Detailed information NTG0971448

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: ACJX2R_RS34600
• Genome accession: NZ_CP178360
• Coordinates: 8129864..8130520 (+)
• Length: 218 a.a.
• NCBI ID: WP_413103304.1
• Uniprot ID: -
• Organism: Streptomyces sp. Inha503
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 8124864..8135520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJX2R_RS34580 (ACJX2R_34655)	mce	8126077..8126529 (-)	453	WP_262701591.1	methylmalonyl-CoA epimerase	-
ACJX2R_RS34585 (ACJX2R_34660)	-	8126686..8127864 (+)	1179	WP_413106012.1	acetyl-CoA C-acetyltransferase	-
ACJX2R_RS34590 (ACJX2R_34665)	meaB	8127957..8128916 (+)	960	WP_413103302.1	methylmalonyl Co-A mutase-associated GTPase MeaB	-
ACJX2R_RS34595 (ACJX2R_34670)	-	8129188..8129751 (-)	564	WP_413103303.1	PepSY domain-containing protein	-
ACJX2R_RS34600 (ACJX2R_34675)	ciaR	8129864..8130520 (+)	657	WP_413103304.1	response regulator transcription factor	Regulator
ACJX2R_RS34605 (ACJX2R_34680)	-	8130513..8131919 (+)	1407	WP_413103305.1	ATP-binding protein	-
ACJX2R_RS34610 (ACJX2R_34685)	-	8131916..8132392 (-)	477	WP_020868377.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACJX2R_RS34615 (ACJX2R_34690)	-	8132487..8133167 (-)	681	WP_262701596.1	AIM24 family protein	-
ACJX2R_RS34620 (ACJX2R_34695)	-	8133164..8133814 (-)	651	WP_413103306.1	AIM24 family protein	-
ACJX2R_RS34625 (ACJX2R_34700)	-	8133814..8134452 (-)	639	WP_413103307.1	AIM24 family protein	-
ACJX2R_RS34630 (ACJX2R_34705)	-	8134616..8134960 (+)	345	WP_020868373.1	DUF3817 domain-containing protein	-
ACJX2R_RS34635 (ACJX2R_34710)	-	8134957..8135250 (+)	294	WP_020868372.1	MTH1187 family thiamine-binding protein	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 23780.23 Da
• Isoelectric Point: 5.8075

>NTDB_id=971448 ACJX2R_RS34600 WP_413103304.1 8129864..8130520(+) (ciaR) [Streptomyces sp. Inha503]
MRLLIVEDERRLALSLAKGLRAEGFAVDVAHDGQEGLHRAQEGVYDLVVLDIMLPGLNGYRVCGALRAAGNEVPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLVARVRALLRRRGPGASPVVRVGPLTVDRGARRVERDGREAPLTAKEFSVLEQ
LATRAGDVVSKAEILEHVWDFAYDGDPNIVEVYVSALRRKLGAGLIETVRGAGYRLRA

Nucleotide

• Length: 657 bp

>NTDB_id=971448 ACJX2R_RS34600 WP_413103304.1 8129864..8130520(+) (ciaR) [Streptomyces sp. Inha503]
ATGCGTTTGCTGATTGTGGAGGACGAGCGGCGGCTGGCCCTGTCGCTGGCCAAGGGGCTGCGGGCGGAGGGGTTCGCCGT
CGATGTGGCGCACGATGGCCAGGAGGGGCTGCACCGTGCGCAGGAGGGGGTGTACGACCTCGTCGTCCTCGACATCATGC
TGCCGGGGCTGAACGGCTACCGCGTATGCGGGGCGCTCCGGGCGGCCGGGAACGAGGTGCCGATCCTGATGCTCACCGCC
AAGGACGGCGAGTACGACGAGGCGGAGGGGCTCGACACCGGGGCCGACGACTATCTGACCAAGCCGTTCTCGTATGTGGT
GCTGGTGGCGCGGGTGCGGGCGCTGCTGCGGCGGCGCGGCCCGGGGGCCTCGCCCGTGGTGCGGGTGGGGCCGCTCACCG
TGGACCGGGGCGCGCGCCGGGTGGAGCGGGACGGCCGGGAGGCGCCGCTGACCGCCAAGGAGTTCTCCGTGCTGGAGCAA
TTGGCGACGCGGGCGGGGGACGTGGTTTCCAAGGCGGAGATCCTGGAGCATGTGTGGGACTTCGCCTACGACGGCGACCC
CAACATCGTCGAGGTGTATGTGAGCGCCCTGCGCCGCAAGTTGGGCGCGGGGCTCATCGAGACCGTACGGGGAGCGGGGT
ACCGGCTCCGTGCGTAA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-216)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	40.807	100	0.417
vicR	Streptococcus mutans UA159	38.793	100	0.413
covR	Streptococcus salivarius strain HSISS4	38.767	100	0.404
micA	Streptococcus pneumoniae Cp1015	38.261	100	0.404
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.839	100	0.399
ciaR	Streptococcus pneumoniae Rx1	37.838	100	0.385
ciaR	Streptococcus pneumoniae D39	37.838	100	0.385
ciaR	Streptococcus pneumoniae R6	37.838	100	0.385
ciaR	Streptococcus pneumoniae TIGR4	37.838	100	0.385