Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ACJVC4_RS06465 Genome accession   NZ_CP177179
Coordinates   1321165..1322073 (+) Length   302 a.a.
NCBI ID   WP_002891213.1    Uniprot ID   J7TZ20
Organism   Streptococcus salivarius strain MRD-NRLLH     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1316165..1327073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVC4_RS06455 - 1319351..1320271 (-) 921 WP_002891211.1 multidrug resistance efflux transporter family protein -
  ACJVC4_RS06460 - 1320426..1320947 (-) 522 WP_224111181.1 RDD family protein -
  ACJVC4_RS06465 comR 1321165..1322073 (+) 909 WP_002891213.1 helix-turn-helix domain-containing protein Regulator
  ACJVC4_RS06470 - 1322159..1322995 (+) 837 WP_002891214.1 ABC transporter ATP-binding protein -
  ACJVC4_RS06475 - 1322988..1323707 (+) 720 WP_002891215.1 ABC transporter permease -
  ACJVC4_RS06480 comR/comR1 1323865..1324770 (+) 906 WP_002891217.1 helix-turn-helix domain-containing protein Regulator
  ACJVC4_RS06485 - 1324883..1325770 (-) 888 WP_002891218.1 hypothetical protein -
  ACJVC4_RS06490 - 1326142..1326603 (-) 462 WP_037597934.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 302 a.a.        Molecular weight: 35555.02 Da        Isoelectric Point: 4.5780

>NTDB_id=969481 ACJVC4_RS06465 WP_002891213.1 1321165..1322073(+) (comR) [Streptococcus salivarius strain MRD-NRLLH]
MSEDIKIKIGKRIREERERQGLTREHVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLGVSLNYLLGETKLDIPEEY
YQAKYKLMKSPVYGDLERIKKKLQDIEELYEKYIDILPEDELLTIDIIERTLNFMTEGEEDAIETIFEDYLTQVLKKEAY
SLNDLLLIKYYTFKCQVGDYDEEIVESFRCKLINQELQGEELFNVELIGALSAIAGIYVMHHDYKEMKSVVDKMYVLIDK
TLQQAYKPAVLVFEAKYYLYYENDINKATELYHTATVLAEAFGDQVFIKNLKMEMKKDLNTK

Nucleotide


Download         Length: 909 bp        

>NTDB_id=969481 ACJVC4_RS06465 WP_002891213.1 1321165..1322073(+) (comR) [Streptococcus salivarius strain MRD-NRLLH]
ATGTCAGAAGATATTAAAATCAAGATTGGAAAAAGAATTCGTGAAGAACGTGAACGTCAAGGGTTAACACGTGAGCACGT
TTGTGATACCGAAGAAGAATTAACAGTAAAACAACTGATGAGAATTGAACTTGGTCGTTCTTTACCAACCATTGTCAAAC
TGCAATACATCAGTGATAAATTGGGTGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGATATTCCTGAGGAGTAT
TATCAGGCTAAATATAAACTCATGAAGTCTCCTGTCTATGGCGACCTCGAGCGTATCAAGAAAAAACTACAAGATATTGA
AGAACTTTATGAAAAATATATTGATATTCTACCAGAGGACGAACTTTTAACCATTGATATCATTGAAAGAACCCTGAATT
TTATGACTGAAGGTGAAGAGGATGCTATCGAAACTATCTTTGAAGACTATCTGACTCAAGTATTGAAGAAAGAAGCATAT
TCCTTAAATGACCTCTTACTAATTAAATATTATACTTTTAAATGTCAAGTTGGTGACTATGATGAAGAAATTGTTGAAAG
TTTTCGATGTAAATTAATTAATCAAGAACTACAAGGGGAAGAGCTGTTTAACGTTGAACTGATAGGTGCTTTATCAGCTA
TAGCTGGGATATATGTGATGCATCATGACTATAAAGAAATGAAGTCTGTTGTTGATAAAATGTATGTTCTTATTGACAAG
ACACTTCAACAAGCTTATAAACCCGCAGTACTTGTTTTTGAAGCAAAATATTATTTATATTATGAAAATGACATAAATAA
AGCAACAGAGCTCTATCATACAGCCACCGTACTAGCCGAAGCCTTCGGCGACCAAGTCTTCATCAAAAATCTTAAAATGG
AAATGAAAAAAGATTTAAATACGAAATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(77-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TZ20

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMG 18311

42.414

96.026

0.407
  comR Streptococcus thermophilus LMD-9

42.414

96.026

0.407
  comR Streptococcus salivarius strain HSISS4

42.069

96.026

0.404
  comR Streptococcus salivarius SK126

42.254

94.04

0.397
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

40

97.682

0.391
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

39.175

96.358

0.377