Detailed information NTG0097859

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R8613_RS02715
• Genome accession: NZ_AP026919
• Coordinates: 512235..514388 (-)
• Length: 717 a.a.
• NCBI ID: WP_024478410.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700012
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 507235..519388

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8613_RS02685 (PC0012_05120)	-	507568..507897 (-)	330	WP_000132575.1	hypothetical protein	-
R8613_RS02690 (PC0012_05130)	-	508173..508511 (+)	339	WP_000876675.1	LytTR family DNA-binding domain-containing protein	-
R8613_RS02695 (PC0012_05140)	comE/blpR	508516..509253 (+)	738	WP_001219121.1	response regulator transcription factor	Regulator
R8613_RS02700 (PC0012_05150)	-	509267..510607 (+)	1341	WP_001099893.1	sensor histidine kinase	-
R8613_RS02705 (PC0012_05160)	blpC	510651..510806 (-)	156	WP_000358811.1	quorum-sensing system pheromone BlpC	-
R8613_RS02710 (PC0012_05170)	-	510863..512224 (-)	1362	WP_001865175.1	bacteriocin secretion accessory protein	-
R8613_RS02715 (PC0012_05180)	comA/nlmT	512235..514388 (-)	2154	WP_024478410.1	peptide cleavage/export ABC transporter BlpA	Regulator
R8613_RS02720 (PC0012_05190)	blpU	514669..514899 (+)	231	WP_001093268.1	bacteriocin-like peptide BlpU	-
R8613_RS02725	-	514902..515021 (+)	120	WP_001829206.1	PncF family bacteriocin immunity protein	-
R8613_RS02730 (PC0012_05210)	-	515490..515861 (+)	372	WP_033705507.1	hypothetical protein	-
R8613_RS02735	-	516214..516407 (+)	194	Protein_539	hypothetical protein	-
R8613_RS02740 (PC0012_05230)	-	516490..516873 (+)	384	WP_000877381.1	hypothetical protein	-
R8613_RS02745 (PC0012_05240)	-	516925..517614 (+)	690	WP_000760515.1	CPBP family intramembrane glutamic endopeptidase	-
R8613_RS02750 (PC0012_05250)	blpZ	517656..517889 (+)	234	WP_001849865.1	immunity protein BlpZ	-
R8613_RS02755	-	518040..518651 (+)	612	WP_088783499.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80827.85 Da
• Isoelectric Point: 7.6798

>NTDB_id=97859 R8613_RS02715 WP_024478410.1 512235..514388(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700012]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=97859 R8613_RS02715 WP_024478410.1 512235..514388(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700012]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGGCCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTA
CTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGTTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.168	99.721	0.72
comA	Streptococcus mitis NCTC 12261	66.76	99.442	0.664
comA	Streptococcus pneumoniae Rx1	66.199	99.442	0.658
comA	Streptococcus pneumoniae R6	66.199	99.442	0.658
comA	Streptococcus pneumoniae D39	66.199	99.442	0.658
comA	Streptococcus mitis SK321	66.199	99.442	0.658
comA	Streptococcus gordonii str. Challis substr. CH1	65.46	100	0.656
comA	Streptococcus pneumoniae TIGR4	65.919	99.442	0.656