Detailed information NTG0098333

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R8507_RS02450
• Genome accession: NZ_AP026925
• Coordinates: 473284..473871 (-)
• Length: 195 a.a.
• NCBI ID: WP_317643599.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700097
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 468284..478871

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8507_RS02430 (PC0094_04780)	-	468746..470086 (+)	1341	WP_317643596.1	sensor histidine kinase	-
R8507_RS02435 (PC0094_04790)	blpC	470157..470285 (-)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
R8507_RS02440 (PC0094_04800)	-	470342..471703 (-)	1362	WP_001069060.1	bacteriocin secretion accessory protein	-
R8507_RS02445 (PC0094_04810)	comA/nlmT	471792..473390 (-)	1599	WP_317643771.1	peptide cleavage/export ABC transporter	Regulator
R8507_RS02450 (PC0094_04820)	comA/nlmT	473284..473871 (-)	588	WP_317643599.1	cysteine peptidase family C39 domain-containing protein	Regulator
R8507_RS02455 (PC0094_04830)	blpI	474153..474350 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
R8507_RS02460 (PC0094_04840)	blpJ	474817..475086 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
R8507_RS02465 (PC0094_04850)	blpK	475155..475403 (+)	249	WP_000379965.1	bacteriocin-like peptide BlpK	-
R8507_RS02470 (PC0094_04860)	cipB	475647..475796 (+)	150	WP_001809846.1	bacteriocin-like peptide BlpO	Regulator
R8507_RS10830	-	475832..475897 (+)	66	Protein_487	ComC/BlpC family peptide pheromone/bacteriocin	-
R8507_RS02475	-	475900..476019 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
R8507_RS02480 (PC0094_04880)	-	476539..476871 (+)	333	WP_224757293.1	immunity protein	-
R8507_RS02485 (PC0094_04900)	-	477500..477883 (+)	384	WP_016398494.1	hypothetical protein	-
R8507_RS02490 (PC0094_04910)	-	477935..478624 (+)	690	WP_000760523.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22316.79 Da
• Isoelectric Point: 9.5013

>NTDB_id=98333 R8507_RS02450 WP_317643599.1 473284..473871(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700097]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMCFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=98333 R8507_RS02450 WP_317643599.1 473284..473871(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700097]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGTGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.341	93.333	0.554
comA	Streptococcus mitis NCTC 12261	54.348	94.359	0.513
comA	Streptococcus mitis SK321	53.804	94.359	0.508
comA	Streptococcus pneumoniae TIGR4	53.261	94.359	0.503
comA	Streptococcus pneumoniae Rx1	53.261	94.359	0.503
comA	Streptococcus pneumoniae D39	53.261	94.359	0.503
comA	Streptococcus pneumoniae R6	53.261	94.359	0.503
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497