Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8507_RS02445 Genome accession   NZ_AP026925
Coordinates   471792..473390 (-) Length   532 a.a.
NCBI ID   WP_317643771.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700097     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 466792..478390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8507_RS02415 (PC0094_04750) - 467048..467377 (-) 330 WP_000132575.1 hypothetical protein -
  R8507_RS02420 (PC0094_04760) - 467653..467991 (+) 339 WP_000682122.1 LytTR family DNA-binding domain-containing protein -
  R8507_RS02425 (PC0094_04770) comE/blpR 467996..468733 (+) 738 WP_001219126.1 response regulator transcription factor Regulator
  R8507_RS02430 (PC0094_04780) - 468746..470086 (+) 1341 WP_317643596.1 sensor histidine kinase -
  R8507_RS02435 (PC0094_04790) blpC 470157..470285 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  R8507_RS02440 (PC0094_04800) - 470342..471703 (-) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  R8507_RS02445 (PC0094_04810) comA/nlmT 471792..473390 (-) 1599 WP_317643771.1 peptide cleavage/export ABC transporter Regulator
  R8507_RS02450 (PC0094_04820) comA/nlmT 473284..473871 (-) 588 WP_317643599.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8507_RS02455 (PC0094_04830) blpI 474153..474350 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8507_RS02460 (PC0094_04840) blpJ 474817..475086 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R8507_RS02465 (PC0094_04850) blpK 475155..475403 (+) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  R8507_RS02470 (PC0094_04860) cipB 475647..475796 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R8507_RS10830 - 475832..475897 (+) 66 Protein_487 ComC/BlpC family peptide pheromone/bacteriocin -
  R8507_RS02475 - 475900..476019 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R8507_RS02480 (PC0094_04880) - 476539..476871 (+) 333 WP_224757293.1 immunity protein -
  R8507_RS02485 (PC0094_04900) - 477500..477883 (+) 384 WP_016398494.1 hypothetical protein -

Sequence

Protein


Download         Length: 532 a.a.        Molecular weight: 59940.83 Da        Isoelectric Point: 6.5970

>NTDB_id=98332 R8507_RS02445 WP_317643771.1 471792..473390(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700097]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LILNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLD

Nucleotide


Download         Length: 1599 bp        

>NTDB_id=98332 R8507_RS02445 WP_317643771.1 471792..473390(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700097]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAATTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGACATATTTCTATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)

ABC transporter (ABC_tran)

(341-490)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.684

100

0.737
  comA Streptococcus mitis NCTC 12261

68.105

100

0.682
  comA Streptococcus pneumoniae Rx1

67.73

100

0.679
  comA Streptococcus pneumoniae D39

67.73

100

0.679
  comA Streptococcus pneumoniae R6

67.73

100

0.679
  comA Streptococcus mitis SK321

67.542

100

0.677
  comA Streptococcus pneumoniae TIGR4

67.355

100

0.675
  comA Streptococcus gordonii str. Challis substr. CH1

67.228

100

0.675

Multiple sequence alignment