Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | SP4011_RS08155 | Genome accession | NZ_AP026968 |
| Coordinates | 1573005..1573595 (-) | Length | 196 a.a. |
| NCBI ID | WP_050242379.1 | Uniprot ID | - |
| Organism | Streptococcus parapneumoniae strain SP4011 | ||
| Function | degradation of ComX; degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1565068..1574954 | 1573005..1573595 | within | 0 |
Gene organization within MGE regions
Location: 1565068..1574954
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SP4011_RS08110 (SP4011_15580) | ftsE | 1565068..1565760 (-) | 693 | WP_000022265.1 | cell division ATP-binding protein FtsE | - |
| SP4011_RS08120 (SP4011_15600) | - | 1566980..1567636 (-) | 657 | WP_338618713.1 | CBS domain-containing protein | - |
| SP4011_RS08125 (SP4011_15610) | - | 1567996..1568706 (-) | 711 | WP_000062219.1 | ABC transporter ATP-binding protein | - |
| SP4011_RS08130 (SP4011_15620) | - | 1568706..1569470 (-) | 765 | WP_050242381.1 | ABC transporter ATP-binding protein | - |
| SP4011_RS08135 (SP4011_15630) | - | 1569470..1570426 (-) | 957 | WP_050276357.1 | branched-chain amino acid ABC transporter permease | - |
| SP4011_RS08140 (SP4011_15640) | - | 1570430..1571299 (-) | 870 | WP_050266011.1 | branched-chain amino acid ABC transporter permease | - |
| SP4011_RS08145 (SP4011_15650) | - | 1571416..1572576 (-) | 1161 | WP_338618722.1 | ABC transporter substrate-binding protein | - |
| SP4011_RS08150 (SP4011_15660) | - | 1572660..1572926 (-) | 267 | WP_050223575.1 | YlbG family protein | - |
| SP4011_RS08155 (SP4011_15670) | clpP | 1573005..1573595 (-) | 591 | WP_050242379.1 | ATP-dependent Clp protease proteolytic subunit ClpP | Regulator |
| SP4011_RS08160 (SP4011_15680) | upp | 1573769..1574398 (-) | 630 | WP_000515975.1 | uracil phosphoribosyltransferase | - |
| SP4011_RS08165 (SP4011_15690) | - | 1574487..1574954 (-) | 468 | WP_000136973.1 | deoxycytidylate deaminase | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21363.36 Da Isoelectric Point: 4.5912
>NTDB_id=99129 SP4011_RS08155 WP_050242379.1 1573005..1573595(-) (clpP) [Streptococcus parapneumoniae strain SP4011]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Nucleotide
Download Length: 591 bp
>NTDB_id=99129 SP4011_RS08155 WP_050242379.1 1573005..1573595(-) (clpP) [Streptococcus parapneumoniae strain SP4011]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTTAAAGACCGCAT
CATTATGCTGACAGGTCCCGTTGAAGACAATATGGCCAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTTGATACTATGAAC
TTTATCAAGGCAGATGTCCAAACCATCGTTATGGGAATGGCTGCATCTATGGGGACGGTCATTGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTATATGATTCACCAACCAATGGGCGGTACAGGTGGAGGTACTCAACAAA
CTGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTCATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGTGCCCAAGAAACACTCGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTTAAAGACCGCAT
CATTATGCTGACAGGTCCCGTTGAAGACAATATGGCCAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTTGATACTATGAAC
TTTATCAAGGCAGATGTCCAAACCATCGTTATGGGAATGGCTGCATCTATGGGGACGGTCATTGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTATATGATTCACCAACCAATGGGCGGTACAGGTGGAGGTACTCAACAAA
CTGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTCATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGTGCCCAAGAAACACTCGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pneumoniae Rx1 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus pneumoniae D39 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus pneumoniae R6 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus pneumoniae TIGR4 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus thermophilus LMG 18311 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus thermophilus LMD-9 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus pyogenes JRS4 |
91.795 |
99.49 |
0.913 |
| clpP | Streptococcus pyogenes MGAS315 |
91.795 |
99.49 |
0.913 |
| clpP | Streptococcus mutans UA159 |
86.667 |
99.49 |
0.862 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
85.128 |
99.49 |
0.847 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
84.615 |
99.49 |
0.842 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.854 |
97.959 |
0.577 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.031 |
98.469 |
0.571 |