Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8635_RS08685 Genome accession   NZ_AP026924
Coordinates   1677817..1679460 (+) Length   547 a.a.
NCBI ID   WP_317657564.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1672817..1684460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS08635 (PC0062_17150) blpN 1673160..1673363 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  R8635_RS08640 (PC0062_17160) blpM 1673379..1673633 (-) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  R8635_RS08645 - 1673783..1674586 (-) 804 Protein_1718 IS5 family transposase -
  R8635_RS08650 (PC0062_17190) - 1674789..1675193 (-) 405 WP_000846944.1 hypothetical protein -
  R8635_RS08655 (PC0062_17200) - 1675190..1675354 (-) 165 WP_000727118.1 hypothetical protein -
  R8635_RS08660 - 1675651..1675770 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  R8635_RS08665 (PC0062_17210) blpU 1675773..1676003 (-) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  R8635_RS08670 (PC0062_17220) blpJ 1676072..1676341 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R8635_RS08675 (PC0062_17240) blpI 1676808..1677005 (-) 198 WP_001093261.1 bacteriocin-like peptide BlpI -
  R8635_RS08680 (PC0062_17250) comA/nlmT 1677303..1677890 (+) 588 WP_317657537.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8635_RS08685 (PC0062_17260) comA/nlmT 1677817..1679460 (+) 1644 WP_317657564.1 peptide cleavage/export ABC transporter Regulator
  R8635_RS08690 (PC0062_17280) - 1679471..1680832 (+) 1362 Protein_1727 bacteriocin secretion accessory protein -
  R8635_RS08695 (PC0062_17290) blpC 1680889..1681017 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  R8635_RS08700 (PC0062_17300) - 1681088..1682428 (-) 1341 WP_001017646.1 sensor histidine kinase -
  R8635_RS08705 (PC0062_17310) comE/blpR 1682442..1683179 (-) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  R8635_RS08710 (PC0062_17320) - 1683184..1683522 (-) 339 WP_000682120.1 LytTR family DNA-binding domain-containing protein -
  R8635_RS08715 (PC0062_17330) - 1683799..1684128 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61673.60 Da        Isoelectric Point: 6.5101

>NTDB_id=98275 R8635_RS08685 WP_317657564.1 1677817..1679460(+) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700063]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=98275 R8635_RS08685 WP_317657564.1 1677817..1679460(+) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700063]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAGTACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTGGCACAAA
ACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTTGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAAAGCTTATGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.711

99.817

0.726
  comA Streptococcus pneumoniae Rx1

67.459

100

0.675
  comA Streptococcus pneumoniae D39

67.459

100

0.675
  comA Streptococcus pneumoniae R6

67.459

100

0.675
  comA Streptococcus mitis NCTC 12261

67.459

100

0.675
  comA Streptococcus pneumoniae TIGR4

67.093

100

0.671
  comA Streptococcus gordonii str. Challis substr. CH1

66.788

100

0.669
  comA Streptococcus mitis SK321

66.91

100

0.669

Multiple sequence alignment