Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   R8635_RS07700 Genome accession   NZ_AP026924
Coordinates   1479901..1480491 (-) Length   196 a.a.
NCBI ID   WP_000613477.1    Uniprot ID   A0A064BX72
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1474901..1485491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS07675 (PC0062_15240) - 1475452..1476216 (-) 765 WP_001186003.1 ABC transporter ATP-binding protein -
  R8635_RS07680 (PC0062_15250) - 1476216..1477172 (-) 957 WP_000662293.1 branched-chain amino acid ABC transporter permease -
  R8635_RS07685 (PC0062_15260) - 1477176..1478045 (-) 870 WP_081541426.1 branched-chain amino acid ABC transporter permease -
  R8635_RS07690 (PC0062_15270) - 1478313..1479473 (-) 1161 WP_000726142.1 ABC transporter substrate-binding protein -
  R8635_RS07695 (PC0062_15280) - 1479574..1479822 (-) 249 WP_000462126.1 YlbG family protein -
  R8635_RS07700 (PC0062_15290) clpP 1479901..1480491 (-) 591 WP_000613477.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  R8635_RS07705 (PC0062_15300) upp 1480665..1481294 (-) 630 WP_050205350.1 uracil phosphoribosyltransferase -
  R8635_RS07710 (PC0062_15310) - 1481383..1481850 (-) 468 WP_000136976.1 cytidine/deoxycytidylate deaminase family protein -
  R8635_RS07715 (PC0062_15320) - 1481869..1482426 (-) 558 WP_000004139.1 TetR/AcrR family transcriptional regulator -
  R8635_RS07720 (PC0062_15330) - 1482551..1483396 (+) 846 WP_000219939.1 DegV family protein -
  R8635_RS07725 (PC0062_15340) - 1483455..1484627 (+) 1173 WP_000680058.1 NAD(P)/FAD-dependent oxidoreductase -
  R8635_RS07730 (PC0062_15350) - 1484678..1484869 (+) 192 Protein_1535 DUF1697 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21358.36 Da        Isoelectric Point: 4.4910

>NTDB_id=98271 R8635_RS07700 WP_000613477.1 1479901..1480491(-) (clpP) [Streptococcus pneumoniae strain PZ900700063]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=98271 R8635_RS07700 WP_000613477.1 1479901..1480491(-) (clpP) [Streptococcus pneumoniae strain PZ900700063]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATCGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064BX72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

100

100

1
  clpP Streptococcus pneumoniae D39

100

100

1
  clpP Streptococcus pneumoniae R6

100

100

1
  clpP Streptococcus pneumoniae TIGR4

100

100

1
  clpP Streptococcus thermophilus LMG 18311

92.821

99.49

0.923
  clpP Streptococcus thermophilus LMD-9

92.821

99.49

0.923
  clpP Streptococcus pyogenes JRS4

90.769

99.49

0.903
  clpP Streptococcus pyogenes MGAS315

90.769

99.49

0.903
  clpP Streptococcus mutans UA159

85.714

100

0.857
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

85.128

99.49

0.847
  clpP Lactococcus lactis subsp. cremoris KW2

84.615

99.49

0.842
  clpP Bacillus subtilis subsp. subtilis str. 168

58.854

97.959

0.577
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.031

98.469

0.571

Multiple sequence alignment