Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   R8623_RS04445 Genome accession   NZ_AP026928
Coordinates   872413..873063 (+) Length   216 a.a.
NCBI ID   WP_024477778.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 867413..878063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS04415 (PC0401_08580) - 867896..868111 (+) 216 WP_001232085.1 YozE family protein -
  R8623_RS04420 (PC0401_08590) - 868197..869165 (+) 969 WP_000658183.1 PhoH family protein -
  R8623_RS04425 - 869358..869859 (+) 502 Protein_873 GNAT family N-acetyltransferase -
  R8623_RS04430 - 869862..870187 (+) 326 Protein_874 TfoX/Sxy family protein -
  R8623_RS04435 ald 870488..871599 (-) 1112 Protein_875 alanine dehydrogenase -
  R8623_RS04440 (PC0401_08660) - 871776..872345 (+) 570 WP_000443774.1 GNAT family N-acetyltransferase -
  R8623_RS04445 (PC0401_08670) comEA/celA/cilE 872413..873063 (+) 651 WP_024477778.1 ComEA family DNA-binding protein Machinery gene
  R8623_RS04450 (PC0401_08680) comEC/celB 873047..875287 (+) 2241 WP_024477777.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  R8623_RS04455 (PC0401_08690) - 875466..875654 (+) 189 WP_001808514.1 hypothetical protein -
  R8623_RS04460 (PC0401_08700) - 875687..876274 (+) 588 WP_000939895.1 ATP-binding cassette domain-containing protein -
  R8623_RS04465 (PC0401_08710) - 876278..877462 (+) 1185 WP_000655960.1 ABC transporter permease -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23243.72 Da        Isoelectric Point: 6.0746

>NTDB_id=98579 R8623_RS04445 WP_024477778.1 872413..873063(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700406]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVKKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=98579 R8623_RS04445 WP_024477778.1 872413..873063(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700406]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAAGAAGGAAGAGAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAACTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae D39

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae R6

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

97.685

100

0.977
  comEA/celA/cilE Streptococcus mitis NCTC 12261

96.759

100

0.968
  comEA/celA/cilE Streptococcus mitis SK321

90.741

100

0.907
  comEA Lactococcus lactis subsp. cremoris KW2

41.333

100

0.431
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment