Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   NST80_RS05525 Genome accession   NZ_CP152039
Coordinates   1235658..1236998 (-) Length   446 a.a.
NCBI ID   WP_002885062.1    Uniprot ID   A0A0F3HCD0
Organism   Streptococcus sp. FSL K6-1323     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1230658..1241998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS05495 (NST80_05495) - 1230808..1231674 (-) 867 WP_183138214.1 GNAT family N-acetyltransferase -
  NST80_RS05500 (NST80_05500) yidA 1231853..1232659 (+) 807 WP_004182607.1 sugar-phosphatase -
  NST80_RS05505 (NST80_05505) - 1232659..1233873 (+) 1215 WP_014633201.1 aminoacyltransferase -
  NST80_RS05510 (NST80_05510) - 1233975..1234251 (-) 277 Protein_1032 ISL3 family transposase -
  NST80_RS05515 (NST80_05515) - 1234422..1234781 (-) 360 WP_045769141.1 YbaN family protein -
  NST80_RS05520 (NST80_05520) vicX 1234840..1235652 (-) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  NST80_RS05525 (NST80_05525) vicK 1235658..1236998 (-) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NST80_RS05530 (NST80_05530) vicR 1236991..1237698 (-) 708 WP_002884978.1 response regulator YycF Regulator
  NST80_RS05535 (NST80_05535) - 1237983..1238750 (+) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  NST80_RS05540 (NST80_05540) - 1238760..1239593 (+) 834 WP_013990682.1 transporter substrate-binding domain-containing protein -
  NST80_RS05545 (NST80_05545) - 1239611..1240309 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  NST80_RS05550 (NST80_05550) - 1240321..1240971 (+) 651 WP_045769140.1 amino acid ABC transporter permease -
  NST80_RS05555 (NST80_05555) - 1241158..1241925 (+) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50945.21 Da        Isoelectric Point: 5.1606

>NTDB_id=986324 NST80_RS05525 WP_002885062.1 1235658..1236998(-) (vicK) [Streptococcus sp. FSL K6-1323]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=986324 NST80_RS05525 WP_002885062.1 1235658..1236998(-) (vicK) [Streptococcus sp. FSL K6-1323]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTTTCTTACATGAGTGATGGGGTTAT
TGCGACAAATCGTCGTGGTCAGATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTTTGGTTGCCGTTCTTCATGATGCTACTGAGCAGGAAAAAGAAGAGCGTGAACGCCGACTTTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGAGCTCTCGATGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCCAACTTGACGTTGAAATGACTAATTTCACAGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAGAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCTGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCGCAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCAAGAAGTCGTGCCCAGGGTGGAACTGGTCTA
GGCTTGTCTATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F3HCD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment