Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   NST80_RS05530 Genome accession   NZ_CP152039
Coordinates   1236991..1237698 (-) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus sp. FSL K6-1323     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1231991..1242698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS05505 (NST80_05505) - 1232659..1233873 (+) 1215 WP_014633201.1 aminoacyltransferase -
  NST80_RS05510 (NST80_05510) - 1233975..1234251 (-) 277 Protein_1032 ISL3 family transposase -
  NST80_RS05515 (NST80_05515) - 1234422..1234781 (-) 360 WP_045769141.1 YbaN family protein -
  NST80_RS05520 (NST80_05520) vicX 1234840..1235652 (-) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  NST80_RS05525 (NST80_05525) vicK 1235658..1236998 (-) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NST80_RS05530 (NST80_05530) vicR 1236991..1237698 (-) 708 WP_002884978.1 response regulator YycF Regulator
  NST80_RS05535 (NST80_05535) - 1237983..1238750 (+) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  NST80_RS05540 (NST80_05540) - 1238760..1239593 (+) 834 WP_013990682.1 transporter substrate-binding domain-containing protein -
  NST80_RS05545 (NST80_05545) - 1239611..1240309 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  NST80_RS05550 (NST80_05550) - 1240321..1240971 (+) 651 WP_045769140.1 amino acid ABC transporter permease -
  NST80_RS05555 (NST80_05555) - 1241158..1241925 (+) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=986325 NST80_RS05530 WP_002884978.1 1236991..1237698(-) (vicR) [Streptococcus sp. FSL K6-1323]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=986325 NST80_RS05530 WP_002884978.1 1236991..1237698(-) (vicR) [Streptococcus sp. FSL K6-1323]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment