Detailed information NTG0972968

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: AAAF57_RS05495
• Genome accession: NZ_CP150847
• Coordinates: 1224212..1224919 (-)
• Length: 235 a.a.
• NCBI ID: WP_002884978.1
• Uniprot ID: A0AB33ZBK5
• Organism: Streptococcus salivarius strain KSS5
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1219212..1229919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAAF57_RS05470 (AAAF57_05515)	yidA	1219566..1220375 (+)	810	WP_002890845.1	sugar-phosphatase	-
AAAF57_RS05475 (AAAF57_05520)	-	1220377..1221591 (+)	1215	WP_073687783.1	aminoacyltransferase	-
AAAF57_RS05480 (AAAF57_05525)	-	1221643..1222002 (-)	360	WP_037611660.1	YbaN family protein	-
AAAF57_RS05485 (AAAF57_05530)	vicX	1222061..1222870 (-)	810	WP_126405093.1	MBL fold metallo-hydrolase	Regulator
AAAF57_RS05490 (AAAF57_05535)	vicK	1222876..1224219 (-)	1344	WP_410536163.1	cell wall metabolism sensor histidine kinase VicK	Regulator
AAAF57_RS05495 (AAAF57_05540)	vicR	1224212..1224919 (-)	708	WP_002884978.1	response regulator YycF	Regulator
AAAF57_RS05500 (AAAF57_05545)	-	1225204..1225971 (+)	768	WP_002885036.1	amino acid ABC transporter ATP-binding protein	-
AAAF57_RS05505 (AAAF57_05550)	-	1226072..1226815 (+)	744	WP_410536165.1	transporter substrate-binding domain-containing protein	-
AAAF57_RS05510 (AAAF57_05555)	-	1226833..1227531 (+)	699	WP_002886251.1	amino acid ABC transporter permease	-
AAAF57_RS05515 (AAAF57_05560)	-	1227543..1228193 (+)	651	WP_002886253.1	amino acid ABC transporter permease	-
AAAF57_RS05520 (AAAF57_05565)	-	1228381..1229148 (+)	768	WP_037604317.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27045.90 Da
• Isoelectric Point: 4.8387

>NTDB_id=972968 AAAF57_RS05495 WP_002884978.1 1224212..1224919(-) (vicR) [Streptococcus salivarius strain KSS5]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=972968 AAAF57_RS05495 WP_002884978.1 1224212..1224919(-) (vicR) [Streptococcus salivarius strain KSS5]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.559	100	0.387