Detailed information NTG0098348

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: R8507_RS06035
• Genome accession: NZ_AP026925
• Coordinates: 1189733..1190581 (-)
• Length: 282 a.a.
• NCBI ID: WP_044812295.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700097
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1184733..1195581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8507_RS06015 (PC0094_11810)	-	1185087..1185446 (-)	360	WP_001237218.1	YbaN family protein	-
R8507_RS06020 (PC0094_11820)	topA	1185552..1187639 (-)	2088	WP_000179652.1	type I DNA topoisomerase	-
R8507_RS06025 (PC0094_11830)	-	1187806..1188849 (-)	1044	WP_001812957.1	TIGR00341 family protein	-
R8507_RS06030	-	1189427..1189549 (+)	123	WP_001814242.1	hypothetical protein	-
R8507_RS06035 (PC0094_11840)	dprA/cilB/dalA	1189733..1190581 (-)	849	WP_044812295.1	DNA-processing protein DprA	Machinery gene
R8507_RS06040 (PC0094_11850)	-	1190677..1191366 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
R8507_RS06045 (PC0094_11860)	-	1191378..1192256 (-)	879	WP_000837609.1	DMT family transporter	-
R8507_RS06050 (PC0094_11870)	licA	1192246..1193115 (-)	870	WP_000411210.1	choline kinase LicA	-
R8507_RS06055 (PC0094_11880)	-	1193132..1194154 (-)	1023	WP_000609894.1	ribitol-5-phosphate dehydrogenase	-
R8507_RS06060 (PC0094_11890)	-	1194159..1194866 (-)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31092.75 Da
• Isoelectric Point: 5.4047

>NTDB_id=98348 R8507_RS06035 WP_044812295.1 1189733..1190581(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PZ900700097]
MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=98348 R8507_RS06035 WP_044812295.1 1189733..1190581(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PZ900700097]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAAGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.809	100	0.379
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362