Detailed information NTG0098274

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R8635_RS08680
• Genome accession: NZ_AP026924
• Coordinates: 1677303..1677890 (+)
• Length: 195 a.a.
• NCBI ID: WP_317657537.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700063
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1672303..1682890

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8635_RS08625	-	1672544..1672663 (-)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
R8635_RS08630 (PC0062_17140)	cipB	1672767..1672916 (-)	150	WP_001820573.1	bacteriocin-like peptide BlpO	Regulator
R8635_RS08635 (PC0062_17150)	blpN	1673160..1673363 (-)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
R8635_RS08640 (PC0062_17160)	blpM	1673379..1673633 (-)	255	WP_000379877.1	two-peptide bacteriocin subunit BlpM	-
R8635_RS08645	-	1673783..1674586 (-)	804	Protein_1718	IS5 family transposase	-
R8635_RS08650 (PC0062_17190)	-	1674789..1675193 (-)	405	WP_000846944.1	hypothetical protein	-
R8635_RS08655 (PC0062_17200)	-	1675190..1675354 (-)	165	WP_000727118.1	hypothetical protein	-
R8635_RS08660	-	1675651..1675770 (-)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
R8635_RS08665 (PC0062_17210)	blpU	1675773..1676003 (-)	231	WP_000379967.1	bacteriocin-like peptide BlpU	-
R8635_RS08670 (PC0062_17220)	blpJ	1676072..1676341 (-)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
R8635_RS08675 (PC0062_17240)	blpI	1676808..1677005 (-)	198	WP_001093261.1	bacteriocin-like peptide BlpI	-
R8635_RS08680 (PC0062_17250)	comA/nlmT	1677303..1677890 (+)	588	WP_317657537.1	cysteine peptidase family C39 domain-containing protein	Regulator
R8635_RS08685 (PC0062_17260)	comA/nlmT	1677817..1679460 (+)	1644	WP_317657564.1	peptide cleavage/export ABC transporter	Regulator
R8635_RS08690 (PC0062_17280)	-	1679471..1680832 (+)	1362	Protein_1727	bacteriocin secretion accessory protein	-
R8635_RS08695 (PC0062_17290)	blpC	1680889..1681017 (+)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
R8635_RS08700 (PC0062_17300)	-	1681088..1682428 (-)	1341	WP_001017646.1	sensor histidine kinase	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22303.78 Da
• Isoelectric Point: 9.8209

>NTDB_id=98274 R8635_RS08680 WP_317657537.1 1677303..1677890(+) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700063]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKFQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYKWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=98274 R8635_RS08680 WP_317657537.1 1677303..1677890(+) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700063]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAATTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATAAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	58.791	93.333	0.549
comA	Streptococcus mitis NCTC 12261	53.804	94.359	0.508
comA	Streptococcus mitis SK321	53.261	94.359	0.503
comA	Streptococcus pneumoniae TIGR4	52.717	94.359	0.497
comA	Streptococcus pneumoniae Rx1	52.717	94.359	0.497
comA	Streptococcus pneumoniae D39	52.717	94.359	0.497
comA	Streptococcus pneumoniae R6	52.717	94.359	0.497
comA	Streptococcus gordonii str. Challis substr. CH1	51.63	94.359	0.487