Detailed information NTG0098817

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: R8568_RS06225
• Genome accession: NZ_AP026931
• Coordinates: 1237705..1238355 (-)
• Length: 216 a.a.
• NCBI ID: WP_000387339.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701541
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1232705..1243355

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8568_RS06205 (PC1520_12330)	-	1233309..1234493 (-)	1185	WP_000652066.1	ABC transporter permease	-
R8568_RS06210 (PC1520_12340)	-	1234490..1235083 (-)	594	WP_000933549.1	ATP-binding cassette domain-containing protein	-
R8568_RS06215 (PC1520_12350)	-	1235115..1235339 (-)	225	WP_001850593.1	hypothetical protein	-
R8568_RS06220 (PC1520_12360)	comEC/celB	1235481..1237721 (-)	2241	WP_000942397.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R8568_RS06225 (PC1520_12370)	comEA/celA/cilE	1237705..1238355 (-)	651	WP_000387339.1	ComEA family DNA-binding protein	Machinery gene
R8568_RS06230 (PC1520_12380)	-	1238423..1238992 (-)	570	WP_000443776.1	GNAT family N-acetyltransferase	-
R8568_RS06235	ald	1239169..1240280 (+)	1112	Protein_1237	alanine dehydrogenase	-
R8568_RS06240	-	1240581..1240906 (-)	326	Protein_1238	TfoX/Sxy family protein	-
R8568_RS06245 (PC1520_12430)	-	1240909..1241409 (-)	501	WP_000566982.1	GNAT family N-acetyltransferase	-
R8568_RS06250 (PC1520_12440)	-	1241602..1242570 (-)	969	WP_000658183.1	PhoH family protein	-
R8568_RS06255 (PC1520_12450)	-	1242656..1242871 (-)	216	WP_001232082.1	YozE family protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23228.71 Da
• Isoelectric Point: 6.9977

>NTDB_id=98817 R8568_RS06225 WP_000387339.1 1237705..1238355(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701541]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKKEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=98817 R8568_RS06225 WP_000387339.1 1237705..1238355(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701541]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGAAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae D39	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae R6	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.759	100	0.968
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	89.815	100	0.898
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361