Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8586_RS02565 Genome accession   NZ_AP026922
Coordinates   497524..499014 (-) Length   496 a.a.
NCBI ID   WP_001818755.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 492524..504014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS02535 (PC0038_04970) - 492856..493185 (-) 330 WP_000132572.1 hypothetical protein -
  R8586_RS02540 (PC0038_04980) - 493462..493800 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  R8586_RS02545 (PC0038_04990) comE/blpR 493805..494542 (+) 738 WP_001219141.1 response regulator transcription factor Regulator
  R8586_RS02550 (PC0038_05000) - 494556..495896 (+) 1341 WP_001099892.1 sensor histidine kinase -
  R8586_RS02555 (PC0038_05010) blpC 495940..496095 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  R8586_RS02560 (PC0038_05020) - 496152..497513 (-) 1362 WP_001069071.1 bacteriocin secretion accessory protein -
  R8586_RS02565 (PC0038_05030) comA/nlmT 497524..499014 (-) 1491 WP_001818755.1 peptide cleavage/export ABC transporter Regulator
  R8586_RS02570 (PC0038_05040) comA/nlmT 499106..499693 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8586_RS02575 (PC0038_05050) blpI 499975..500172 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8586_RS02580 (PC0038_05070) blpJ 500639..500908 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R8586_RS02585 (PC0038_05080) blpU 500977..501207 (+) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  R8586_RS02590 - 501210..501329 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R8586_RS02595 (PC0038_05100) - 502115..502499 (+) 385 Protein_510 immunity protein -
  R8586_RS02600 (PC0038_05110) - 502551..503240 (+) 690 WP_000760515.1 CPBP family intramembrane glutamic endopeptidase -
  R8586_RS02605 (PC0038_05120) blpZ 503282..503530 (+) 249 WP_000276500.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56059.95 Da        Isoelectric Point: 6.6428

>NTDB_id=98094 R8586_RS02565 WP_001818755.1 497524..499014(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700038]
MSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLL
AQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKS
FKLSKYSILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLPSAKVANNRLNEV
YLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHI
SINHQDIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGL
SGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSH
QELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=98094 R8586_RS02565 WP_001818755.1 497524..499014(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700038]
ATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCA
TATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTA
TTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTG
GCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACC
TTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTG
AAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCC
TTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATG
GTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTA
CAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCCATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTC
TATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGA
CCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCC
TAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATT
TCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTA
TATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTT
GTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTA
TCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGACGAAGCTAC
TAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAG
CCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCAC
CAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(279-428)

ABC transporter transmembrane region (ABC_membrane)

(2-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.333

99.798

0.732
  comA Streptococcus gordonii str. Challis substr. CH1

67.002

100

0.671
  comA Streptococcus mitis NCTC 12261

67.137

100

0.671
  comA Streptococcus pneumoniae Rx1

66.734

100

0.667
  comA Streptococcus pneumoniae D39

66.734

100

0.667
  comA Streptococcus pneumoniae R6

66.734

100

0.667
  comA Streptococcus mitis SK321

66.532

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.532

100

0.665

Multiple sequence alignment