Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   AAVB74_RS04425 Genome accession   NZ_CP154920
Coordinates   850721..851314 (-) Length   197 a.a.
NCBI ID   WP_003228214.1    Uniprot ID   A0A199WEF2
Organism   Bacillus subtilis strain FUA2232     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 845721..856314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAVB74_RS04410 (AAVB74_04410) mdxK 846036..848309 (+) 2274 WP_345805854.1 maltose phosphorylase -
  AAVB74_RS04415 (AAVB74_04415) malL 848302..849987 (+) 1686 WP_345805855.1 oligo-1,6-glucosidase -
  AAVB74_RS04420 (AAVB74_04420) pgmB 849984..850658 (+) 675 WP_345805856.1 beta-phosphoglucomutase -
  AAVB74_RS04425 (AAVB74_04425) clpP 850721..851314 (-) 594 WP_003228214.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  AAVB74_RS04435 (AAVB74_04435) - 852974..853174 (-) 201 WP_015483735.1 hypothetical protein -
  AAVB74_RS04440 (AAVB74_04440) - 853551..853865 (+) 315 WP_015483734.1 hypothetical protein -
  AAVB74_RS04445 (AAVB74_04445) - 853921..854589 (+) 669 WP_148343218.1 DUF5819 family protein -
  AAVB74_RS04450 (AAVB74_04450) - 854611..855960 (+) 1350 WP_345805857.1 DCC1-like thiol-disulfide oxidoreductase family protein -

Sequence

Protein


Download         Length: 197 a.a.        Molecular weight: 21682.00 Da        Isoelectric Point: 4.9416

>NTDB_id=995436 AAVB74_RS04425 WP_003228214.1 850721..851314(-) (clpP) [Bacillus subtilis strain FUA2232]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide


Download         Length: 594 bp        

>NTDB_id=995436 AAVB74_RS04425 WP_003228214.1 850721..851314(-) (clpP) [Bacillus subtilis strain FUA2232]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAAGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGTGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

100

100

1
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.617

95.431

0.655
  clpP Streptococcus thermophilus LMG 18311

58.163

99.492

0.579
  clpP Streptococcus thermophilus LMD-9

58.163

99.492

0.579
  clpP Streptococcus pneumoniae D39

57.812

97.462

0.563
  clpP Streptococcus pneumoniae Rx1

57.812

97.462

0.563
  clpP Streptococcus pneumoniae R6

57.812

97.462

0.563
  clpP Streptococcus pneumoniae TIGR4

57.812

97.462

0.563
  clpP Lactococcus lactis subsp. cremoris KW2

57.895

96.447

0.558
  clpP Streptococcus pyogenes JRS4

56.122

99.492

0.558
  clpP Streptococcus pyogenes MGAS315

56.122

99.492

0.558
  clpP Streptococcus mutans UA159

54.822

100

0.548
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

55.789

96.447

0.538

Multiple sequence alignment