NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	ECHMS174_RS02255	Genome accession	NZ_LM993812
Coordinates	455900..456523 (+)	Length	207 a.a.
NCBI ID	WP_000122253.1	Uniprot ID	A0A370V1H3
Organism	Escherichia coli strain K-12 substr. HMS174
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 450900..461523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECHMS174_RS02230 (ECHMS174_00440)	ampG	451293..452768 (-)	1476	WP_000098429.1	muropeptide MFS transporter AmpG	-
ECHMS174_RS02235 (ECHMS174_00441)	yajG	452812..453390 (-)	579	WP_001295326.1	lipoprotein	-
ECHMS174_RS02240 (ECHMS174_00442)	bolA	453695..454012 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
ECHMS174_RS02250 (ECHMS174_00443)	tig	454356..455654 (+)	1299	WP_001198386.1	trigger factor	-
ECHMS174_RS02255 (ECHMS174_00444)	clpP	455900..456523 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
ECHMS174_RS02260 (ECHMS174_00445)	clpX	456649..457923 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
ECHMS174_RS02265 (ECHMS174_00447)	lon	458111..460465 (+)	2355	WP_001295325.1	endopeptidase La	-
ECHMS174_RS02270 (ECHMS174_00448)	hupB	460656..460946 (+)	291	WP_254892905.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

Download Length: 207 a.a. Molecular weight: 23186.65 Da Isoelectric Point: 5.6032

                                >NTDB_id=990763 ECHMS174_RS02255 WP_000122253.1 455900..456523(+) (clpP) [Escherichia coli strain K-12 substr. HMS174]

MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP

GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK

GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide

Download Length: 624 bp

                                >NTDB_id=990763 ECHMS174_RS02255 WP_000122253.1 455900..456523(+) (clpP) [Escherichia coli strain K-12 substr. HMS174]

ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGCGG

TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG

CTAACCTGATTGTGGCGCAGATGCTGTTCCTGGAAGCGGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCCCCA

GGCGGGGTGATCACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG

CCAGGCGGCCTCGATGGGCGCTTTCTTGCTGACCGCAGGGGCAAAAGGTAAACGTTTTTGCCTGCCGAATTCGCGCGTGA

TGATTCACCAACCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA

GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT

CCTTTCCGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(26-205)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A370V1H3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	69.792	92.754	0.647
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	90.821	0.623
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	93.72	0.531
clpP	Streptococcus pneumoniae R6	55.155	93.72	0.517
clpP	Streptococcus pneumoniae TIGR4	55.155	93.72	0.517
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.155	93.72	0.517
clpP	Streptococcus pneumoniae Rx1	55.155	93.72	0.517
clpP	Streptococcus pneumoniae D39	55.155	93.72	0.517
clpP	Streptococcus thermophilus LMD-9	54.922	93.237	0.512
clpP	Streptococcus thermophilus LMG 18311	54.922	93.237	0.512
clpP	Streptococcus pyogenes JRS4	55.263	91.787	0.507
clpP	Streptococcus pyogenes MGAS315	55.263	91.787	0.507
clpP	Streptococcus mutans UA159	53.886	93.237	0.502

Detailed information NTG0990763