Detailed information NTG0969482

Bioinformatically predicted

Overview

• Name: comR/comR1
• Type: Regulator
• Locus tag: ACJVC4_RS06480
• Genome accession: NZ_CP177179
• Coordinates: 1323865..1324770 (+)
• Length: 301 a.a.
• NCBI ID: WP_002891217.1
• Uniprot ID: J7TIP3
• Organism: Streptococcus salivarius strain MRD-NRLLH
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1318865..1329770

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJVC4_RS06455	-	1319351..1320271 (-)	921	WP_002891211.1	multidrug resistance efflux transporter family protein	-
ACJVC4_RS06460	-	1320426..1320947 (-)	522	WP_224111181.1	RDD family protein	-
ACJVC4_RS06465	comR	1321165..1322073 (+)	909	WP_002891213.1	helix-turn-helix domain-containing protein	Regulator
ACJVC4_RS06470	-	1322159..1322995 (+)	837	WP_002891214.1	ABC transporter ATP-binding protein	-
ACJVC4_RS06475	-	1322988..1323707 (+)	720	WP_002891215.1	ABC transporter permease	-
ACJVC4_RS06480	comR/comR1	1323865..1324770 (+)	906	WP_002891217.1	helix-turn-helix domain-containing protein	Regulator
ACJVC4_RS06485	-	1324883..1325770 (-)	888	WP_002891218.1	hypothetical protein	-
ACJVC4_RS06490	-	1326142..1326603 (-)	462	WP_037597934.1	GNAT family N-acetyltransferase	-
ACJVC4_RS06495	-	1326642..1327427 (-)	786	WP_002891220.1	ABC transporter permease	-
ACJVC4_RS06500	-	1327429..1328247 (-)	819	WP_037597935.1	ABC transporter permease	-
ACJVC4_RS06505	-	1328249..1329241 (-)	993	WP_002891222.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35586.98 Da
• Isoelectric Point: 4.5336

>NTDB_id=969482 ACJVC4_RS06480 WP_002891217.1 1323865..1324770(+) (comR/comR1) [Streptococcus salivarius strain MRD-NRLLH]
MSDDIKIEIGKRIREERERIGLTREQVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLGVSLNYLLGETKLDIPEDY
YKAKYKLMKSPVYGDPERIKKKLKDIEELYDNYIDILPEDELFAIDIIERTLNFMVMEEDSLIESVFEDYLTQALKKEAY
SLNDLLLISYYALRCQDYDYDKGIIDEFRRKLIKQELQGEELFNIELMGALTSIAGIYVMHHDYKDMKSVVDKLYEIMHS
CMQHSYQPGIIVFEAKYYLFYENNREKATELYHTATLLAEAFGDQVFIKNLKMEIEKDLNI

Nucleotide

• Length: 906 bp

>NTDB_id=969482 ACJVC4_RS06480 WP_002891217.1 1323865..1324770(+) (comR/comR1) [Streptococcus salivarius strain MRD-NRLLH]
ATGTCTGATGATATTAAAATCGAGATTGGAAAAAGAATTCGTGAAGAACGTGAACGAATAGGTTTAACACGTGAGCAGGT
TTGTGACACAGAAGAAGAATTAACCGTCAAACAACTGATGAGAATTGAGCTCGGTCGCTCATTACCAACTATTGTCAAAC
TGCAGTATATCAGTGATAAATTGGGAGTTTCCCTAAACTATTTGCTAGGTGAAACAAAACTAGACATTCCTGAAGACTAT
TACAAGGCTAAATATAAACTCATGAAGTCTCCTGTCTATGGCGACCCGGAACGTATCAAGAAGAAGCTAAAAGATATTGA
GGAACTCTACGACAACTATATTGATATTCTACCAGAGGACGAGCTTTTTGCTATTGATATCATTGAAAGAACGTTAAATT
TTATGGTTATGGAAGAAGATAGTCTTATTGAATCTGTATTTGAAGACTATTTGACTCAAGCTTTGAAAAAAGAAGCATAT
TCCTTAAATGACCTTCTATTAATTTCATACTATGCATTACGATGTCAGGATTATGACTATGATAAAGGAATAATTGACGA
ATTTAGACGTAAATTAATTAAGCAAGAATTGCAAGGTGAAGAGCTGTTTAATATTGAATTAATGGGAGCTCTAACATCTA
TAGCTGGTATTTACGTCATGCATCATGACTATAAAGACATGAAATCTGTTGTAGATAAATTGTATGAGATTATGCATTCA
TGTATGCAACATTCCTATCAACCAGGTATCATAGTTTTTGAAGCAAAATACTATCTCTTCTATGAGAACAATAGAGAAAA
AGCAACAGAGCTCTATCATACAGCTACCCTACTAGCCGAAGCTTTTGGTGACCAAGTCTTCATCAAAAATCTTAAAATGG
AAATTGAAAAAGATTTAAACATATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (77-294)

3D structure

• AlphaFold DB: J7TIP3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	38.983	98.007	0.382
comR	Streptococcus thermophilus LMG 18311	39.31	96.346	0.379
comR	Streptococcus thermophilus LMD-9	38.966	96.346	0.375
comR	Streptococcus salivarius strain HSISS4	38.966	96.346	0.375
comR	Streptococcus salivarius SK126	39.085	94.352	0.369
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	37.457	96.678	0.362