Detailed information NTG0097704

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R8563_RS02480
• Genome accession: NZ_AP026917
• Coordinates: 485464..487617 (-)
• Length: 717 a.a.
• NCBI ID: WP_054383088.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700007
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 480464..492617

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8563_RS02450 (PC0007_04730)	-	480796..481125 (-)	330	WP_000132572.1	hypothetical protein	-
R8563_RS02455 (PC0007_04740)	-	481401..481739 (+)	339	WP_000682121.1	LytTR family DNA-binding domain-containing protein	-
R8563_RS02460 (PC0007_04750)	comE/blpR	481744..482481 (+)	738	WP_001219126.1	response regulator transcription factor	Regulator
R8563_RS02465 (PC0007_04760)	-	482495..483835 (+)	1341	WP_317636774.1	sensor histidine kinase	-
R8563_RS02470 (PC0007_04770)	blpC	483880..484035 (-)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
R8563_RS02475 (PC0007_04780)	-	484092..485453 (-)	1362	WP_001069067.1	bacteriocin secretion accessory protein	-
R8563_RS02480 (PC0007_04790)	comA/nlmT	485464..487617 (-)	2154	WP_054383088.1	peptide cleavage/export ABC transporter BlpA	Regulator
R8563_RS02485 (PC0007_04800)	blpI	487898..488095 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
R8563_RS02490 (PC0007_04820)	blpJ	488561..488830 (+)	270	WP_001093249.1	bacteriocin-like peptide BlpJ	-
R8563_RS02500 (PC0007_04830)	-	488899..489128 (+)	230	Protein_491	Blp family class II bacteriocin	-
R8563_RS02505	-	489131..489250 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
R8563_RS02510 (PC0007_04840)	-	489547..489711 (+)	165	WP_000727118.1	hypothetical protein	-
R8563_RS02515 (PC0007_04850)	-	489708..490112 (+)	405	WP_000846943.1	hypothetical protein	-
R8563_RS02520	-	490315..491119 (+)	805	WP_151394153.1	IS5 family transposase	-
R8563_RS02525 (PC0007_04880)	blpM	491269..491523 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
R8563_RS02530 (PC0007_04890)	blpN	491539..491742 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
R8563_RS02535 (PC0007_04900)	cipB	491986..492135 (+)	150	WP_001818346.1	bacteriocin-like peptide BlpO	Regulator
R8563_RS10835	-	492171..492236 (+)	66	Protein_499	ComC/BlpC family peptide pheromone/bacteriocin	-
R8563_RS02540	-	492239..492358 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80817.81 Da
• Isoelectric Point: 7.6796

>NTDB_id=97704 R8563_RS02480 WP_054383088.1 485464..487617(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700007]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLITYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=97704 R8563_RS02480 WP_054383088.1 485464..487617(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700007]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGGCCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGGTTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTACTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTAGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTCCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACAAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAG
TCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.748	99.721	0.715
comA	Streptococcus mitis NCTC 12261	66.059	99.442	0.657
comA	Streptococcus gordonii str. Challis substr. CH1	65.042	100	0.651
comA	Streptococcus pneumoniae Rx1	65.498	99.442	0.651
comA	Streptococcus pneumoniae D39	65.498	99.442	0.651
comA	Streptococcus pneumoniae R6	65.498	99.442	0.651
comA	Streptococcus mitis SK321	65.498	99.442	0.651
comA	Streptococcus pneumoniae TIGR4	65.217	99.442	0.649