Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8522_RS02555 Genome accession   NZ_AP026916
Coordinates   497745..499421 (-) Length   558 a.a.
NCBI ID   WP_196302068.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 492745..504421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS02525 (PC0006_05130) - 493078..493407 (-) 330 WP_000132575.1 hypothetical protein -
  R8522_RS02530 (PC0006_05140) - 493684..494022 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  R8522_RS02535 (PC0006_05150) comE/blpR 494027..494764 (+) 738 WP_001219122.1 LytTR family DNA-binding domain-containing protein Regulator
  R8522_RS02540 (PC0006_05160) - 494777..496117 (+) 1341 WP_050123659.1 sensor histidine kinase -
  R8522_RS02545 (PC0006_05170) blpC 496188..496316 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  R8522_RS02550 (PC0006_05180) - 496373..497734 (-) 1362 WP_050122537.1 bacteriocin secretion accessory protein -
  R8522_RS02555 (PC0006_05190) comA/nlmT 497745..499421 (-) 1677 WP_196302068.1 peptide cleavage/export ABC transporter Regulator
  R8522_RS02560 (PC0006_05200) comA/nlmT 499315..499902 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8522_RS02565 (PC0006_05210) blpI 500183..500380 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8522_RS02570 (PC0006_05230) blpJ 500847..501116 (+) 270 WP_050122544.1 bacteriocin-like peptide BlpJ -
  R8522_RS02575 (PC0006_05240) - 501185..501469 (+) 285 WP_050122547.1 Blp family class II bacteriocin -
  R8522_RS02580 (PC0006_05250) cipB 501713..501862 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R8522_RS02585 - 501966..502085 (+) 120 WP_001833623.1 PncF family bacteriocin immunity protein -
  R8522_RS02590 (PC0006_05270) - 502567..502925 (+) 359 Protein_511 immunity protein -
  R8522_RS02595 - 503086..504055 (+) 970 Protein_512 thioredoxin domain-containing protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62935.24 Da        Isoelectric Point: 6.6431

>NTDB_id=97627 R8522_RS02555 WP_196302068.1 497745..499421(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700006]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHIFINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAEQTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=97627 R8522_RS02555 WP_196302068.1 497745..499421(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700006]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAAAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTTCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACAAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)

ABC transporter (ABC_tran)

(341-490)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.711

99.821

0.726
  comA Streptococcus pneumoniae Rx1

66.846

100

0.668
  comA Streptococcus pneumoniae D39

66.846

100

0.668
  comA Streptococcus pneumoniae R6

66.846

100

0.668
  comA Streptococcus mitis NCTC 12261

66.846

100

0.668
  comA Streptococcus gordonii str. Challis substr. CH1

66.369

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.487

100

0.665
  comA Streptococcus mitis SK321

66.308

100

0.663

Multiple sequence alignment