1 6056..6181(+) (comC/comC2) [Streptococcus pneumoniae strain SP264]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCTTTGAAGGAAAAAGACTTACAAAATATTAAAGGTGGGGAGATGAG
GATTTCAAGAATCATCCTTGATTTTCTTTTCCTACGAAAAAAGTAA

Domains


Predicted by InterproScan.

(1-29)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q9WW44

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

97.561

100

0.976

  comC/comC2 Streptococcus pneumoniae TIGR4

97.561

100

0.976

  comC/comC1 Streptococcus pneumoniae R6

78.049

100

0.78

  comC/comC1 Streptococcus pneumoniae G54

78.049

100

0.78

  comC/comC1 Streptococcus pneumoniae D39

78.049

100

0.78

  comC/comC1 Streptococcus pneumoniae Rx1

78.049

100

0.78

  comC Streptococcus mitis SK321

75.61

100

0.756

  comC Streptococcus mitis NCTC 12261

60

97.561

0.585


Multiple sequence alignment